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公开(公告)号：US11826020B2
公开(公告)日：2023-11-28
申请号：US16834555
申请日：2020-03-30
Inventor： James P. Rohl , David R. Wulfman , Brian T. Berg , Joseph Thomas Delaney, Jr. , Brian J. Tischler , Peter M. Pollak , Harold M. Burkhart , Joseph A. Dearani , Sorin V. Pislaru
IPC: A61B17/04 , A61F2/24 , A61B17/00 , A61M25/10 , A61B1/00 , A61B1/018 , A61B1/05 , A61B1/06 , A61B1/313 , A61B8/12 , A61B17/064 , A61B17/122 , A61B17/068 , A61B17/128 , A61B17/06 , A61B90/30 , A61B90/00
CPC classification number: A61B1/00082 , A61B1/00087 , A61B1/00148 , A61B1/018 , A61B1/05 , A61B1/0676 , A61B1/3137 , A61B8/12 , A61B17/0401 , A61B17/0469 , A61B17/0644 , A61B17/122 , A61F2/2466 , A61M25/1029 , A61B17/068 , A61B17/1227 , A61B17/1285 , A61B2017/00526 , A61B2017/00783 , A61B2017/00902 , A61B2017/00907 , A61B2017/0406 , A61B2017/048 , A61B2017/0409 , A61B2017/0472 , A61B2017/06042 , A61B2017/0649 , A61B2090/306 , A61B2090/309 , A61B2090/3612 , A61F2220/0008 , A61F2220/0016 , A61M25/1002 , A61M2025/105 , A61M2025/1075 , A61M2025/1088
Abstract: A direct visualization catheter includes an elongate shaft defining a lumen and having a distal end portion and a proximal end portion and a transparent balloon attached to the distal end portion of the shaft. The balloon includes a first layer comprising a thermoset polymer and a plurality of polymeric fibers at least partially embedded in the thermoset polymer and a second layer disposed on the first layer and comprising a hydrogel.
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公开(公告)号：US11213596B2
公开(公告)日：2022-01-04
申请号：US16276174
申请日：2019-02-14
Applicant: Boston Scientific Scimed, Inc.
Inventor： Joseph Thomas Delaney, Jr. , Douglas Dean Pagoria , Richard Lee Tadsen , Andrew J. Ro , Joel T. Eggert , Douglas Pennington , Paul Sorajja , Sarah Melissa Gruba , Tatyana Dyndikova
Abstract: An imaging contrast composition comprising an iodinated contrast agent and a ligand secured to the iodinated contrast agent is disclosed, the ligand comprising a reactive group capable of bonding to a capture substrate. A method of removing iodinated radiocontrast agents from a patient is disclosed, the method comprising providing an iodinated radiocontrast agent containing a reactive group; providing a capture substrate for insertion into a patient's bloodstream; administering the iodinated radiocontrast agent to the patient; conducting procedure CT scan or procedure using fluoroscopy; and sequestering the iodinated radiocontrast agent on the capture substrate.
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公开(公告)号：US10285569B2
公开(公告)日：2019-05-14
申请号：US15003924
申请日：2016-01-22
Inventor： James P. Rohl , David R. Wulfman , Brian T. Berg , Joseph Thomas Delaney, Jr. , Brian J. Tischler , Peter M. Pollak , Harold M. Burkhart , Joseph A. Dearani , Sorin V. Pislaru
IPC: A61B17/04 , A61B17/12 , A61B1/00 , A61B1/018 , A61B1/05 , A61B1/313 , A61B17/122 , A61B1/06 , A61B8/12 , A61B17/064 , A61B17/00 , A61M25/10 , A61B90/30 , A61B90/00 , A61B17/128 , A61B17/068 , A61B17/06
Abstract: A direct visualization catheter includes an elongate shaft defining a lumen and having a distal end portion and a proximal end portion and a transparent balloon attached to the distal end portion of the shaft. The balloon includes a first layer comprising a thermoset polymer and a plurality of polymeric fibers at least partially embedded in the thermoset polymer and a second layer disposed on the first layer and comprising a hydrogel.
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公开(公告)号：US10219677B2
公开(公告)日：2019-03-05
申请号：US15003924
申请日：2016-01-22
Inventor： James P. Rohl , David R. Wulfman , Brian T. Berg , Joseph Thomas Delaney, Jr. , Brian J. Tischler , Peter M. Pollak , Harold M. Burkhart , Joseph A. Dearani , Sorin V. Pislaru
IPC: A61B17/04 , A61B17/12 , A61B1/00 , A61B1/018 , A61B1/05 , A61B1/313 , A61B17/122 , A61B1/06 , A61B8/12 , A61B17/064 , A61B17/00 , A61M25/10 , A61B90/30 , A61B90/00 , A61B17/128 , A61B17/068 , A61B17/06
Abstract: A direct visualization catheter includes an elongate shaft defining a lumen and having a distal end portion and a proximal end portion and a transparent balloon attached to the distal end portion of the shaft. The balloon includes a first layer comprising a thermoset polymer and a plurality of polymeric fibers at least partially embedded in the thermoset polymer and a second layer disposed on the first layer and comprising a hydrogel.
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公开(公告)号：US12115275B2
公开(公告)日：2024-10-15
申请号：US17179971
申请日：2021-02-19
Applicant: Boston Scientific Scimed, Inc.
