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    METHOD FOR DETECTING A TARGET ANALYTE
    1.
    发明申请
    METHOD FOR DETECTING A TARGET ANALYTE 有权
    检测目标分析仪的方法

    公开(公告)号：US20150219643A1

    公开(公告)日：2015-08-06

    申请号：US14613649

    申请日：2015-02-04

    Applicant: Agency for Science, Technology and Research

    Inventor： Hong Yan Song ,  Ten It Wong ,  Anton Valentinovich Sadovoy ,  Xiaodong Zhou ,  Ping Bai ,  Lin Wu

    IPC: G01N33/543 ,  G01N21/65 ,  G01N33/58 ,  G01N33/553

    CPC classification number: G01N33/582 ,  G01N21/648 ,  G01N33/553 ,  G01N33/588

    Abstract: There is method for detecting the presence or absence of a target analyte in a sample comprising the steps of: allowing an inorganic fluorescent particle to conjugate with a detection biomolecule that is bound to said target analyte, if present in said sample, said target analyte additionally being bound by a capture biomolecule immobilized on or within a nanostructure; and detecting the fluorescence emitted by said inorganic fluorescent particle, said nanostructure being capable of generating a surface plasmon resonance effect when excited by a light source to substantially increase the fluorescence emitted by said inorganic fluorescent particle, wherein the detected fluorescence indicates the presence of said target analyte in said sample.

    Abstract translation: 存在用于检测样品中目标分析物的存在或不存在的方法，包括以下步骤：使无机荧光颗粒与结合到所述目标分析物的检测生物分子（如果存在于所述样品中）共轭，则所述靶分析物另外 被固定在纳米结构上或内部的捕获生物分子结合; 并且检测由所述无机荧光颗粒发射的荧光，所述纳米结构当被光源激发时能够产生表面等离子体共振效应，以显着增加由所述无机荧光颗粒发射的荧光，其中所检测的荧光指示存在所述目标 所述样品中的分析物。

    Sensor and method of detecting a target analyte
    2.
    发明授权
    Sensor and method of detecting a target analyte 有权
    传感器和检测目标分析物的方法

    公开(公告)号：US09157861B2

    公开(公告)日：2015-10-13

    申请号：US13665033

    申请日：2012-10-31

    Applicant: Agency for Science, Technology and Research

    Inventor： Ping Bai ,  Xiaodong Zhou ,  Lin Wu

    IPC: H01J40/14 ,  G01N21/64 ,  G01N21/62

    CPC classification number: G01N21/648 ,  G01N21/62

    Abstract: A sensor and a method of detecting a target analyte are provided. The sensor includes a substrate; a layer comprising a plurality of through holes, wherein the layer is disposed above the substrate; a first element configured to detect a target analyte; a second element that can produce a detectable signal; wherein the first element and the second element are configured to couple the target analyte between the first element and the second element.

    Abstract translation: 提供了一种传感器和检测目标分析物的方法。 传感器包括基板; 包括多个通孔的层，其中所述层设置在所述衬底上方; 构造成检测目标分析物的第一元件; 可产生可检测信号的第二个元件; 其中所述第一元件和所述第二元件被配置为在所述第一元件和所述第二元件之间耦合所述目标分析物。

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