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    IMPLANTABLE CORONARY PERFUSION MONITORING DEVICE
    1.
    发明申请
    IMPLANTABLE CORONARY PERFUSION MONITORING DEVICE 有权
    可植入冠脉灌注监测装置

    公开(公告)号：US20120083703A1

    公开(公告)日：2012-04-05

    申请号：US13265722

    申请日：2009-04-29

    申请人： Andreas Blomqvist ,  Karin Järverud ,  Michael Broomè

    发明人： Andreas Blomqvist ,  Karin Järverud ,  Michael Broomè

    IPC分类号： A61B5/02

    CPC分类号： A61B5/02158 ,  A61B5/02007 ,  A61B5/02028 ,  A61B5/02125 ,  A61B5/0295 ,  A61B5/053

    摘要： An implantable coronary perfusion monitoring device for in-vivo determination of a coronary perfusion index (CPI) indicative of the coronary perfusion of a heart has a time measurement unit to determine a blood pressure reflection wave measure t indicating the timely position in the heart cycle of the maximum of a reflected blood pressure wave and in a time period starting at a preset point of time in systole and ending at a local maximum of blood pressure following aortic valve closure and, a diastolic peak pressure measurement unit adapted to determine a diastolic peak blood pressure measure DPP related to diastolic aortic peak pressure and a systolic arterial pressure measurement unit adapted to determine a systolic arterial blood pressure measure SAP related to systolic arterial pressure, and a coronary perfusion index calculating unit adapted to determine said coronary perfusion index CPI as (t·DPP)/SAP.

    摘要翻译： 用于体内确定指示心脏冠状动脉灌注的冠状动脉灌注指数（CPI）的可植入冠状动脉灌注监测装置具有时间测量单元，以确定表示心脏周期中及时位置的血压反射波测量值 反射血压波的最大值和在收缩期的预设时间点开始并且在主动脉瓣关闭后结束于局部最大血压的时间段内，以及适于确定舒张峰血液的舒张峰值压力测量单元 压力测量与舒张性主动脉​​峰值压力相关的DPP和适于确定与收缩期动脉压相关的收缩期动脉血压测量SAP的收缩期动脉压测量单元，以及适于将所述冠状动脉灌注指数CPI确定为（t）的冠状动脉灌注指数计算单元 ·DPP）/ SAP。

    Implantable coronary perfusion monitoring device
    2.
    发明授权
    Implantable coronary perfusion monitoring device 有权
    植入式冠状动脉灌注监测装置

    公开(公告)号：US08690787B2

    公开(公告)日：2014-04-08

    申请号：US13265722

    申请日：2009-04-29

    申请人： Andreas Blomqvist ,  Karin Järverud ,  Michael Broomè

    发明人： Andreas Blomqvist ,  Karin Järverud ,  Michael Broomè

    IPC分类号： A61B5/02

    CPC分类号： A61B5/02158 ,  A61B5/02007 ,  A61B5/02028 ,  A61B5/02125 ,  A61B5/0295 ,  A61B5/053

    摘要： An implantable coronary perfusion monitoring device for in-vivo determination of a coronary perfusion index (CPI) indicative of the coronary perfusion of a heart has a time measurement unit to determine a blood pressure reflection wave measure t indicating the timely position in the heart cycle of the maximum of a reflected blood pressure wave and in a time period starting at a preset point of time in systole and ending at a local maximum of blood pressure following aortic valve closure and, a diastolic peak pressure measurement unit adapted to determine a diastolic peak blood pressure measure DPP related to diastolic aortic peak pressure and a systolic arterial pressure measurement unit adapted to determine a systolic arterial blood pressure measure SAP related to systolic arterial pressure, and a coronary perfusion index calculating unit adapted to determine said coronary perfusion index CPI as (t·DPP)/SAP.

