公开(公告)号：US09408556B2

公开(公告)日：2016-08-09

申请号：US13990007

申请日：2010-12-01

Applicant: Ping Wang ,  Di Wang ,  Le Wang ,  Jin Yu ,  Kai Yu ,  Yishan Wang ,  Lin Wang ,  Cong Zhao

Inventor： Ping Wang ,  Di Wang ,  Le Wang ,  Jin Yu ,  Kai Yu ,  Yishan Wang ,  Lin Wang ,  Cong Zhao

IPC: A61B5/08 ,  G01N33/00 ,  G01N33/497 ,  A61B5/097

CPC classification number: A61B5/082 ,  A61B5/097 ,  G01N33/0047 ,  G01N33/497

Abstract: The present embodiments disclose a device including a module for sampling, separating and enriching a detected object, an exhaled breath condensates (EBCs) detection module and a combined volatile organic compounds (VOCs) detection module. The sampling module is connected with the EBCs detection module via a syringe pump for sample injection and is connected with the combined VOCs detection module by a capillary separation column. EBCs and VOCs in human exhaled breath are simultaneously sampled, separated and condensed; the heavy metal ions, cell factors, etc. in the collected EBCs are detected with a light addressable potentiometric sensor (LAPS); the condensed VOCs can be quantitatively detected by the combined VOCs detection module with a high sensitivity; and a heating rod and a platinum resistor can be conveniently replaced because a separated outlet heating piece is designed in the combined VOCs detection module.

Abstract translation: 本实施例公开了一种包括用于对检测到的物体进行取样，分离和富集的模块，呼出呼吸冷凝物（EBC）检测模块和组合的挥发性有机化合物（VOC））检测模块的装置。 采样模块通过注射泵与EBC检测模块连接，用于注射样品，并通过毛细管分离柱与组合的VOC检测模块连接。 人呼吸中的EBC和VOCs被同时取样，分离和浓缩; 用光寻址电位传感器（LAPS）检测收集的EBC中的重金属离子，细胞因子等; 可以通过组合的VOC检测模块以高灵敏度定量检测浓缩的VOC; 并且可以方便地更换加热棒和铂电阻器，因为在组合的VOC检测模块中设计了分离的出口加热片。

公开(公告)号：US20130214783A1

公开(公告)日：2013-08-22

申请号：US13770144

申请日：2013-02-19

Applicant: Cong Zhao

Inventor： Cong Zhao

IPC: G01R33/54

CPC classification number: G01R33/54 ,  G01R33/4828 ,  G01R33/5617 ,  G01R33/56518

Abstract: In an imaging method and device for water/fat separation in MRI using a two-point Dixon FSE sequence, each refocusing RF pulse corresponds to two readout gradients of the same polarity, each being center-divided into a smaller rear part and a larger front part, and one rephasing gradient of opposite polarity. In running the FSE sequence, each echo signal acquired is subjected to an FFT, to reconstruct an image with water and fat in phase and an image with water and fat in opposed phases. Data of each echo signal are subjected to a partial Fourier transform; and the in-phase water/fat image and the opposite-phase water/fat image are subjected to a water/fat separation algorithm, to obtain a pure water image and a pure fat image.

Abstract translation: 在使用两点Dixon FSE序列的MRI中的水/脂肪分离的成像方法和装置中，每个重聚焦RF脉冲对应于相同极性的两个读出梯度，每个读出梯度被中心分成较小的后部和较大的前部 部分和一个相反极性的反相梯度。 在运行FSE序列时，获取的每个回波信号经受FFT，以相位相位的水和脂肪重建图像，并且在相对相位中重新构建具有水和脂肪的图像。 每个回波信号的数据进行部分傅里叶变换; 同相水/脂肪图像和反相水/脂肪图像进行水/脂肪分离算法，以获得纯净水图像和纯净脂肪图像。

公开(公告)号：US09507001B2

公开(公告)日：2016-11-29

申请号：US13923757

申请日：2013-06-21

Applicant: Qiong Zhang ,  Cong Zhao

Inventor： Qiong Zhang ,  Cong Zhao

IPC: G01R33/54 ,  G01R33/567 ,  G01R33/56 ,  G01R33/563

CPC classification number: G01R33/543 ,  G01R33/5607 ,  G01R33/5635 ,  G01R33/5676

Abstract: In a magnetic resonance imaging method and apparatus, navigation data are collected in a navigation acquisition timeslot of a scanning sequence. A determination as to whether to accept or reject echo data that are subsequently collected in multiple echo acquisition timeslots is made. If the phase relationship of the navigation data and the reference data in k-space is greater than or equal to the reference value, the collected echo data are accepted and if the aforementioned phase in k-space is less than the reference value, the collected echo data will be rejected, and sequential scanning will be performed again, and the navigation data again will be collected using the navigation acquisition timeslot, and the aforementioned determination is repeated.

