Gadolinium contrast agents, scavenging methods, and scavenging system

    公开(公告)号:US11224666B2

    公开(公告)日:2022-01-18

    申请号:US16276169

    申请日:2019-02-14

    Abstract: A functional gadolinium contrast agent comprising a gadolinium cation and a ligand secured to the gadolinium cation is disclosed, the ligand comprising a reactive group capable of bonding to a capture substrate. A method of removing gadolinium contrast agents from a patient is disclosed, the method comprising providing a gadolinium contrast agent containing a reactive group; providing a capture substrate for insertion into a patient's bloodstream; administering the gadolinium contrast agent to the patient; conducting a magnetic resonance imaging procedure; and sequestering the gadolinium contrast agent on the capture substrate. A system for removing gadolinium contrast agents is also disclosed.

    TREATMENT OF VASCULAR LESIONS
    3.
    发明申请

    公开(公告)号:US20190282250A1

    公开(公告)日:2019-09-19

    申请号:US16351186

    申请日:2019-03-12

    Abstract: An ultrasound catheter is adapted for placement within a blood vessel having a vessel wall and is adapted for treating a vascular lesion within or adjacent the vessel wall. The ultrasound catheter includes an elongate shaft extending from a distal region to a proximal region and an ultrasound transducer that is disposed within the distal region of the elongate shaft, the ultrasound transducer adapted to impart near-field, acoustic pressure waves upon the vascular lesion in order to mechanically modify the vascular lesion.

    Balloon-based intravascular ultrasound system for treatment of vascular lesions

    公开(公告)号:US11103262B2

    公开(公告)日:2021-08-31

    申请号:US16351183

    申请日:2019-03-12

    Abstract: An ultrasound catheter may be adapted for placement within a blood vessel having a vessel wall for treating a vascular lesion within or adjacent the vessel wall. The ultrasound catheter includes an elongate shaft extending from a distal region to a proximal region and an ultrasound transducer that is disposed relative to the distal region of the elongate shaft and is adapted to impart near-field acoustic pressure waves upon the vascular lesion in order to mechanically modify the vascular lesion. An inflatable balloon is disposed about the ultrasound transducer and is coupled to the elongate shaft, the inflatable balloon having a collapsed configuration suitable for advancing the ultrasound catheter through a patient's vasculature and an expanded configuration suitable for anchoring the ultrasound catheter in position relative to a treatment site.

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