公开(公告)号：US11890450B2

公开(公告)日：2024-02-06

申请号：US16297408

申请日：2019-03-08

Applicant: AMGEN INC.

Inventor： Lawrence Scott Ring ,  Tohid Pirbodaghi ,  Samin Akbari ,  Daniel Eduardo Groszmann ,  Mehran Mojarrad ,  Mark Gordon ,  Mikhail Tikh ,  Jimmie L. Ward ,  Scott R. Gibson ,  Sheldon B. Moberg ,  Joshua Tamsky ,  Paul Faucher ,  Jeff Lind

IPC: A61M5/168 ,  A61M5/14 ,  A61M5/142 ,  A61M5/158 ,  A61M39/24 ,  A61M5/145 ,  A61M5/155

CPC classification number: A61M5/16813 ,  A61M5/1413 ,  A61M5/14248 ,  A61M5/158 ,  A61M5/16822 ,  A61M39/24 ,  A61M5/14526 ,  A61M5/155 ,  A61M2005/1403 ,  A61M2005/1406 ,  A61M2005/14252 ,  A61M2039/244 ,  A61M2039/2406 ,  A61M2039/248 ,  A61M2039/2426 ,  A61M2205/3561 ,  A61M2205/505 ,  A61M2205/7527 ,  A61M2205/7536 ,  A61M2209/045

Abstract: A drug delivery device includes a housing defining a shell and an inner volume, a container, a drive mechanism, a needle assembly, a fluid flow connection, and a backflow prevention mechanism. The container has an inner volume to contain a medicament to be administered to a user. The drive mechanism is at least partially disposed within the housing and exerts a force to urge the medicament out the container. The fluid flow connection is coupled to the container and the needle assembly and allows the medicament to flow from the container to the needle assembly to be administered. The backflow prevention mechanism is associated with at least one of the container, the fluid flow connection, or the needle assembly and includes at least one flow restrictor to restrict a fluid from flowing from the needle assembly to the container.

公开(公告)号：US20240100247A1

公开(公告)日：2024-03-28

申请号：US17767466

申请日：2020-10-01

Applicant: AMGEN INC.

Inventor： Tohid Pirbodaghi ,  Joshua Tamsky ,  Paul Daniel Faucher ,  Jeff Lind ,  Scott R. Gibson ,  Sheldon B. Moberg ,  Samin Akbari

IPC: A61M5/142 ,  A61M5/145 ,  A61M5/168 ,  A61M39/26

CPC classification number: A61M5/14248 ,  A61M5/1454 ,  A61M5/16881 ,  A61M39/26 ,  A61M2005/14252

Abstract: A drug delivery device includes a housing, a container disposed in the housing, an activation mechanism, a needle insertion mechanism, and a fluid flow path. The container has an inner volume to contain a medicament which is urged out of the container by the activation mechanism. The needle insertion mechanism includes an actuation assembly adapted to insert a needle and a cannula to deliver the medicament from the container and a valve assembly. The fluid flow connection is coupled with the container and the needle insertion mechanism and is adapted to allow the medicament to flow from the container to the needle insertion mechanism. The valve assembly is repeatedly movable between at least a valve open position and a valve closed position to selectively allow and restrict the medicament to flow through the needle and/or the cannula.

公开(公告)号：US20220362462A1

公开(公告)日：2022-11-17

申请号：US17637507

申请日：2020-09-09

Applicant: AMGEN INC.

Inventor： Tohid Pirbodaghi ,  Paul Daniel Faucher ,  Joshua Tamsky ,  Scott Robert Gibson ,  Sheldon B. Moberg ,  Jeff Lind

IPC: A61M5/168 ,  A61M5/158 ,  A61M5/32

Abstract: A drug delivery device includes a housing, a container disposed in the housing, an activation mechanism, a needle insertion mechanism, a fluid flow connection, and a valve in fluid communication with the fluid flow connection and the needle insertion mechanism. The container has an inner volume to contain a medicament which is urged out of the container by the activation mechanism. The needle insertion mechanism is adapted to insert a needle and/or a cannula to deliver the medicament from the container via the fluid flow connection. The valve is in fluid communication with the fluid flow connection and needle insertion mechanism, and is movable between first and second positions. Upon insertion of the needle and/or the cannula, the valve remains in the first position whereby fluid flow is restricted. At a later time, the valve is urged to the second position whereby fluid may flow through the needle or cannula.