摘要:
PROBLEM TO BE SOLVED: To provide a film characterized in more uniformed shift from an adjoining crystallized area with less sudden changes, which can be used for LCD and OLED displays.SOLUTION: A polycrystalline film is prepared in the following steps of: (a) allowing a thin film to provide a base plate subject to laser guided melting; (b) generating a continuous laser pulse having a fluence that could sufficiently melt the film within the radiation range over entire thickness; (c) defining the maximum width (W) and minimum width (W) for irradiating a first region of the film with a first laser pulse, while a first melting bandwidth indicates a fluctuation of width along the length; (d) moving the film in the cross growth direction for longer than about a half of the Wbut shorter than the W; and (e) irradiating a second region of the film with a second laser pulse to form a second melting band width having substantially the same configuration as that of the first melting bandwidth.
摘要:
PROBLEM TO BE SOLVED: To provide a method for treating or improving an effect of a disease characterized by the accumulation of lipofuscin pigment in the retina by retarding a formation of the lipofuscin pigment in the retina.SOLUTION: The composition contains substituted C-retinoid and a pharmaceutically acceptable carrier.
摘要:
PROBLEM TO BE SOLVED: To provide a method for reversing the cancerous phenotype of a cancer cell and inducing apoptosis in a tumor cell.SOLUTION: A specific amount of nucleic acid having a melanoma differentiation associated gene (mda-7) is used for reversing the cancerous phenotype of the cancer cell or inducing the apoptosis to the tumor cell, the nucleic acid is included by a vector selected from the group consisting of adenovirus vector, adeno-associated virus vector, Epstein-Barr virus vector, vaccinia virus vector.
摘要:
PROBLEM TO BE SOLVED: To provide a method for treating the disorder of the heart of a subject. SOLUTION: The method for treating the disorder of a subject involving the loss of cardiomyocytes comprises administrating to the subject an amount of an agent effective to cause cardiomyocyte proliferation within the heart of the subject. There are provided the method for treating with an agent containing a human endothelial progenitor cells, G-CSF, GM-CSF, SDF-1, and IL-8, and furthermore the method for determining the susceptibility of a cardiomyocyte in a subject to apoptosis. COPYRIGHT: (C)2011,JPO&INPIT
摘要:
PROBLEM TO BE SOLVED: To provide an apparatus and method for obtaining high dynamic range images using a low dynamic range image sensor. SOLUTION: A captured image is normalized with respect to an exposure function after calibration to compensate for nonlinear response of an image sensor. When the exposure function is implemented using a controllable attenuation cell array, the exposure function is adjusted to minimize the number of saturated or blackened pixels within an area of pixel array exposed through a cell, to maximize the signal-to-noise ratio of the average pixel value, and to maximize the spatial smoothness of the exposure function. A dynamic range compression technique on a low dynamic range display device entails applying a smoothing filter to the exposure function used to provide the high dynamic range image and then reapplying the smoothed exposure function. Also a method is provided for providing high dynamic range images by exposing a photographic film using a spatially varying exposure function. Thus, an electronic image provided by the same process as images captured using a fixed exposure function. COPYRIGHT: (C)2010,JPO&INPIT
摘要:
PROBLEM TO BE SOLVED: To provide a method to prevent accelerated atherosclerosis in a subject predisposed thereto. SOLUTION: There is provided a method including administering polypeptide derived from a soluble receptor for advanced glycation endproducts in an amount effective to prevent accelerated atherosclerosis in a subject. Further, a method to prevent a macrovessel disease in a subject predisposed thereto which comprises administering to the subject a polypeptide derived from soluble receptor for advanced glycation endproducts in an amount effective to prevent macrovessel disease in the subject. COPYRIGHT: (C)2010,JPO&INPIT
摘要:
PROBLEM TO BE SOLVED: To provide a device for sealing and joining or incising tissue. SOLUTION: A device makes use of the controlled application of a combination of heat and pressure for sealing adjacent tissues, joining adjacent tissue, or dissecting tissue. Thereby tissue is heated for an optimal time and at optimal temperature under optimal pressure to maximize tissue seal strength while minimizing associated tissue damage. This device is lightweight and therefore portable, and is particularly useful in an outdoor condition where an external power source cannot be used. COPYRIGHT: (C)2008,JPO&INPIT
摘要:
PROBLEM TO BE SOLVED: To provide a method for generating a subtracted cDNA library of a cell. SOLUTION: The method for generating a subtracted cDNA library of a cell comprises; (a) a step to generate a cDNA library of the cell: (b) a step to isolate double-stranded DNAs from the cDNA library: (c) a step to release the double-stranded cDNA inserts from the double-stranded DNAs: (d) a step to denature the isolated double-stranded cDNA inserts: (e) a step to hybridize the denatured double-stranded cDNA inserts with a labelled single-stranded nucleic acid molecules which are to be subtracted from the cDNA library: and (f) a step to separate the hybridized labeled single-stranded nucleic acid molecule from the double-stranded cDNA inserts. The invention also provides various uses of the generated library. COPYRIGHT: (C)2008,JPO&INPIT
摘要:
PROBLEM TO BE SOLVED: To provide a system and method for reducing the surface roughness of a polycrystalline or monocrystalline thin film produced by a sequential lateral solidification process. SOLUTION: The system comprises: an excimer laser 110 for generating a plurality of excimer laser pulses of a predetermined fluence; an energy density modulator 120 for controllably modulating the fluence of the excimer laser pulses to obtain a fluence required to perfectly melt the thin film in the thickness direction or lower; a beam equalizer 144; a sample stage 170 for melting a portion corresponding to the laser pulses of the thin film; a parallel motion means for controllably moving in parallel the position of the sample stage 170 relative to the laser pulses; and a computer 100 for performing the generation of the excimer pulses and modulation of the fluence in accordance with the relative position of the sample stage 170, and thereby processing the polycrystalline or monocrystalline thin film by sequentially moving the sample stage 170 in parallel with the laser pulses. COPYRIGHT: (C)2008,JPO&INPIT
摘要:
PROBLEM TO BE SOLVED: To provide a method for inhibiting the activation of cells bearing CD40 on the surfaces of the cells by a CD40 ligand. SOLUTION: Activation of cells bearing CD40 on their cell surface by the CD40 ligand is inhibited by bringing the cells into contact with an agent inhibiting interaction between the CD40 ligand and the cells, in an amount effective to inhibit activation of the cells. Activation of cells bearing the CD40 on their surface by the CD40 ligand in a subject is inhibited by administering to the subject an agent inhibiting the interaction between the CD40 ligand and the cells, in an amount effective to inhibit the activation of the cells. Conditions dependent on CD40 ligand-induced activation of CD40-bearing cells are treated. COPYRIGHT: (C)2007,JPO&INPIT