公开(公告)号：US11890450B2

公开(公告)日：2024-02-06

申请号：US16297408

申请日：2019-03-08

Applicant: AMGEN INC.

Inventor： Lawrence Scott Ring ,  Tohid Pirbodaghi ,  Samin Akbari ,  Daniel Eduardo Groszmann ,  Mehran Mojarrad ,  Mark Gordon ,  Mikhail Tikh ,  Jimmie L. Ward ,  Scott R. Gibson ,  Sheldon B. Moberg ,  Joshua Tamsky ,  Paul Faucher ,  Jeff Lind

IPC: A61M5/168 ,  A61M5/14 ,  A61M5/142 ,  A61M5/158 ,  A61M39/24 ,  A61M5/145 ,  A61M5/155

CPC classification number: A61M5/16813 ,  A61M5/1413 ,  A61M5/14248 ,  A61M5/158 ,  A61M5/16822 ,  A61M39/24 ,  A61M5/14526 ,  A61M5/155 ,  A61M2005/1403 ,  A61M2005/1406 ,  A61M2005/14252 ,  A61M2039/244 ,  A61M2039/2406 ,  A61M2039/248 ,  A61M2039/2426 ,  A61M2205/3561 ,  A61M2205/505 ,  A61M2205/7527 ,  A61M2205/7536 ,  A61M2209/045

Abstract: A drug delivery device includes a housing defining a shell and an inner volume, a container, a drive mechanism, a needle assembly, a fluid flow connection, and a backflow prevention mechanism. The container has an inner volume to contain a medicament to be administered to a user. The drive mechanism is at least partially disposed within the housing and exerts a force to urge the medicament out the container. The fluid flow connection is coupled to the container and the needle assembly and allows the medicament to flow from the container to the needle assembly to be administered. The backflow prevention mechanism is associated with at least one of the container, the fluid flow connection, or the needle assembly and includes at least one flow restrictor to restrict a fluid from flowing from the needle assembly to the container.

公开(公告)号：US20190275241A1

公开(公告)日：2019-09-12

申请号：US16297408

申请日：2019-03-08

Applicant: AMGEN INC.

Inventor： Lawrence S. Ring ,  Tohid Pirbodaghi ,  Samin Akbari ,  Daniel Eduardo Groszmann ,  Mehran Mojarrad ,  Mark Gordon ,  Mikhail Tikh ,  Jimmie L. Ward ,  Scott R. Gibson ,  Sheldon B. Moberg ,  Joshua Tamsky ,  Paul Faucher

IPC: A61M5/168 ,  A61M5/158 ,  A61M39/24

Abstract: A drug delivery device includes a housing defining a shell and an inner volume, a container, a drive mechanism, a needle assembly, a fluid flow connection, and a backflow prevention mechanism. The container has an inner volume to contain a medicament to be administered to a user. The drive mechanism is at least partially disposed within the housing and exerts a force to urge the medicament out the container. The fluid flow connection is coupled to the container and the needle assembly and allows the medicament to flow from the container to the needle assembly to be administered. The backflow prevention mechanism is associated with at least one of the container, the fluid flow connection, or the needle assembly and includes at least one flow restrictor to restrict a fluid from flowing from the needle assembly to the container.

公开(公告)号：US11369736B2

公开(公告)日：2022-06-28

申请号：US16485245

申请日：2018-02-13

Applicant: AMGEN INC.

Inventor： Erich Coiner ,  Paul Faucher ,  Adam B. McCullough ,  Antonio Ubach

IPC: A61M5/142 ,  A61M5/158 ,  A61B17/34

Abstract: An insertion mechanism for a wearable drug delivery device that deploys a small gauge flexible cannula with support of a coaxial rigid trocar or hollow needle. After insertion, the trocar or hollow needle is withdrawn leaving the cannula in place for drug delivery. The insertion mechanism may also include an insertion mechanism housing having a proximal and distal end, a manifold configured to fluidly connect the hollow interior of the cannula and the fluid pathway connector, and a manifold guide carrying the manifold and movable between a first position and a second position. A hub carries the trocar and is removably connected to the manifold guide. An insertion biasing member may be initially retained in an energized state between the proximal end of the insertion mechanism housing and the hub, and a retraction biasing member may be initially retained in an energized state between the hub and the manifold guide.