Inventor： Joseph Thomas Delaney, Jr. , Patrick Willoughby , David Robert Wulfman , Andrew J. Ro , Niraj Gurung
CPC classification number: A61L27/16 , A61L27/48 , C08J3/246 , C08L53/00 , D01D5/0023 , D01D5/003 , D01D5/0985 , A61L2430/20 , C08J2323/18 , C08J2323/22 , C08J2337/00 , C08J2479/02 , C08L2203/02 , D10B2509/06 , A61L27/48 , C08L23/22
Abstract: Aspects herein relate to biocompatible polyisobutylene-fiber composite materials and related methods. In one aspect a biocompatible composite material is included. The biocompatible composite material can include a network of fibers comprising one or more polymers to form a substrate and a continuous polyisobutylene matrix that is non-porous and completely surrounds the electrospun fibers. Other aspects are included herein.
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Patent Agency Ranking
公开(公告)号：US10299915B2
公开(公告)日：2019-05-28
申请号：US15082293
申请日：2016-03-28
Applicant: Boston Scientific SciMed, Inc.
Inventor： Peter G. Edelman , Mark W. Boden , Joseph Thomas Delaney, Jr.
Abstract: A prosthetic heart valve includes a plurality of synthetic polymeric leaflets. Each leaflet has a base polymer and a polymer coating at least partially disposed over the base polymer, wherein the polymer coating includes polymerized units of a monomer comprising a zwitterionic group when the polymer coating is exposed to an aqueous environment at a pH of about 7.4.
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7.发明申请公开(公告)号：US20250136760A1
公开(公告)日：2025-05-01
申请号：US18934579
申请日：2024-11-01
Applicant: Boston Scientific Scimed, Inc.
Inventor： Nicolas Ball-Jones , Rick Dorn , Cristian Parisi , Yen-Hao Hsu , Joseph Thomas Delaney, Jr. , Sasha Viola Rios , Kyle A. Kalstabakken
IPC: C08G73/02 , A61K9/06 , A61K31/785
Abstract: In some aspects, the present disclosure pertains to amino-acid-based polyamine compounds that are formed by a ring-opening reaction of two or more amino acid N-carboxyanhydride molecules with a polyol having two or more hydroxyl groups under acid catalyzed conditions. In some aspects, the present disclosure pertains to amino-acid-based polyamine compounds that are formed by ester coupling reaction of two or more amine-protected amino acid molecules with a polyol having two or more hydroxyl groups in the presence of an ester coupling agent. In some aspects, the present disclosure pertains to amino-alcohol-based polyamine compounds that are formed by an ester coupling reaction of two or more amine-protected amino alcohol molecules having one or more amino groups and a single hydroxyl group with a polycarboxylic acid compound having two or more carboxyl groups in the presence of an ester coupling agent.
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公开(公告)号：US20240075190A1
公开(公告)日：2024-03-07
申请号：US18449907
申请日：2023-08-15
Applicant: Boston Scientific Scimed, Inc.
Inventor： Yen-Hao Hsu , Joseph Thomas Delaney, Jr. , Cristian Parisi
CPC classification number: A61L27/52 , C08L79/02 , C08L2203/02 , C08L2312/00
Abstract: In some aspects, the present disclosure pertains to systems for forming a hydrogel that comprise (a) an iodinated polyamino compound and (b) a reactive multi-arm polymer that comprises a plurality of hydrophilic polymer arms having unsaturated end groups that are reactive with amino groups of the iodinated polyamino compound. Other aspects of the present disclosure pertain to medical hydrogels that are formed by crosslinking the iodinated polyamino compound and the reactive multi-arm polymer of such systems. Further aspects of the present disclosure pertain to medical procedures that can be performed using such systems.
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公开(公告)号：US11304798B2
公开(公告)日：2022-04-19
申请号：US16413104
申请日：2019-05-15
Applicant: Boston Scientific Scimed, Inc.
Inventor： David Robert Wulfman , Thomas A. Wrobel , Crystal Marie Anderson-Cunanan , Joseph Thomas Delaney, Jr. , Patrick Willoughby , Mark W. Boden , Peter G. Edelman , Michael Eppihimer
Abstract: A prosthetic heart valve leaflet includes a plurality of electrospun fibers at least partially embedded in a polymer matrix. The plurality of fibers includes a first polyisobutylene urethane copolymer having a first predetermined weight average percentage of hard segment portions and the polymer matrix includes a second polyisobutylene urethane copolymer having a second predetermined weight average percentage of the hard segment portions, wherein the first predetermined weight average percentage of the hard segment portions is greater than the second predetermined weight average percentage of the hard segment portions.
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公开(公告)号：US11224666B2
公开(公告)日：2022-01-18
申请号：US16276169
申请日：2019-02-14
Applicant: Boston Scientific Scimed, Inc.
Inventor： Joseph Thomas Delaney, Jr. , Douglas Dean Pagoria , Douglas Pennington , Paul Sorajja
Abstract: A functional gadolinium contrast agent comprising a gadolinium cation and a ligand secured to the gadolinium cation is disclosed, the ligand comprising a reactive group capable of bonding to a capture substrate. A method of removing gadolinium contrast agents from a patient is disclosed, the method comprising providing a gadolinium contrast agent containing a reactive group; providing a capture substrate for insertion into a patient's bloodstream; administering the gadolinium contrast agent to the patient; conducting a magnetic resonance imaging procedure; and sequestering the gadolinium contrast agent on the capture substrate. A system for removing gadolinium contrast agents is also disclosed.
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