    摘要翻译： 用于体内确定指示心脏冠状动脉灌注的冠状动脉灌注指数（CPI）的可植入冠状动脉灌注监测装置具有时间测量单元，以确定表示心脏周期中及时位置的血压反射波测量值 反射血压波的最大值和在收缩期的预设时间点开始并且在主动脉瓣关闭后结束于局部最大血压的时间段内，以及适于确定舒张峰血液的舒张峰值压力测量单元 压力测量与舒张性主动脉​​峰值压力相关的DPP和适于确定与收缩期动脉压相关的收缩期动脉血压测量SAP的收缩期动脉压测量单元，以及适于将所述冠状动脉灌注指数CPI确定为（t）的冠状动脉灌注指数计算单元 ·DPP）/ SAP。

    IMPLANTABLE HEART ANALYZING DEVICE, SYSTEM AND METHOD
    3.
    发明申请
    IMPLANTABLE HEART ANALYZING DEVICE, SYSTEM AND METHOD 审中-公开
    可植入心脏分析装置，系统和方法

    公开(公告)号：US20100099994A1

    公开(公告)日：2010-04-22

    申请号：US12528160

    申请日：2007-02-28

    申请人： Nils Holmström ,  Andreas Blomqvist ,  Berit Larsson ,  Karin Järverud ,  Sven-Erik Hedberg

    发明人： Nils Holmström ,  Andreas Blomqvist ,  Berit Larsson ,  Karin Järverud ,  Sven-Erik Hedberg

    IPC分类号： A61B5/02

    CPC分类号： A61B5/1107 ,  A61B5/0051 ,  A61B5/4519 ,  A61B5/6869 ,  A61N1/36578

    摘要： An implantable heart analyzing device has a housing and a control circuit located within said housing. The control circuit generates an output signal adapted to actuate an activator, which is able to make a wall of the heart deflect or vibrate. The control circuit also communicates with a sensor, which can be identical with the activator, with which the movement of the heart wall can be sensed. The control circuit executes a procedure that involves the generation of an output signal and sensing a corresponding sensor signal, and to be able to derive information concerning the tension of the heart wall. An implantable heart analyzing includes the aforementioned heart analyzing device, as well as the activator and the sensor. The heart analyzing device and the system implement a method that results in generation of the aforementioned information concerning the tension of the heart wall.

    摘要翻译： 可植入心脏分析装置具有壳体和位于所述壳体内的控制电路。 控制电路产生适于致动激活器的输出信号，其能够使心脏的壁发生偏转或振动。 控制电路还与传感器通信，传感器可以与激活器相同，通过该传感器可以感测心脏壁的移动。 控制电路执行涉及生成输出信号并感测相应的传感器信号的过程，并且能够得出关于心壁的张力的信息。 可植入心脏分析包括上述心脏分析装置，以及活化剂和传感器。 心脏分析装置和系统实施导致产生上述关于心脏壁张力的信息的方法。

    IMPLANTABLE HEART STIMULATOR DETERMINING LEFT VENTRICULAR SYSTOLIC PRESSURE
    7.
    发明申请
    IMPLANTABLE HEART STIMULATOR DETERMINING LEFT VENTRICULAR SYSTOLIC PRESSURE 审中-公开
    可植入心脏刺激器确定左心室舒张压

    公开(公告)号：US20110046691A1

    公开(公告)日：2011-02-24

    申请号：US12990136

    申请日：2008-06-18

    申请人： Anders Björling ,  Andreas Blomqvist ,  Karin Järverud

    发明人： Anders Björling ,  Andreas Blomqvist ,  Karin Järverud

    IPC分类号： A61N1/36

    CPC分类号： A61B5/0215 ,  A61B5/053 ,  A61N1/36521

    摘要： An implantable heart stimulator has an impedance measurement a cardiogenic impedance waveform using an impedance configuration arranged to measure myocardial contractility of the heart. The heart stimulator further has a calculating unit that calculates an estimate value being related to at least two impedance values of the waveform, or of an average waveform of several consecutive waveforms, during a predetermined time period of the waveform, or average waveform, the calculated estimate value being an estimate of the left ventricular (LV) systolic pressure.

