公开(公告)号：JP3406699B2

公开(公告)日：2003-05-12

申请号：JP21694894

申请日：1994-09-12

IPC分类号： A61K8/00 ,  A61K8/40 ,  A61K8/41 ,  A61K8/42 ,  A61K8/46 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q11/00 ,  A61Q19/10 ,  C07C229/12 ,  C07C231/02 ,  C07C231/12 ,  C07C233/36 ,  C07C235/08 ,  C07C235/10 ,  C07C309/13 ,  C07C309/17 ,  C11D1/18 ,  C11D1/28 ,  C11D1/92 ,  C11D3/37 ,  A61K7/50 ,  A61K7/075

公开(公告)号：JP2001527052A

公开(公告)日：2001-12-25

申请号：JP2000526243

申请日：1998-12-22

IPC分类号： A61K9/00 ,  A61K9/127 ,  C07C217/08 ,  C07C219/06 ,  C07C235/08 ,  C07C247/04 ,  C07F9/10 ,  C08G69/10

公开(公告)号：JP3205044B2

公开(公告)日：2001-09-04

申请号：JP12407792

申请日：1992-04-17

IPC分类号： C09K11/00 ,  C07C235/00 ,  C07C235/08 ,  C07C271/12 ,  C07C271/14 ,  C07C271/16 ,  C07C275/04 ,  C07C275/06 ,  C07C275/24 ,  C07C275/28 ,  C07C323/10 ,  C07D317/54 ,  C08G69/00 ,  C08G71/00 ,  G01D15/14 ,  G03F7/004 ,  G03F7/039

公开(公告)号：JP2001510821A

公开(公告)日：2001-08-07

申请号：JP2000504094

申请日：1998-07-23

IPC分类号： C07D295/18 ,  C07B43/06 ,  C07C227/32 ,  C07C231/10 ,  C07C231/18 ,  C07C235/08 ,  C07C237/08 ,  C07C237/22 ,  C07C291/10 ,  C07D205/08 ,  C07D295/185

公开(公告)号：JP3180965B2

公开(公告)日：2001-07-03

申请号：JP33743491

申请日：1991-12-20

IPC分类号： C07C231/12 ,  C07B61/00 ,  C07C231/08 ,  C07C233/03 ,  C07C233/17 ,  C07C233/18 ,  C07C233/36 ,  C07C235/08

公开(公告)号：JP2001072741A

公开(公告)日：2001-03-21

申请号：JP2000246864

申请日：2000-08-16

申请人： SIKA AG

发明人： GERBER ULRICH ,  PAUL SCHELBERT ,  MEYER WERNER

IPC分类号： C08G63/02 ,  C07C69/708 ,  C07C69/92 ,  C07C235/08 ,  C08G18/32 ,  C08G18/42 ,  C08G18/46 ,  C08G18/66 ,  C08G63/78 ,  C08G63/91 ,  C08J11/24 ,  C08J11/26

摘要： PROBLEM TO BE SOLVED: To obtain a binder useful in the production of urethane coating materials, etc., from recycled polyesters by mixing the reaction product obtained from a polyester, a di- or poly-ol or an aminoalcohol, and a fatty acid ester with a compound selected from a diol, etc. SOLUTION: This binder comprises compounds of formulae I and/or II and at least one member selected from compounds of formulae III to VII. In the formulae, a group of formula VIII is an aromatic-group-containing polyester repeating unit; n is 1-4; A is O or N; x is 1 or 2; y is 0 or 1, provided that x+y=2 when A is N, and x is 1 and y is 0 when A is O; R1 is a polyester segment; R2 is an (OH-substituted) aliphatic, cyclic, or aromatic 1-8C hydrocarbon group, a di-, tri, or tetra-alkyl ether group, or a (poly)ester group; R3 is an OH-substituted 11-21C alkyl; R4 is H or a hydroxylalkyl; Q is an (OH- substituted) 3-6C alkyl residue; and p is 1-4. It is desirable that the binder contains 14-24 wt.%, based on the total weight of the binder, O-R1-CO groups.

