公开(公告)号：US20220396631A1

公开(公告)日：2022-12-15

申请号：US17595637

申请日：2020-05-19

Applicant: Lu HUANG ,  Brian GRANDA ,  John BLANKENSHIP ,  Aida ABUJOUB ,  Tony FLEMING ,  Haihui LU ,  Connie HONG ,  Brian HOLMBERG ,  Novartis AG

Inventor： Brian Walter Granda ,  John Blankenship ,  Aida Abujoub ,  Tony Fleming ,  Lu Huang ,  Connie Hong ,  Brian Holmberg ,  Haihui Lu

IPC: C07K16/28

Abstract: The present disclosure provides multispecific binding molecules that specifically bind to BCMA, a component of a human T-cell receptor complex and either CD2 or a tumor associated antigen, conjugates comprising the multispecific binding molecules, and pharmaceutical compositions comprising the multispecific binding molecules and the conjugates The disclosure further provides methods of using the multispecific binding molecules to treat disease and disorders associated with expression of BCMA. The disclosure yet further provides recombinant host cells engineered to express the multispecific binding molecules and methods of producing the multispecific binding molecules by culturing the host cells under conditions in which the multispecific binding molecules are expressed.

公开(公告)号：US09331487B2

公开(公告)日：2016-05-03

申请号：US13827630

申请日：2013-03-14

Applicant: Zhenhuan Yuan ,  Shaofeng Zhang ,  Haihui Lu ,  Lixiang Wei ,  Russel J. Kerkman ,  Richard Lukaszewski ,  Ahmed Mohamed Sayed Ahmed ,  Robert J. Breitzmann

Inventor： Zhenhuan Yuan ,  Shaofeng Zhang ,  Haihui Lu ,  Lixiang Wei ,  Russel J. Kerkman ,  Richard Lukaszewski ,  Ahmed Mohamed Sayed Ahmed ,  Robert J. Breitzmann

IPC: H02J3/38

CPC classification number: H02J3/382 ,  H02J3/386 ,  H02J2003/388 ,  Y02E10/763 ,  Y10T307/642

Abstract: Methods and apparatus are presented for unintentional islanding detection for grid tie converters in which the phase angle disturbance is introduced by modification of grid side converter switching control signals and a mismatch of reactive power between generation and the grid load is formed upon the occurrence of unintentional islanding, where the applied phase disturbance is determined according to two pre-defined curves to form an equivalent positive feedback at different frequencies to prevent the converter from forming an island at a new stable frequency after the grid is disconnected.

Abstract translation: 给出了并网转换器的无意孤立检测方法和装置，其中通过修改电网侧转换器开关控制信号引入相位角扰动，并且在无意孤岛发生时形成发电与电网负载之间的无功功率失配 其中施加的相位干扰根据两个预定义曲线确定，以在不同频率处形成等效的正反馈，以防止转换器在网格断开之后以新的稳定频率形成岛。

公开(公告)号：US08742767B2

公开(公告)日：2014-06-03

申请号：US12611719

申请日：2009-11-03

Applicant: David M. Messersmith ,  Douglas J. Bader ,  Haihui Lu ,  Thomas A. Nondahl ,  Zhenhuan Yuan

Inventor： David M. Messersmith ,  Douglas J. Bader ,  Haihui Lu ,  Thomas A. Nondahl ,  Zhenhuan Yuan

IPC: G01R31/06

CPC classification number: G01R31/343 ,  G01R27/08 ,  G01R27/2611 ,  H02P23/14

Abstract: A method of estimating stator resistance of an induction motor includes applying voltage pulses through two phase paths of the motor for a plurality of electrical cycles to inject current in the motor, wherein the voltage pulses are applied until rotor flux of the motor is substantially stabilized and measuring stator voltage and stator current in response to the applied voltage pulses for each of the plurality of electrical cycles. The method also includes calculating the stator resistance based upon the measured stator voltages and the stator currents.

Abstract translation: 一种估计感应电动机的定子电阻的方法包括：通过电动机的两个相位路径将电压脉冲施加多个电循环以在电动机中注入电流，其中施加电压脉冲，直到电机的转子磁通量基本稳定， 响应于所述多个电循环中的每一个的所施加的电压脉冲来测量定子电压和定子电流。 该方法还包括基于所测量的定子电压和定子电流来计算定子电阻。

公开(公告)号：US08547050B2

公开(公告)日：2013-10-01

申请号：US13473985

申请日：2012-05-17

Applicant: Haihui Lu ,  David M. Messersmith ,  Thomas A. Nondahl

Inventor： Haihui Lu ,  David M. Messersmith ,  Thomas A. Nondahl

IPC: G01P3/00 ,  H02P1/28

CPC classification number: H02P23/0004

Abstract: Systems, methods, and devices are disclosed, including an induction-motor controller having a phase path; a solid-state switch interposed on the phase path; and a controller coupled to the solid-state switch. In certain embodiments, the controller is configured to switch the solid-state switch so that the solid-state switch is conductive during a conduction angle of a cycle of an incoming AC power waveform conveyed by the phase path, calculate the conduction angle based on a generally sinusoidal reference value that has a frequency lower than a frequency of the incoming AC power waveform, and adjust the generally sinusoidal reference value based on a value indicative of flux in a load coupled to the phase path.

