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公开(公告)号：US20160257645A1
公开(公告)日：2016-09-08
申请号：US15031352
申请日：2014-10-23
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Annapurna Pendri , Guo Li , John A. Bender , Zhong Yang , Alan Xiangdong Wang , Brett R. Beno , Robert A. Fridell , Makonen Belema , Nicholas A. Meanwell , Robert G. Gentles
IPC: C07C311/58 , C07D317/66 , C07D409/12 , C07D405/12 , C07D317/46 , C07D407/12 , C07D271/06 , C07D307/38 , C07D333/18 , C07D231/12 , C07D333/54 , C07D209/10 , C07D333/28 , C07D261/08 , C07D215/08 , C07D209/08 , C07D277/82 , C07D495/04 , C07D491/08 , C07D205/04 , C07D401/04 , C07D213/56 , C07D249/08 , C07D265/36
CPC classification number: C07C311/58 , C07C2601/08 , C07C2601/14 , C07C2602/08 , C07D205/04 , C07D209/08 , C07D209/10 , C07D213/56 , C07D215/08 , C07D231/12 , C07D249/08 , C07D261/08 , C07D265/36 , C07D271/06 , C07D277/82 , C07D307/38 , C07D317/46 , C07D317/66 , C07D333/18 , C07D333/28 , C07D333/54 , C07D401/04 , C07D405/12 , C07D407/12 , C07D409/12 , C07D491/08 , C07D495/04
Abstract: Compounds of Formula I with activity against HIV, including pharmaceutical compositions and methods for using these compounds in treating human immunodeficiency virus (HIV) infection, are set forth: Formula: (I)
Abstract translation: 阐述了具有抗HIV活性的式I化合物，包括药物组合物和使用这些化合物治疗人类免疫缺陷病毒（HIV）感染的方法：式（I）
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公开(公告)号：US20170355689A1
公开(公告)日：2017-12-14
申请号：US15689286
申请日：2017-08-29
Applicant: Bristol-Myers Squibb Company
Inventor： RICO LAVOIE , John A. Bender , Zhong Yang , Makonen Belema , Omar D. Lopez , Qi Chen , Gan Wang , Piyasena Hewawasam
IPC: C07D309/06 , C07D487/04 , C07D403/10 , A61K31/4184 , A61K31/4375 , A61K31/498 , A61K31/4545 , A61K31/5377 , C07D401/14 , C07D403/14 , C07D405/14 , A61K31/437 , A61K31/4709 , A61K45/06 , C07D413/14 , C07D471/04 , A61K31/4178 , A61K31/4985
CPC classification number: C07D309/06 , A61K31/4178 , A61K31/4184 , A61K31/437 , A61K31/4375 , A61K31/4545 , A61K31/4709 , A61K31/498 , A61K31/4985 , A61K31/5377 , A61K45/06 , C07D401/14 , C07D403/10 , C07D403/14 , C07D405/14 , C07D413/14 , C07D471/04 , C07D487/04
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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公开(公告)号：US20130115193A1
公开(公告)日：2013-05-09
申请号：US13672266
申请日：2012-11-08
Applicant: Bristol-Myers Squibb Company
Inventor： Rico Lavoie , John A. Bender , Zhong Yang , Makonen Belema , Omar D. Lopez , Qi Chen , Gan Wang , Piyasena Hewawasam
IPC: C07D403/14 , A61K31/4545 , C07D401/14 , A61K31/437 , C07D471/04 , A61K31/4985 , C07D487/04 , C07D405/14 , A61K31/498 , A61K31/4178 , A61K31/4375 , A61K31/4709 , A61K31/5377 , C07D413/14 , C07D403/10 , A61K45/06 , A61K31/4184
CPC classification number: C07D309/06 , A61K31/4178 , A61K31/4184 , A61K31/437 , A61K31/4375 , A61K31/4545 , A61K31/4709 , A61K31/498 , A61K31/4985 , A61K31/5377 , A61K45/06 , C07D401/14 , C07D403/10 , C07D403/14 , C07D405/14 , C07D413/14 , C07D471/04 , C07D487/04
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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公开(公告)号：US20150252028A1
公开(公告)日：2015-09-10
申请号：US14434049
申请日：2012-10-24
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Jeffrey Lee Romine , Zhong Yang , Gan Wang , Van N. Nguyen , John A. Bender , Denis R. St. Laurent , Makonen Belema
IPC: C07D405/14 , A61K45/06 , A61K31/4178
CPC classification number: A61K31/4178 , A61K45/06 , C07D403/14 , C07D405/14
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
Abstract translation: 本公开涉及用于治疗丙型肝炎病毒（HCV）感染的化合物，组合物和方法。 还公开了含有这些化合物的药物组合物和使用这些化合物治疗HCV感染的方法。
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公开(公告)号：US09776981B2
公开(公告)日：2017-10-03
申请号：US14807084
申请日：2015-07-23