Abstract translation: 在磁共振成像方法和装置中，导航数据被收集在扫描序列的导航获取时隙中。 做出是否接受或拒绝随后在多个回波采集时隙中收集的回波数据的确定。 如果导航数据和k空间中的参考数据的相位关系大于或等于参考值，则接收收集的回波数据，如果k空间中的上述相位小于参考值，则收集 回波数据将被拒绝，并且将再次执行顺序扫描，并且将使用导航获取时隙再次收集导航数据，并且重复上述确定。

公开(公告)号：US20140285193A1

公开(公告)日：2014-09-25

申请号：US14221614

申请日：2014-03-21

Applicant: Yu Qing Huang ,  Cong Zhao

Inventor： Yu Qing Huang ,  Cong Zhao

IPC: G01R33/36

CPC classification number: G01R33/4833 ,  G01R33/5616 ,  G01R33/56341

Abstract: In an RF excitation method and device for a magnetic resonance imaging system, the RF pulses are emitted in a STEAM sequence, the STEAM sequence including, in time order, a first 90-degree excitation pulse, a second 90-degree excitation pulse and a third 90-degree excitation pulse. Gradient pulses are activated that act in cooperation with the STEAM sequence, the gradient pulses including, in time order, a first gradient pulse, a second gradient pulse and a third gradient pulse. Each of the gradient pulses is activated simultaneously with the corresponding RF pulse. The direction of each of the gradient pulses is the vector sum of multiple gradient pulses in different directions, the directions of any two of the gradient pulses being the same and intersecting with the direction of another of the gradient pulses.

Abstract translation: 在用于磁共振成像系统的RF激励方法和装置中，RF脉冲以STEAM序列发射，STEAM序列按时间顺序包括第一90度激发脉冲，第二90度激发脉冲和 第三个90度激发脉冲。 梯度脉冲被激活，其与STEAM序列协作起作用，梯度脉冲按时间顺序包括第一梯度脉冲，第二梯度脉冲和第三梯度脉冲。 每个梯度脉冲与相应的RF脉冲同时激活。 每个梯度脉冲的方向是不同方向上的多个梯度脉冲的矢量和，任何两个梯度脉冲的方向相同并且与另一梯度脉冲的方向相交。

公开(公告)号：US09897676B2

公开(公告)日：2018-02-20

申请号：US14221614

申请日：2014-03-21

Applicant: Yu Qing Huang ,  Cong Zhao

Inventor： Yu Qing Huang ,  Cong Zhao

IPC: G01R33/483 ,  G01R33/563 ,  G01R33/561

CPC classification number: G01R33/4833 ,  G01R33/5616 ,  G01R33/56341

Abstract: In an RF excitation method and device for a magnetic resonance imaging system, the RF pulses are emitted in a STEAM sequence, the STEAM sequence including, in time order, a first 90-degree excitation pulse, a second 90-degree excitation pulse and a third 90-degree excitation pulse. Gradient pulses are activated that act in cooperation with the STEAM sequence, the gradient pulses including, in time order, a first gradient pulse, a second gradient pulse and a third gradient pulse. Each of the gradient pulses is activated simultaneously with the corresponding RF pulse. The direction of each of the gradient pulses is the vector sum of multiple gradient pulses in different directions, the directions of any two of the gradient pulses being the same and intersecting with the direction of another of the gradient pulses.

公开(公告)号：US20130342204A1

公开(公告)日：2013-12-26

申请号：US13923757

申请日：2013-06-21

Applicant: Qiong Zhang ,  Cong Zhao

Inventor： Qiong Zhang ,  Cong Zhao

IPC: G01R33/54

CPC classification number: G01R33/543 ,  G01R33/5607 ,  G01R33/5635 ,  G01R33/5676

Abstract: In a magnetic resonance imaging method and apparatus, navigation data are collected in a navigation acquisition timeslot of a scanning sequence. A determination as to whether to accept or reject echo data that are subsequently collected in multiple echo acquisition timeslots is made. If the phase relationship of the navigation data and the reference data in k-space is greater than or equal to the reference value, the collected echo data are accepted and if the aforementioned phase in k-space is less than the reference value, the collected echo data will be rejected, and sequential scanning will be performed again, and the navigation data again will be collected using the navigation acquisition timeslot, and the aforementioned determination is repeated.

