公开(公告)号：US09907766B2

公开(公告)日：2018-03-06

申请号：US15389639

申请日：2016-12-23

Applicant: AJINOMOTO CO., INC.

Inventor： Yoshiro Kitahara ,  Koji Ohsumi ,  Seiji Kitajima ,  Shimpei Ogawa

IPC: A61K31/17 ,  C07C335/20 ,  C07C335/16

CPC classification number: A61K31/17 ,  A61K31/277 ,  C07C335/16 ,  C07C335/20

Abstract: Sweetness receptor antagonists represented by formula (I): wherein each symbol is described herein, are useful for the prophylaxis or treatment of metabolic syndrome, diabetes, obesity and the like.

公开(公告)号：US20150276710A1

公开(公告)日：2015-10-01

申请号：US14666606

申请日：2015-03-24

Applicant: AJINOMOTO CO., INC.

Inventor： Seiji Kitajima ,  Yutaka Ishiwatari

IPC: G01N33/50 ,  C07K14/72

CPC classification number: G01N33/502 ,  C07K14/705 ,  C07K14/723 ,  C07K2319/00 ,  G01N2333/705 ,  G01N2500/02

Abstract: A sweet taste substance or a sweet taste-regulating substance is detected by contacting a test substance with a cell that expresses a chimeric protein of human T1R2 and mouse T1R2, and/or a chimeric protein of human T1R3 and mouse T1R3, and may further express a G protein α subunit, and by detecting an interaction between the chimeric proteins and the test substance.

Abstract translation: 通过使测试物质与表达人T1R2和小鼠T1R2的嵌合蛋白的细胞和/或人T1R3和小鼠T1R3的嵌合蛋白接触来检测甜味物质或甜味调节物质，并且可进一步表达 G蛋白α亚单位，并通过检测嵌合蛋白质和测试物质之间的相互作用。

公开(公告)号：US20140030380A1

公开(公告)日：2014-01-30

申请号：US14043195

申请日：2013-10-01

Applicant: AJINOMOTO CO., INC.

Inventor： Seiji Kitajima ,  Yuzuru Eto ,  Takaho Tajima

IPC: A23L1/22

CPC classification number: A23L27/21 ,  A23J3/16 ,  A23J3/346 ,  A23L27/26 ,  A23L27/88 ,  A23V2002/00 ,  C12P21/06 ,  A23V2200/16 ,  A23V2250/5488 ,  A23V2250/55

Abstract: The present invention provides a production method of a food, which can effectively enhance a taste without conferring an unpreferable or undesirable flavor, and a method for enhancing a taste of food. The present invention provides a method of producing a food with an enhanced taste, including by adding a peptide mixture obtained by hydrolyzing, with an enzyme, a composition containing β-conglycinin, and a method of enhancing the taste of food, including a step of adding the peptide mixture.

Abstract translation: 本发明提供一种食品的制造方法，其能够有效地增加味道而不赋予不优选或不期望的风味，以及增加食品味道的方法。 本发明提供一种生产具有增强味道的食品的方法，包括通过加入通过用酶水解含有β-伴大豆球蛋白的组合物获得的肽混合物和增强食物味道的方法，包括步骤 加入肽混合物。

公开(公告)号：US09341616B2

公开(公告)日：2016-05-17

申请号：US14666606

申请日：2015-03-24

Applicant: AJINOMOTO CO., INC.

Inventor： Seiji Kitajima ,  Yutaka Ishiwatari

IPC: C07K14/705 ,  C07K19/00 ,  G01N33/557 ,  G01N33/50 ,  C07K14/72

CPC classification number: G01N33/502 ,  C07K14/705 ,  C07K14/723 ,  C07K2319/00 ,  G01N2333/705 ,  G01N2500/02

Abstract: A sweet taste substance or a sweet taste-regulating substance is detected by contacting a test substance with a cell that expresses a chimeric protein of human T1R2 and mouse T1R2, and/or a chimeric protein of human T1R3 and mouse T1R3, and may further express a G protein α subunit, and by detecting an interaction between the chimeric proteins and the test substance.

Abstract translation: 通过使测试物质与表达人T1R2和小鼠T1R2的嵌合蛋白的细胞和/或人T1R3和小鼠T1R3的嵌合蛋白接触来检测甜味物质或甜味调节物质，并且可进一步表达 G蛋白α亚单位，并通过检测嵌合蛋白质和测试物质之间的相互作用。