公开(公告)号：US20180353875A1

公开(公告)日：2018-12-13

申请号：US16060043

申请日：2016-12-12

Applicant: BASF SE

Inventor： Pedro Sa Gomes ,  Bastiaan Bram Pieter Staal ,  Felicitas Guth ,  Nigel A. Langley

IPC: B01D15/34 ,  B01D15/18 ,  C08G65/30 ,  C08G65/08

CPC classification number: B01D15/34 ,  B01D15/1807 ,  B01D15/1821 ,  B01D15/1871 ,  B01D15/1892 ,  C08G65/08 ,  C08G65/30 ,  C08G2650/58

Abstract: A process for purification of polyether block copolymers comprising polyoxyethylene and polyoxypropylene moieties using sequential multi-column size exclusion chromatography apparatus operated as a counter current moving bed wherein a process cycle comprises the steps of.

公开(公告)号：US20210163879A1

公开(公告)日：2021-06-03

申请号：US16772865

申请日：2018-12-07

Applicant: BASF SE

Inventor： Felicitas Guth ,  Karl Kolter ,  Nigel A. Langley ,  Kerri Gaumer Freidl ,  Kristina Brueggemann

IPC: C12N5/00

Abstract: A method for stabilizing cells in cell culture production, the method comprising culturing a cell line capable of expressing proteins in cell culture media, and supplementing said cell culture media with a graft polymer in which N-vinyl caprolactam and vinyl acetate moieties are grafted on a polyethylene glycol backbone.