Abstract translation: 在磁共振成像方法和装置中，导航数据被收集在扫描序列的导航获取时隙中。 做出是否接受或拒绝随后在多个回波采集时隙中收集的回波数据的确定。 如果导航数据和k空间中的参考数据的相位关系大于或等于参考值，则接收收集的回波数据，如果k空间中的上述相位小于参考值，则收集 回波数据将被拒绝，并且将再次执行顺序扫描，并且将使用导航获取时隙再次收集导航数据，并且重复上述确定。

公开(公告)号：US09285447B2

公开(公告)日：2016-03-15

申请号：US13770144

申请日：2013-02-19

Applicant: Cong Zhao

Inventor： Cong Zhao

IPC: G01R33/54 ,  G01R33/48 ,  G01R33/561 ,  G01R33/565

CPC classification number: G01R33/54 ,  G01R33/4828 ,  G01R33/5617 ,  G01R33/56518

Abstract: In an imaging method and device for water/fat separation in MRI using a two-point Dixon FSE sequence, each refocusing RF pulse corresponds to two readout gradients of the same polarity, each being center-divided into a smaller rear part and a larger front part, and one rephasing gradient of opposite polarity. In running the FSE sequence, each echo signal acquired is subjected to an FFT, to reconstruct an image with water and fat in phase and an image with water and fat in opposed phases. Data of each echo signal are subjected to a partial Fourier transform; and the in-phase water/fat image and the opposite-phase water/fat image are subjected to a water/fat separation algorithm, to obtain a pure water image and a pure fat image.

Abstract translation: 在使用两点Dixon FSE序列的MRI中的水/脂肪分离的成像方法和装置中，每个重聚焦RF脉冲对应于相同极性的两个读出梯度，每个读出梯度被中心分成较小的后部和较大的前部 部分和一个相反极性的反相梯度。 在运行FSE序列时，获取的每个回波信号经受FFT，以相位相位的水和脂肪重建图像，并且在相对相位中重新构建具有水和脂肪的图像。 每个回波信号的数据进行部分傅里叶变换; 同相水/脂肪图像和反相水/脂肪图像进行水/脂分离算法，以获得纯净水图像和纯净脂肪图像。

公开(公告)号：US20130253360A1

公开(公告)日：2013-09-26

申请号：US13990007

申请日：2010-12-01

Applicant: Ping Wang ,  Di Wang ,  Le Wang ,  Jin Yu ,  Kai Yu ,  Yishan Wang ,  Lin Wang ,  Cong Zhao

Inventor： Ping Wang ,  Di Wang ,  Le Wang ,  Jin Yu ,  Kai Yu ,  Yishan Wang ,  Lin Wang ,  Cong Zhao

IPC: A61B5/08 ,  A61B5/097

CPC classification number: A61B5/082 ,  A61B5/097 ,  G01N33/0047 ,  G01N33/497

Abstract: The present invention discloses an integrated analysis device for simultaneously detecting exhaled breath condensates (EBCs) and volatile organic compounds (VOCs) in human exhaled breath. The device comprises a module for sampling, separating and enriching a detected object, an EBCs detection module and a combined VOCs detection module. The module for sampling, separating and enriching a detected object is connected with the EBCs detection module via a syringe pump for sample injection. The module for sampling, separating and enriching a detected object is connected with the combined VOCs detection module by a capillary separation column. In the present invention, it is achieved that EBCs and VOCs in human exhaled breath are simultaneously sampled, separated and condensed; the heavy metal ions, cell factors, etc. in the collected EBCs are detected with a light addressable potentiometric sensor (LAPS); the condensed VOCs can be quantitatively detected by the combined VOCs detection module with a high sensitivity; and a heating rod and a platinum resistor can be conveniently replaced because a separated outlet heating piece is designed in the combined VOCs detection module.

Abstract translation: 本发明公开了一种综合分析装置，用于同时检测人呼出的呼出气体浓缩物（EBC）和挥发性有机化合物（VOC）。 该装置包括用于对被检测物体进行采样，分离和富集的模块，EBC检测模块和组合的VOC检测模块。 用于取样，分离和浓缩检测到的物体的模块通过注射泵与EBC检测模块连接，用于进样。 用于采样，分离和浓缩检测到的物体的模块通过毛细管分离柱与组合的VOC检测模块连接。 在本发明中，实现了呼气呼吸中的EBCs和VOCs被同时取样，分离和浓缩; 用光寻址电位传感器（LAPS）检测收集的EBC中的重金属离子，细胞因子等; 可以通过组合的VOC检测模块以高灵敏度定量检测浓缩的VOC; 并且可以方便地更换加热棒和铂电阻器，因为在组合的VOC检测模块中设计了分离的出口加热片。