公开(公告)号：US07298105B1

公开(公告)日：2007-11-20

申请号：US11614239

申请日：2006-12-21

Applicant: Haihui Lu ,  Wei Qian

Inventor： Haihui Lu ,  Wei Qian

IPC: H02P21/06

CPC classification number: H02P21/0021 ,  H02P21/0017 ,  H02P21/141 ,  H02P21/18 ,  H02P21/20 ,  H02P21/26 ,  H02P21/32 ,  H02P21/34 ,  H02P31/00 ,  H02P2203/05 ,  H02P2203/09 ,  H02P2207/01 ,  Y10S388/906 ,  Y10S388/917

Abstract: Motor drives, motor speed controllers, motor speed estimation systems, and methods are presented for controlling motor speed and for estimating motor speed, in which a speed estimate controller provides a rotor speed estimate based on a first error term from a torque-based MRAS component for a first range of motor speeds and based on a second error term from a rotor flux-based MRAS component for a second range of speeds.

Abstract translation: 提出了电机驱动器，电动机速度控制器，电动机速度估计系统和方法，用于控制电动机速度和估计电动机速度，其中速度估计控制器基于来自基于扭矩的MRAS分量的第一误差项提供转子速度估计 对于第一范围的电动机速度，并且基于来自用于第二速度范围的基于转子磁通的MRAS分量的第二误差项。

公开(公告)号：US20070216337A1

公开(公告)日：2007-09-20

申请号：US11614239

申请日：2006-12-21

Applicant: Haihui Lu ,  Wei Qian

Inventor： Haihui Lu ,  Wei Qian

IPC: H02P27/04

CPC classification number: H02P21/0021 ,  H02P21/0017 ,  H02P21/141 ,  H02P21/18 ,  H02P21/20 ,  H02P21/26 ,  H02P21/32 ,  H02P21/34 ,  H02P31/00 ,  H02P2203/05 ,  H02P2203/09 ,  H02P2207/01 ,  Y10S388/906 ,  Y10S388/917

Abstract: Motor drives, motor speed controllers, motor speed estimation systems, and methods are presented for controlling motor speed and for estimating motor speed, in which a speed estimate controller provides a rotor speed estimate based on a first error term from a torque-based MRAS component for a first range of motor speeds and based on a second error term from a rotor flux-based MRAS component for a second range of speeds.

Abstract translation: 提出了电机驱动器，电动机速度控制器，电动机速度估计系统和方法，用于控制电动机速度和估计电动机速度，其中速度估计控制器基于来自基于扭矩的MRAS分量的第一误差项提供转子速度估计 对于第一范围的电动机速度，并且基于来自用于第二速度范围的基于转子磁通的MRAS分量的第二误差项。

公开(公告)号：US20140268928A1

公开(公告)日：2014-09-18

申请号：US13845416

申请日：2013-03-18

Applicant: Lixiang Wei ,  Yuan Xiao ,  Haihui Lu ,  Douglas B. Weber

Inventor： Lixiang Wei ,  Yuan Xiao ,  Haihui Lu ,  Douglas B. Weber

IPC: H02M5/458

CPC classification number: H02M5/458 ,  H02M7/49 ,  H02M2001/325

Abstract: Multilevel inverters, power cells and bypass methods are presented in which a power cell switching circuit is selectively disconnected from the power cell output, and a bypass which is closed to connect first and second cell output terminals to selectively bypass a power stage of a multilevel inverter, with an optional AC input switch to selectively disconnect the AC input from the power cell switching circuit during bypass.

Abstract translation: 提出了多电平逆变器，功率单元和旁路方法，其中功率单元开关电路与功率单元输出选择性地断开，并且闭合的旁路连接第一和第二单元输出端子以选择性地旁路多电平逆变器的功率级 具有可选的AC输入开关，用于在旁路期间选择性地断开AC电源与电源开关电路的输入。

公开(公告)号：US08736091B2

公开(公告)日：2014-05-27

申请号：US12818895

申请日：2010-06-18

Applicant: Lixiang Wei ,  Russel J. Kerkman ,  Richard A. Lukaszewski ,  Haihui Lu ,  Zhenhuan Yuan

Inventor： Lixiang Wei ,  Russel J. Kerkman ,  Richard A. Lukaszewski ,  Haihui Lu ,  Zhenhuan Yuan