公开(公告)号：JPH11500715A

公开(公告)日：1999-01-19

申请号：JP52459696

申请日：1995-11-17

IPC分类号： A61K8/00 ,  A61K8/42 ,  A61Q5/02 ,  A61Q19/10 ,  B01F17/00 ,  B01F17/22 ,  B01F17/32 ,  B01F17/42 ,  C07C233/01 ,  C07C233/04 ,  C07C233/05 ,  C07C233/17 ,  C07C233/18 ,  C07C233/57 ,  C07C235/04 ,  C07C235/08 ,  C07C237/04 ,  C07C237/08 ,  C07C309/10 ,  C07C309/17 ,  C10M133/16 ,  C10N30/00 ,  C10N40/24 ,  C11D1/10 ,  C11D1/28 ,  C11D1/29 ,  C11D1/34 ,  C11D1/52 ,  C11D1/66 ,  C11D1/88 ,  C23G5/032 ,  D06M13/402 ,  A61K7/075 ,  A61K7/50

公开(公告)号：JPH10324671A

公开(公告)日：1998-12-08

申请号：JP13354897

申请日：1997-05-23

申请人： SEIKAGAKU KOGYO CO LTD

发明人： INOKUCHI JINICHI ,  JINBO MASAYUKI ,  FUJIWARA MICHIHIRO

IPC分类号： C07D295/12 ,  A61K31/40 ,  A61K31/401 ,  A61K31/535 ,  A61K31/5375 ,  A61K31/5377 ,  A61P25/00 ,  A61P25/26 ,  A61P25/28 ,  C07C233/18 ,  C07C233/20 ,  C07C235/08 ,  C07C235/26 ,  C07C235/28 ,  C07C235/34 ,  C07D263/14 ,  C07D263/20 ,  C07D295/14

摘要： PROBLEM TO BE SOLVED: To obtain a novel aminoalcohol derivative that has excellent therapeutic effect on neurological disorder and brain-protecting action and is useful as a therapeutic agent for neurological disorder, particularly as a brain- protecting agent. SOLUTION: This novel compound is an aminoalcohol derivative represented by formula I [R is an alkyl, an alkenyl, a cycloalkyl, an aryl; R is an alkyl, a hydroxyalkyl, an alkenyl, a hydroxyalkenyl; R is a group of formula II, formula III (R and R are each H, an alkyl, piperidino); R is H, an alkyl, an amino, an alkoxy, carboxyl; n is 1-4] or its pharmaceutically acceptable salt, typically (1S, 2S)-2-decanoylamino-3-morpholino-1-phenyl-1-propyl acetate. The compound of formula I is prepared, for example, by esterification of the hydroxyl group in the compound of formula IV with a carboxylic acid or its reactive derivative corresponding to CO-(CH2 )n -R .

公开(公告)号：JPH10114732A

公开(公告)日：1998-05-06

申请号：JP28735096

申请日：1996-10-11

申请人： TAKASAGO PERFUMERY CO LTD

发明人： SAKURAI KAZUTOSHI ,  ISHIDA MASAYA ,  OGURA SANEJI

IPC分类号： C07C231/16 ,  C07C231/02 ,  C07C233/18 ,  C07C233/20 ,  C07C235/08

摘要： PROBLEM TO BE SOLVED: To provide a method for producing a primary amide derivative amt to selectively convert only the amino group of an aminodiol into the N-acylate derivative by reacting the aminodiol with a fatty acid alkyl ester in an alcohol not crystallizing at a room temperature and having a relatively high boiling point as a solvent. SOLUTION: This method for producing a primary amide derivative of formula II comprise reacting an aminodion of formula I(R is a 11-19C saturated linear aliphatic hydrocarbon with a fatty acid alkyl ester of the formula: R COOR (R is a 9-19C linear aliphatic hydrocarbon which may have a hydroxyl group at the 1-position: R is a lower alkyl) in the presence of a basic catalyst in an alcoholic solvent (preferably a 3-8C alcohol, especially n-butanol), while the lower alcohol by-produced during the reaction is distilled out from the reaction system. Thus, the objective product useful as a basic material for cosmetics having moisture-retaining effects in skins can be obtained in a high yield.

公开(公告)号：JP2743216B2

公开(公告)日：1998-04-22

申请号：JP32077890

申请日：1990-11-27

IPC分类号： A61K8/30 ,  A61K8/00 ,  A61K8/41 ,  A61K8/42 ,  A61K8/60 ,  A61K8/72 ,  A61Q19/00 ,  A61Q19/02 ,  C07C215/24 ,  C07C235/08 ,  A61K7/48 ,  A61K7/00