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公开(公告)号：US11559428B2
公开(公告)日：2023-01-24
申请号：US16510238
申请日：2019-07-12
Applicant: CLEARSIDE BIOMEDICAL, INC.
Inventor： Rafael Victor Andino , Vladimir Zarnitsyn , Jesse Yoo , Christopher John Brooks , Trent John Kahute , Justin William Arsenault , David Jackson Trettin , Andrew Kent Bauer , Stephanie Elaine Lewis
IPC: A61F9/00 , A61M5/20 , A61M5/48 , A61J1/20 , A61M5/46 , A61M37/00 , A61M5/31 , A61M5/34 , A61M5/32 , A61M5/315
Abstract: An apparatus includes a housing coupled to a medicament container, which is coupled to a needle. An injection assembly is disposed within the housing and includes an energy storage member and an actuation rod. A distal end portion of the actuation rod is disposed within the medicament container. The energy storage member can produce a force on a proximal end portion of the actuation rod sufficient to move the distal end portion of the actuation rod within the medicament container. This can convey at least a portion of a substance from the medicament container via the needle when a distal tip of the needle is disposed within a first region of a target location. The force is insufficient to move the distal end portion of the actuation rod within the medicament container when the distal tip of the needle is disposed within a second region of the target location.
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公开(公告)号：US10517756B2
公开(公告)日：2019-12-31
申请号：US16381213
申请日：2019-04-11
Applicant: CLEARSIDE BIOMEDICAL, INC.
Inventor： Rafael Victor Andino , Vladimir Zarnitsyn , Jesse Yoo , Christopher John Brooks , Trent John Kahute , Justin William Arsenault , David Jackson Trettin , Andrew Kent Bauer , Stephanie Elaine Lewis
IPC: A61F9/00 , A61M5/46 , A61M37/00 , A61M5/20 , A61M5/48 , A61J1/20 , A61M5/31 , A61M5/34 , A61M5/32 , A61M5/315
Abstract: An apparatus includes a housing coupled to a medicament container, which is coupled to a needle. An injection assembly is disposed within the housing and includes an energy storage member and an actuation rod. A distal end portion of the actuation rod is disposed within the medicament container. The energy storage member can produce a force on a proximal end portion of the actuation rod sufficient to move the distal end portion of the actuation rod within the medicament container. This can convey at least a portion of a substance from the medicament container via the needle when a distal tip of the needle is disposed within a first region of a target location. The force is insufficient to move the distal end portion of the actuation rod within the medicament container when the distal tip of the needle is disposed within a second region of the target location.
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公开(公告)号：US09180047B2
公开(公告)日：2015-11-10
申请号：US14523243
申请日：2014-10-24
Applicant: Clearside Biomedical, Inc.
Inventor： Rafael Victor Andino , Vladimir Zarnitsyn , Christopher John Brooks , Jesse Yoo
CPC classification number: A61F9/0017 , A61F2250/0007 , A61F2250/0069 , A61J1/201 , A61J1/2055 , A61J1/2096 , A61M5/2033 , A61M5/2053 , A61M5/31 , A61M5/3293 , A61M5/34 , A61M5/344 , A61M5/346 , A61M5/347 , A61M5/348 , A61M5/349 , A61M5/46 , A61M5/482 , A61M37/0015 , A61M2005/31508 , A61M2037/0023 , A61M2037/0061 , A61M2210/0612
Abstract: An apparatus includes a housing coupled to a medicament container, which is coupled to a needle. An injection assembly is disposed within the housing and includes an energy storage member and an actuation rod. A distal end portion of the actuation rod is disposed within the medicament container. The energy storage member can produce a force on a proximal end portion of the actuation rod sufficient to move the distal end portion of the actuation rod within the medicament container. This can convey at least a portion of a substance from the medicament container via the needle when a distal tip of the needle is disposed within a first region of a target location. The force is insufficient to move the distal end portion of the actuation rod within the medicament container when the distal tip of the needle is disposed within a second region of the target location.
Abstract translation: 一种装置包括联接到药物容器的壳体，其联接到针上。 注射组件设置在壳体内并且包括能量存储构件和致动杆。 致动杆的远端部分设置在药物容器内。 能量存储构件可以在致动杆的近端部分上产生足以将致动杆的远端部分移动到药物容器内的力。 当针的远端设置在目标位置的第一区域内时，这可以经由针从药物容器中传送至少一部分物质。 当针的远端设置在目标位置的第二区域内时，力不足以将致动杆的远端部分移动到药物容器内。
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公开(公告)号：US11596545B2
公开(公告)日：2023-03-07
申请号：US16178162
申请日：2018-11-01
Applicant: CLEARSIDE BIOMEDICAL, INC.
