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1.发明公开公开(公告)号：US20240026081A1
公开(公告)日：2024-01-25
申请号：US18475397
申请日：2023-09-27
Applicant: Boston Scientific Scimed Inc.
Inventor： Joseph T. Delaney, JR. , Paul V. Grosso , John Kummailil , Tatyana Dyndikova , Carey Rehder
CPC classification number: C08G73/0233 , C08J3/24 , A61L27/52
Abstract: In some aspects, the present disclosure pertains to a multi-arm polymer comprising a core and a plurality of polyoxazoline segments (or arms) having a first end that is covalently attached to the core and a second end comprising a moiety that comprises a reactive group. In some aspects, systems are provided that comprise a first composition comprising such a multi-arm polymer and a second composition comprising a multifunctional compound that comprises functional groups that are reactive with the reactive groups of the multi-arm polymer. In some aspects, systems are provided that comprise crosslinked reaction products of such a multi-arm polymer and such a multifunctional compound.
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公开(公告)号：US20210061954A1
公开(公告)日：2021-03-04
申请号：US16999787
申请日：2020-08-21
Applicant: Boston Scientific Scimed Inc.
Inventor： Joseph T. Delaney, Jr. , Paul V. Grosso , John Kummailil , Tatyana Dyndikova , Carey Rehder
Abstract: In some aspects, the present disclosure pertains to a multi-arm polymer comprising a core and a plurality of polyoxazoline segments (or arms) having a first end that is covalently attached to the core and a second end comprising a moiety that comprises a reactive group. In some aspects, systems are provided that comprise a first composition comprising such a multi-arm polymer and a second composition comprising a multifunctional compound that comprises functional groups that are reactive with the reactive groups of the multi-arm polymer. In some aspects, systems are provided that comprise crosslinked reaction products of such a multi-arm polymer and such a multifunctional compound.
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Patent Agency Ranking
3.发明公开公开(公告)号：US20240117121A1
公开(公告)日：2024-04-11
申请号：US18489223
申请日：2023-10-18
Applicant: Boston Scientific Scimed Inc.
Inventor： Joseph T. Delaney, JR. , Paul V. Grosso , John Kummailil , Tatyana Dyndikova , Carey Rehder
IPC: C08G77/04 , C08F283/12
CPC classification number: C08G77/045 , C08F283/12 , A61L27/52
Abstract: In some aspects, the present disclosure pertains to multi-arm polymers that comprise a core and a plurality of polymer segments having a first end that is covalently attached to the core and (a) a second end comprising a moiety that comprises a reactive end group, wherein the polymer segments comprise one or more hydrophilic aprotic NMP-polymerizable monomers, and wherein the reactive multi-arm polymer comprises nitroxide radicals or (b) a second end comprising a moiety that comprises an alkoxyamine group, wherein the core is a polyol residue, and wherein the polymer segments comprise one or more NMP-polymerizable monomers. In some aspects, the present disclosure pertains to a multifunctional alkoxyamine molecule comprising a core and a plurality of alkoxyamine groups covalently attached to the core, wherein the core is a polyol residue.
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公开(公告)号：US12090509B2
公开(公告)日：2024-09-17
申请号：US18054188
申请日：2022-11-10
Applicant: Boston Scientific Scimed, Inc.
Inventor： Joseph T. Delaney, Jr. , John Kummailil , Paul V. Grosso , Yen-Hao Hsu
CPC classification number: B05D1/18 , B05D1/02 , B05D2202/00
Abstract: Methods of treating a substrate, e.g., forming a coating on the substrate, are described. The method may include applying a solution comprising a multifunctional molecule or a multifunctional-polymer molecule to at least a portion of a surface of the substrate. The surface may comprise a metal or metal alloy and the multifunctional molecule or a multifunctional-polymer molecule may bond to the surface via at least one sulfur group of a plurality of sulfur groups of the multifunctional molecule. The method may include combining the multifunctional molecule with a polymer molecule to form the multifunctional polymer molecule before or after applying the solution. The polymer molecule may bond to an internal carbon group or a terminal sulfur group of the multifunctional molecule.
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公开(公告)号：US11807720B2
公开(公告)日：2023-11-07
申请号：US16999787
申请日：2020-08-21
Applicant: Boston Scientific Scimed Inc.
Inventor： Joseph T. Delaney, Jr. , Paul V. Grosso , John Kummailil , Tatyana Dyndikova , Carey Rehder
CPC classification number: C08G73/0233 , C08J3/24 , A61L27/52
Abstract: In some aspects, the present disclosure pertains to a multi-arm polymer comprising a core and a plurality of polyoxazoline segments (or arms) having a first end that is covalently attached to the core and a second end comprising a moiety that comprises a reactive group. In some aspects, systems are provided that comprise a first composition comprising such a multi-arm polymer and a second composition comprising a multifunctional compound that comprises functional groups that are reactive with the reactive groups of the multi-arm polymer. In some aspects, systems are provided that comprise crosslinked reaction products of such a multi-arm polymer and such a multifunctional compound.
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公开(公告)号：US11820868B2
公开(公告)日：2023-11-21
申请号：US16999822
申请日：2020-08-21
Applicant: Boston Scientific Scimed Inc.
Inventor： Joseph T. Delaney, Jr. , Paul V. Grosso , John Kummailil , Tatyana Dyndikova , Carey Rehder
IPC: C08F283/12 , C08G77/04 , A61L27/52 , A61L27/58
CPC classification number: C08G77/045 , C08F283/12 , A61L27/52 , A61L27/58
Abstract: In some aspects, the present disclosure pertains to multi-arm polymers that comprise a core and a plurality of polymer segments having a first end that is covalently attached to the core and (a) a second end comprising a moiety that comprises a reactive end group, wherein the polymer segments comprise one or more hydrophilic aprotic NMP-polymerizable monomers, and wherein the reactive multi-arm polymer comprises nitroxide radicals or (b) a second end comprising a moiety that comprises an alkoxyamine group, wherein the core is a polyol residue, and wherein the polymer segments comprise one or more NMP-polymerizable monomers. In some aspects, the present disclosure pertains to a multifunctional alkoxyamine molecule comprising a core and a plurality of alkoxyamine groups covalently attached to the core, wherein the core is a polyol residue.
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公开(公告)号：US20210061957A1
公开(公告)日：2021-03-04
申请号：US16999822
申请日：2020-08-21
Applicant: Boston Scientific Scimed Inc.
Inventor： Joseph T. Delaney, JR. , Paul V. Grosso , John Kummailil , Tatyana Dyndikova , Carey Rehder
IPC: C08G77/04 , C08F283/12
Abstract: In some aspects, the present disclosure pertains to multi-arm polymers that comprise a core and a plurality of polymer segments having a first end that is covalently attached to the core and (a) a second end comprising a moiety that comprises a reactive end group, wherein the polymer segments comprise one or more hydrophilic aprotic NMP-polymerizable monomers, and wherein the reactive multi-arm polymer comprises nitroxide radicals or (b) a second end comprising a moiety that comprises an alkoxyamine group, wherein the core is a polyol residue, and wherein the polymer segments comprise one or more NMP-polymerizable monomers. In some aspects, the present disclosure pertains to a multifunctional alkoxyamine molecule comprising a core and a plurality of alkoxyamine groups covalently attached to the core, wherein the core is a polyol residue.
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