公开(公告)号：US20140364623A1

公开(公告)日：2014-12-11

申请号：US14371755

申请日：2012-12-13

Applicant: BASF SE

Inventor： Michael Keil ,  Wolfgang Reichert ,  Christopher Koradin ,  Yüksel Battal

IPC: C07D231/12 ,  C07C211/48

CPC classification number: C07D231/12 ,  C07C211/48

Abstract: The present invention relates to a novel process for preparing acetanilides of the formula (I) by reacting a 2-halo-N-halomethylacetanilide of the formula (II) with an azole of the formula (III) H-A  (III) wherein the substituents R, R1, R2, R3, R4, A, X and X1 in the formulae (I), (II) and (III) have the meanings as indicated in the description.

Abstract translation: 本发明涉及一种通过使式（II）的2-卤代-N-卤代甲基乙酰苯胺与式（III）的唑（III）的反应制备式（I）的乙酰苯胺的新方法，其中取代基R 式（I），（II）和（III）中的R 1，R 2，R 3，R 4，A，X和X 1具有如说明书中所示的含义。

公开(公告)号：US09598428B2

公开(公告)日：2017-03-21

申请号：US14760302

申请日：2014-01-15

Applicant: BASF SE

Inventor： Melanie Bonnekessel ,  Wolfgang Reichert ,  Ralf Hoock ,  Thomas Kaeding ,  Christopher Koradin ,  Andreas Pletsch ,  Manfred Ehresmann ,  Hartwig Schroeder

IPC: A01N43/90 ,  A01N53/00 ,  C07D493/04

CPC classification number: C07D493/04 ,  A01N43/90 ,  A01N53/00

Abstract: The present invention relates to a method for preparing the pyripyropene compound of the formula (I) which method comprises the following steps: i) subjecting a pyripyropene compound of formula Pyripyropene A to an alkaline hydrolysis to yield a 1,7,11 -trideacetylpyripyropene A, ii) reacting 1,7,11-trideacetylpyripyropene A obtained in step i) with cyclopropane carbonyl chloride to yield a raw product containing the pyripyropene compound of formula (I); iii) subjecting the raw product of step ii) to crystallization to yield a crystalline pyripyropene compound of formula (I) and a mother liquor; and iv) recycling the mother liquor or a pyripyropene compound containing fraction thereof to the alkaline hydrolysis of step i).