Inventor： Rafael Victor Andino , Thomas Edward Godfrey , Shelley Eckert Hancock , Samirkumar Patel , Keleigh Jo Mahn , Jesse Yoo , Vladimir Zarnitsyn
Abstract: Devices, methods, and kits for ocular drug delivery are described herein. An apparatus can include a housing, an energy storage member, a barrel, and a hub. The housing contains the energy storage member. A proximal end portion of the barrel is coupled to a distal end portion of the housing. The barrel is configured to contain medicament and includes at least a portion of a piston and an elastomeric member. The piston is configured to move the elastomeric member within the barrel in response to a force produced by the energy storage member. The hub is coupled to a distal end portion of the barrel. An inner surface of the hub defines a nozzle through which the medicament flows when the elastomeric member moves within the barrel. The nozzle and the energy storage member are collectively configured to produce a fluid jet to access a target location within an eye.
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公开(公告)号：US09770361B2
公开(公告)日：2017-09-26
申请号：US15472551
申请日：2017-03-29
Applicant: Clearside Biomedical, Inc.
Inventor： Rafael Victor Andino , Vladimir Zarnitsyn , Jesse Yoo , Christopher John Brooks , Trent John Kahute , Justin William Arsenault , David Jackson Trettin , Andrew Kent Bauer , Stephanie Elaine Lewis
IPC: A61M5/00 , A61F9/00 , A61J1/20 , A61M5/20 , A61M5/32 , A61M5/34 , A61M5/46 , A61M5/48 , A61M37/00
CPC classification number: A61F9/0017 , A61F2250/0007 , A61F2250/0069 , A61J1/201 , A61J1/2055 , A61J1/2096 , A61M5/2033 , A61M5/2053 , A61M5/31 , A61M5/3293 , A61M5/34 , A61M5/344 , A61M5/346 , A61M5/347 , A61M5/348 , A61M5/349 , A61M5/46 , A61M5/482 , A61M37/0015 , A61M2005/31508 , A61M2037/0023 , A61M2037/0061 , A61M2210/0612
Abstract: An apparatus includes a housing coupled to a medicament container, which is coupled to a needle. An injection assembly is disposed within the housing and includes an energy storage member and an actuation rod. A distal end portion of the actuation rod is disposed within the medicament container. The energy storage member can produce a force on a proximal end portion of the actuation rod sufficient to move the distal end portion of the actuation rod within the medicament container. This can convey at least a portion of a substance from the medicament container via the needle when a distal tip of the needle is disposed within a first region of a target location. The force is insufficient to move the distal end portion of the actuation rod within the medicament container when the distal tip of the needle is disposed within a second region of the target location.
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Patent Agency Ranking
公开(公告)号：US12201558B2
公开(公告)日：2025-01-21
申请号：US18156684
申请日：2023-01-19
Applicant: CLEARSIDE BIOMEDICAL, INC.
Inventor： Rafael Victor Andino , Vladimir Zarnitsyn , Jesse Yoo , Christopher John Brooks , Trent John Kahute , Justin William Arsenault , David Jackson Trettin , Andrew Kent Bauer , Stephanie Elaine Lewis
IPC: A61F9/00 , A61J1/20 , A61M5/20 , A61M5/31 , A61M5/32 , A61M5/34 , A61M5/46 , A61M5/48 , A61M37/00 , A61M5/315
Abstract: An apparatus includes a housing coupled to a medicament container, which is coupled to a needle. An injection assembly is disposed within the housing and includes an energy storage member and an actuation rod. A distal end portion of the actuation rod is disposed within the medicament container. The energy storage member can produce a force on a proximal end portion of the actuation rod sufficient to move the distal end portion of the actuation rod within the medicament container. This can convey at least a portion of a substance from the medicament container via the needle when a distal tip of the needle is disposed within a first region of a target location. The force is insufficient to move the distal end portion of the actuation rod within the medicament container when the distal tip of the needle is disposed within a second region of the target location.
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公开(公告)号：US10555833B2
公开(公告)日：2020-02-11
申请号：US15946838
申请日：2018-04-06
Applicant: CLEARSIDE BIOMEDICAL, INC.
Inventor： Rafael Victor Andino , Vladimir Zarnitsyn , Jesse Yoo , Christopher John Brooks , Trent John Kahute , Justin William Arsenault , David Jackson Trettin , Andrew Kent Bauer , Stephanie Elaine Lewis
IPC: A61F9/00 , A61M5/46 , A61M37/00 , A61M5/20 , A61M5/48 , A61J1/20 , A61M5/31 , A61M5/34 , A61M5/32 , A61M5/315
Abstract: An apparatus includes a housing coupled to a medicament container, which is coupled to a needle. An injection assembly is disposed within the housing and includes an energy storage member and an actuation rod. A distal end portion of the actuation rod is disposed within the medicament container. The energy storage member can produce a force on a proximal end portion of the actuation rod sufficient to move the distal end portion of the actuation rod within the medicament container. This can convey at least a portion of a substance from the medicament container via the needle when a distal tip of the needle is disposed within a first region of a target location. The force is insufficient to move the distal end portion of the actuation rod within the medicament container when the distal tip of the needle is disposed within a second region of the target location.