    摘要翻译： 可植入心脏刺激器具有使用布置成测量心脏的心肌收缩力的阻抗配置的心源阻抗波形的阻抗测量。 心脏刺激器还具有计算单元，该计算单元在波形的预定时间段期间，计算与波形的至少两个阻抗值或几个连续波形的平均波形有关的估计值，或者计算出平均波形 估计值是左心室（LV）收缩压的估计值。

    METHOD, IMPLANTABLE MEDICAL DEVICE, AND SYSTEM FOR DETERMINING THE CONDITION OF A HEART VALVE (As Amended)
    9.
    发明申请
    METHOD, IMPLANTABLE MEDICAL DEVICE, AND SYSTEM FOR DETERMINING THE CONDITION OF A HEART VALVE (As Amended) 有权
    方法，可植入医疗装置和用于确定心脏瓣膜状态的系统（如修改）

    公开(公告)号：US20110237968A1

    公开(公告)日：2011-09-29

    申请号：US13131527

    申请日：2008-11-28

    申请人： Andreas Blomqvist ,  Karin Järverud

    发明人： Andreas Blomqvist ,  Karin Järverud

    IPC分类号： A61B5/0402

    CPC分类号： A61B5/686 ,  A61B5/02028 ,  A61B5/04012 ,  A61B5/042 ,  A61B5/0432 ,  A61N1/3627 ,  A61N1/36521 ,  A61N1/368 ,  A61N1/3682 ,  A61N1/3684 ,  A61N1/3702

    摘要： An implantable medical device has an impedance processor that determines impedance data reflective of the transvalvular impedance of a heart valve of a heart during a heart cycle. The determined impedance data are processed by a representation processor that estimates diastolic and systolic transvalvular impedance representations. A condition processor determines the presence of any heart valve malfunction, such as valve regurgitation and/or stenosis, of the heart valve based on the estimated diastolic and systolic transvalvular impedance representations.

    摘要翻译： 可植入医疗装置具有阻抗处理器，其确定在心脏周期期间反映心脏心脏瓣膜的跨瓣阻抗的阻抗数据。 所确定的阻抗数据由估计舒张期和收缩期跨瓣阻抗表示的表示处理器处理。 状态处理器基于估计的舒张期和收缩期跨瓣阻抗表示来确定心脏瓣膜的任何心脏瓣膜故障（例如瓣膜反流和/或狭窄）的存在。

    Late potential detection
    10.
    发明授权
    Late potential detection 有权
    晚期电位检测

    公开(公告)号：US08700139B2

    公开(公告)日：2014-04-15

    申请号：US13380933

    申请日：2009-06-26

    申请人： Andreas Blomqvist

    发明人： Andreas Blomqvist

    IPC分类号： A61B5/04

    CPC分类号： A61B5/0452 ,  A61B5/0006 ,  A61B5/002 ,  A61B5/0031 ,  A61B5/0422 ,  A61B5/686 ,  A61B5/7242 ,  A61B5/7275 ,  A61B2505/07 ,  A61N1/362 ,  G06F19/00

    摘要： A late potential detecting system has an implantable medical device connected to at least one cardiac lead having implantable electrodes positioned at different sites of a ventricle myocardium. A sampling unit of the implantable medical device records electrogram samples for the different implantable electrodes to get different sample sets. The electrogram samples of the sample sets are time synchronized and magnitude potential representations of the potential data of the electrogram samples are determined. The magnitude potential representations of the time synchronized electrogram samples are then co-processed and used for determining a parameter that is indicative of any late potentials of the monitored ventricle.

    摘要翻译： 晚期电位检测系统具有连接到至少一个具有位于心室心肌不同部位的可植入电极的心脏引线的可植入医疗装置。 可植入医疗装置的采样单元记录不同可植入电极的电描记图样品以获得不同的样品组。 样本集的电描记图样本是时间同步的，并且确定电描记图样本的潜在数据的幅度电位表示。 然后对时间同步电描记图样本的幅度电位表示进行协处理，并用于确定指示所监测的心室的任何后期电位的参数。