公开(公告)号：US10150777B2

公开(公告)日：2018-12-11

申请号：US14778788

申请日：2014-03-03

Applicant: BASF SE

Inventor： Burkhard Ernst ,  Manfred Ehresmann ,  Christopher Koradin ,  Andreas Pletsch ,  Melanie Bonnekessel ,  Thomas Kaeding ,  Karin Schein-Albrecht ,  Stefanie Demming ,  Franz Weber ,  Wolfgang Siegel ,  Hartwig Schroeder ,  Stephan Freyer ,  Peter Oedman

IPC: C07D493/04 ,  C12P17/18 ,  A01N43/40

Abstract: The invention pertains to processes to produce dry biomass of pyripyropene producer organisms, processes to obtain pyripyropenes from such dry biomass, as well as to processes to produce compounds of Formula III and/or Formula IV and/or Formula V from the pyripyropenes obtained from the dry biomass. The invention does further pertain to the dry biomass itself, as well as processes using said dry biomass to obtain pyripyropenes for the production of compounds of Formula III and/or Formula IV and/or Formula V, including processes using said dry biomass to obtain pyripyropenes or compounds of Formula III and/or Formula IV and/or Formula V in order to produce pest control compositions, in particular insecticides, comprising such compounds.

公开(公告)号：US09988333B2

公开(公告)日：2018-06-05

申请号：US15311951

申请日：2015-05-18

Applicant: BASF SE

Inventor： Andreas Pletsch ,  Nicole Holub ,  Thomas Ulrich ,  Petr Kvita ,  Laurent Cavin

IPC: C07C37/01 ,  C07C51/353 ,  C07C37/045 ,  C07C37/76 ,  C07C241/02 ,  C07C209/36 ,  C07C201/08 ,  C07C51/00 ,  C07C67/00

CPC classification number: C07C51/353 ,  C07C37/045 ,  C07C37/76 ,  C07C51/00 ,  C07C51/15 ,  C07C51/367 ,  C07C67/00 ,  C07C201/08 ,  C07C209/365 ,  C07C241/02 ,  C07C39/30 ,  C07C65/05 ,  C07C65/21

Abstract: The present invention relates to a process for reacting chemical compounds comprising the step of reacting a compound of formula (IV) wherein Hal is independently selected from Cl or Br, and X− is a monovalent anion, in the presence of an inorganic acid, wherein the aqueous inorganic acid has a concentration of at least about 60%, at a temperature of about 140° C. to about 250° C., to obtain a compound of formula (V) wherein Hal is as defined above.

公开(公告)号：US09598428B2

公开(公告)日：2017-03-21

申请号：US14760302

申请日：2014-01-15

Applicant: BASF SE

Inventor： Melanie Bonnekessel ,  Wolfgang Reichert ,  Ralf Hoock ,  Thomas Kaeding ,  Christopher Koradin ,  Andreas Pletsch ,  Manfred Ehresmann ,  Hartwig Schroeder

IPC: A01N43/90 ,  A01N53/00 ,  C07D493/04

CPC classification number: C07D493/04 ,  A01N43/90 ,  A01N53/00

Abstract: The present invention relates to a method for preparing the pyripyropene compound of the formula (I) which method comprises the following steps: i) subjecting a pyripyropene compound of formula Pyripyropene A to an alkaline hydrolysis to yield a 1,7,11 -trideacetylpyripyropene A, ii) reacting 1,7,11-trideacetylpyripyropene A obtained in step i) with cyclopropane carbonyl chloride to yield a raw product containing the pyripyropene compound of formula (I); iii) subjecting the raw product of step ii) to crystallization to yield a crystalline pyripyropene compound of formula (I) and a mother liquor; and iv) recycling the mother liquor or a pyripyropene compound containing fraction thereof to the alkaline hydrolysis of step i).