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公开(公告)号：US09636253B1
公开(公告)日：2017-05-02
申请号：US15399239
申请日：2017-01-05
Applicant: Clearside Biomedical, Inc.
Inventor： Rafael Victor Andino , Vladimir Zarnitsyn , Jesse Yoo , Christopher John Brooks , Trent John Kahute , Justin William Arsenault , David Jackson Trettin , Andrew Kent Bauer , Stephanie Elaine Lewis
CPC classification number: A61F9/0017 , A61F2250/0007 , A61F2250/0069 , A61J1/201 , A61J1/2055 , A61J1/2096 , A61M5/2033 , A61M5/2053 , A61M5/31 , A61M5/3293 , A61M5/34 , A61M5/344 , A61M5/346 , A61M5/347 , A61M5/348 , A61M5/349 , A61M5/46 , A61M5/482 , A61M37/0015 , A61M2005/31508 , A61M2037/0023 , A61M2037/0061 , A61M2210/0612
Abstract: An apparatus includes a housing coupled to a medicament container, which is coupled to a needle. An injection assembly is disposed within the housing and includes an energy storage member and an actuation rod. A distal end portion of the actuation rod is disposed within the medicament container. The energy storage member can produce a force on a proximal end portion of the actuation rod sufficient to move the distal end portion of the actuation rod within the medicament container. This can convey at least a portion of a substance from the medicament container via the needle when a distal tip of the needle is disposed within a first region of a target location. The force is insufficient to move the distal end portion of the actuation rod within the medicament container when the distal tip of the needle is disposed within a second region of the target location.
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公开(公告)号：US20230157869A1
公开(公告)日：2023-05-25
申请号：US18156684
申请日：2023-01-19
Applicant: CLEARSIDE BIOMEDICAL, INC.
Inventor： Rafael Victor ANDINO , Vladimir Zarnitsyn , Jesse Yoo , Christopher John Brooks , Trent John Kahute , Justin William Arsenault , David Jackson Trettin , Andrew Kent Bauer , Stephanie Elaine Lewis
IPC: A61F9/00 , A61M5/20 , A61M5/48 , A61J1/20 , A61M5/46 , A61M37/00 , A61M5/31 , A61M5/34 , A61M5/32
CPC classification number: A61F9/0017 , A61M5/2033 , A61M5/2053 , A61M5/482 , A61J1/2096 , A61J1/201 , A61J1/2055 , A61M5/46 , A61M37/0015 , A61M5/31 , A61M5/34 , A61M5/3293 , A61M5/344 , A61M5/346 , A61M5/347 , A61M5/348 , A61M5/349 , A61M2005/31508
Abstract: An apparatus includes a housing coupled to a medicament container, which is coupled to a needle. An injection assembly is disposed within the housing and includes an energy storage member and an actuation rod. A distal end portion of the actuation rod is disposed within the medicament container. The energy storage member can produce a force on a proximal end portion of the actuation rod sufficient to move the distal end portion of the actuation rod within the medicament container. This can convey at least a portion of a substance from the medicament container via the needle when a distal tip of the needle is disposed within a first region of a target location. The force is insufficient to move the distal end portion of the actuation rod within the medicament container when the distal tip of the needle is disposed within a second region of the target location.
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公开(公告)号：US10722396B2
公开(公告)日：2020-07-28
申请号：US16591067
申请日：2019-10-02
Applicant: CLEARSIDE BIOMEDICAL, INC.
Inventor： Rafael Victor Andino , Vladimir Zarnitsyn , Jesse Yoo , Christopher John Brooks , Trent John Kahute , Justin William Arsenault , David Jackson Trettin , Andrew Kent Bauer , Stephanie Elaine Lewis
IPC: A61F9/00 , A61M5/20 , A61M5/48 , A61J1/20 , A61M5/46 , A61M37/00 , A61M5/31 , A61M5/34 , A61M5/32 , A61M5/315
Abstract: An apparatus includes a housing coupled to a medicament container, which is coupled to a needle. An injection assembly is disposed within the housing and includes an energy storage member and an actuation rod. A distal end portion of the actuation rod is disposed within the medicament container. The energy storage member can produce a force on a proximal end portion of the actuation rod sufficient to move the distal end portion of the actuation rod within the medicament container. This can convey at least a portion of a substance from the medicament container via the needle when a distal tip of the needle is disposed within a first region of a target location. The force is insufficient to move the distal end portion of the actuation rod within the medicament container when the distal tip of the needle is disposed within a second region of the target location.
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