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Rico Lavoie , John A. Bender , Zhong Yang , Makonen Belema , Omar D. Lopez , Qi Chen , Gan Wang , Piyasena Hewawasam
IPC: C07D487/04 , C07D309/06 , C07D401/14 , C07D403/14 , C07D471/04 , A61K31/4178 , A61K31/4184 , A61K31/437 , A61K31/4375 , A61K31/4545 , A61K31/4709 , A61K31/498 , A61K31/4985 , A61K31/5377 , A61K45/06 , C07D403/10 , C07D405/14 , C07D413/14
CPC classification number: C07D309/06 , A61K31/4178 , A61K31/4184 , A61K31/437 , A61K31/4375 , A61K31/4545 , A61K31/4709 , A61K31/498 , A61K31/4985 , A61K31/5377 , A61K45/06 , C07D401/14 , C07D403/10 , C07D403/14 , C07D405/14 , C07D413/14 , C07D471/04 , C07D487/04
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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Patent Agency Ranking
公开(公告)号：US20150197499A1
公开(公告)日：2015-07-16
申请号：US14668090
申请日：2015-03-25
Applicant: Bristol-Myers Squibb Company
Inventor： Rico Lavoie , John A. Bender , Zhong Yang , Makonen Belema , Omar D. Lopez , Qi Chen , Gan Wang , Piyasena Hewawasam
IPC: C07D309/06
CPC classification number: C07D309/06 , A61K31/4178 , A61K31/4184 , A61K31/437 , A61K31/4375 , A61K31/4545 , A61K31/4709 , A61K31/498 , A61K31/4985 , A61K31/5377 , A61K45/06 , C07D401/14 , C07D403/10 , C07D403/14 , C07D405/14 , C07D413/14 , C07D471/04 , C07D487/04
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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公开(公告)号：US09561212B2
公开(公告)日：2017-02-07
申请号：US15227709
申请日：2016-08-03
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Jeffrey Lee Romine , Zhong Yang , Gan Wang , Van N. Nguyen , John A. Bender , Denis R. St. Laurent , Makonen Belema
IPC: C07D405/14 , A61K45/06 , A61K31/4178 , C07D403/14
CPC classification number: A61K31/4178 , A61K45/06 , C07D403/14 , C07D405/14
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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公开(公告)号：US20160338999A1
公开(公告)日：2016-11-24
申请号：US15227709
申请日：2016-08-03
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Jeffrey Lee Romine , Zhong Yang , Gan Wang , Van N. Nguyen , John A. Bender , Denis R. St. Laurent , Makonen Belema
IPC: A61K31/4178 , C07D403/14 , C07D405/14 , A61K45/06
CPC classification number: A61K31/4178 , A61K45/06 , C07D403/14 , C07D405/14
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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9.发明申请4,4'-BIPHENYLDIYL-BIS-(1 H-IMIDAZOLYL) DERIVATIVES AS HEPATITIS HCV INHIBITORS 审中-公开作为丙型肝炎病毒抑制剂的4,4'-联苯二甲酸二（B） - （1H-咪唑啉）衍生物公开(公告)号：US20160311806A1
公开(公告)日：2016-10-27
申请号：US15100681
申请日：2014-12-02
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： John A. Bender , Zhong Yang , Makonen Belema
IPC: C07D405/14 , A61K45/06 , A61K31/4178
CPC classification number: C07D405/14 , A61K31/4178 , A61K45/06
Abstract: The present disclosure relates to compounds of formula (I), pharmaceutical compositions and use thereof in treatment of hepatitis C virus (HCV) infection.
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公开(公告)号：US20150322048A1
公开(公告)日：2015-11-12
申请号：US14807084
申请日：2015-07-23
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Rico Lavoie , John A. Bender , Zhong Yang , Makonen Belema , Omar D. Lopez , Qi Chen , Gan Wang , Piyasena Hewawasam
IPC: C07D403/14 , A61K45/06 , A61K31/4178 , A61K31/4545 , C07D471/04 , A61K31/437 , C07D487/04 , A61K31/4985 , C07D405/14 , C07D401/14 , A61K31/4709 , A61K31/498 , A61K31/4375 , C07D413/14 , A61K31/5377 , A61K31/4184
CPC classification number: C07D309/06 , A61K31/4178 , A61K31/4184 , A61K31/437 , A61K31/4375 , A61K31/4545 , A61K31/4709 , A61K31/498 , A61K31/4985 , A61K31/5377 , A61K45/06 , C07D401/14 , C07D403/10 , C07D403/14 , C07D405/14 , C07D413/14 , C07D471/04 , C07D487/04
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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