Abstract:
The present disclosure discloses a method for improving the skin condition or anti-microorganisms or anti-oxidation using Lactobacillus sakei MD_honeysuckle (accession number: KCTC 12675BP) derived from Lonicera japonica Thunb. A composition containing the strain or a cultured product thereof, or an extract thereof as an active ingredient has superior DPPH radical scavenging activity and antimicrobial activity against pathogenic microorganisms, has a high total polyphenol content and is capable of inhibiting the growth of melanocytes. Accordingly, the composition of the present disclosure is effective in preventing aging, improving skin wrinkles, whitening skin, fighting against microorganisms and fighting against oxidation and can be widely used in cosmetic compositions, pharmaceutical compositions or health food compositions where such effects are required.
Abstract:
An artificial skin culture container according to the present invention can solve the problems of the contraction of the dermal layer of artificial skin and the detachment thereof from the culture container, which result from an interaction between collagen and fibroblasts existing in the dermal layer of artificial skin during the production of the artificial skin, by using agar and hydrophobically modifying a portion of the agar. Therefore, the use of the culture container enables to stably culture artificial skin and produce artificial skin similar to the human skin. In addition, the artificial skin culture container of the present invention comprises agar, and thus a culture solution can be supplied through a side portion as well as a lower portion of the culture container, which allows to effectively culture artificial skin.