公开(公告)号：US20170114326A1

公开(公告)日：2017-04-27

申请号：US15402060

申请日：2017-01-09

Applicant: AMOREPACIFIC CORPORATION

Inventor： Joong Hyun SHIM ,  Seung Ha YANG ,  Tae Ryong LEE ,  Hak Hee KANG ,  Dong Wook SHIN

IPC: C12N5/0775 ,  C12Q1/68 ,  G01N33/74 ,  C12N5/071

CPC classification number: C12N5/0668 ,  A61K35/28 ,  A61K35/32 ,  A61K35/35 ,  A61K35/36 ,  C12N5/0625 ,  C12N2533/54 ,  C12Q1/6881 ,  C12Q2600/158 ,  G01N33/74 ,  G01N2333/475 ,  G01N2333/485 ,  G01N2333/49 ,  G01N2333/50

Abstract: Provided in the present invention are adult stem cells derived from human skin dermis, and a method for isolating same. Further provided in the present invention are osteoblastic cells and adipocytes differentiated from the adult stem cells derived from human skin dermis, and a differentiation method therefor. Further provided in the present invention is a composition for osteogenesis or lipogenesis containing the stem cells, osteoblastic cells, or adipocytes. The isolation method of the present invention enables the adult stem cells derived from human skin dermis to be obtained in an easy and simple manner at a high yield rate. Genes and growth factors which are specifically expressed in the adult stem cells derived from human skin dermis isolated using the method can be separated, identified, and used later.