IPC: H02P9/04 ,  G01B3/52

CPC classification number: H02M7/537 ,  G01B3/52 ,  G05F1/67 ,  H02M1/32 ,  H02P9/007

Abstract: The present techniques include methods and systems for operating converter to maintain a lifespan of the converter. In some embodiments, the operating frequency of the converter may be increased such that stress may be reduced on the bond wires of the converter. More specifically, embodiments involve calculating the aging parameters for certain operating conditions of the converter operating in a maximum power point tracking (MPPT) mode and determining whether the MPPT operation results in aging the converter to a point which reduces the converter lifespan below a desired lifespan. If the MPPT operation reduces the converter lifespan below the desired lifespan, the frequency of the converter may be increased such that the converter may be controlled to operate at a percentage of MPPT. Thus, in some embodiments, power output may be optimized with respect to maintaining a desired lifespan of the converter.

Abstract translation: 本技术包括用于操作转换器以保持转换器寿命的方法和系统。 在一些实施例中，可以增加转换器的工作频率，使得可以在转换器的接合线上减小应力。 更具体地，实施例涉及为以最大功率点跟踪（MPPT）模式操作的转换器的某些操作条件计算老化参数，并且确定MPPT操作是否导致转换器老化到将转换器寿命降低到期望寿命以下的点 。 如果MPPT操作将转换器寿命降低到期望的寿命以下，则可以增加转换器的频率，使得可以将转换器控制为以MPPT的百分比进行操作。 因此，在一些实施例中，可以相对于维持转换器的期望寿命来优化功率输出。

公开(公告)号：US08432052B2

公开(公告)日：2013-04-30

申请号：US12789285

申请日：2010-05-27

Applicant: Haihui Lu ,  Lixiang Wei ,  Richard A. Lukaszewski ,  Russel J. Kerkman ,  Zhenhuan Yuan

Inventor： Haihui Lu ,  Lixiang Wei ,  Richard A. Lukaszewski ,  Russel J. Kerkman ,  Zhenhuan Yuan

IPC: H02P9/04 ,  G05D3/12

CPC classification number: H02P9/105 ,  H02J3/386 ,  H02J3/50 ,  H02M5/4585 ,  H02P9/007 ,  H02P2101/15

Abstract: The present techniques include methods and systems for operating a wind power system to maintain a lifespan of the rotor side converter. In some embodiments, the current of the rotor side converter may be minimized to reduce the stress and/or junction temperature variation in the switching transistors and bond wires of the converter. More specifically, embodiments involve using a minimal current in the rotor side converter based on the rotor side and grid side reactive powers. If the grid side reactive power is greater than a maximum grid side reactive power, the grid side reactive power may be reduced. Further, if the total reactive power does not meet the grid reactive power requirements, the minimal current in the rotor side converter may be adjusted such that the system may sufficiently power the grid.

Abstract translation: 本技术包括用于操作风力发电系统以维持转子侧转换器的寿命的方法和系统。 在一些实施例中，转子侧转换器的电流可以最小化，以减小转换器的开关晶体管和接合线中的应力和/或结温变化。 更具体地，实施例涉及在转子侧转换器中基于转子侧和电网侧无功功率使用最小电流。 如果电网侧无功功率大于最大电网侧的无功功率，则电网侧的无功功率可能会降低。 此外，如果总无功功率不满足电网无功功率要求，则可以调节转子侧转换器中的最小电流，使得系统可以对电网充分供电。

公开(公告)号：US07701165B2

公开(公告)日：2010-04-20

申请号：US11932624

申请日：2007-10-31

Applicant: Wei Quian ,  Haihui Lu ,  Thomas A. Nondahl

Inventor： Wei Quian ,  Haihui Lu ,  Thomas A. Nondahl

IPC: H02P27/16

CPC classification number: H02P23/14 ,  H02P27/16 ,  Y10S388/917

Abstract: An induction motor controller that may include three phase paths leading from a power input to a power output, a solid-state switching device interposed between the power input and the power output on each of the three phase paths, a voltage sensor coupled to two of the phase paths between the solid-state switching device and the power output, a current sensor on one of the phase paths, a processor communicatively coupled to the voltage sensor, the current sensor, and the solid state switching device; and a memory coupled to the processor. The processor may be configured to calculate a motor parameter based on a signal from the voltage sensor and a signal from the current sensor and store the calculated motor parameter in memory.

Abstract translation: 一种感应电动机控制器，其可以包括从电力输入到功率输出的三相路径，插在电源输入端和三相路径中的每一个上的功率输出端之间的固态开关装置， 固态开关器件和功率输出之间的相位路径，一个相位路径上的电流传感器，通信地耦合到电压传感器，电流传感器和固态开关器件的处理器; 以及耦合到处理器的存储器。 处理器可以被配置为基于来自电压传感器的信号和来自电流传感器的信号来计算电动机参数，并将计算的电动机参数存储在存储器中。