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公开(公告)号:US20190269586A1
公开(公告)日:2019-09-05
申请号:US16414847
申请日:2019-05-17
Applicant: Colgate-Palmolive Company
Inventor: Michael PRENCIPE , Yun XU , Xiao Yi HUANG , Steven FISHER , Betty WON , Lyndsay SCHAEFFER-KORBYLO
Abstract: Described herein are oral care compositions comprising a combination of zinc oxide and zinc citrate, and methods of preparing and using the same.
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公开(公告)号:US20180263885A1
公开(公告)日:2018-09-20
申请号:US15749537
申请日:2017-06-23
Applicant: Colgate-Palmolive Company
Inventor: Marcella MOURAO , Wilbens JOSIAS , Betty WON , Lisa MANUS , Michael STRANICK , Xiaoyi HUANG , Michael PRENCIPE , Amy RUSSO , Hansruedi STETTLER , Peng YAN , Chengkang TAN , Vyoma PATEL , Andre Michelle MORGAN , Andrei POTANIN
Abstract: Described herein are oral care compositions comprising a basic amino acid; a combination of zinc ion sources; and from about 0.75 wt. % to about 2 wt. % of a chelating system; along with methods of making and using same.
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公开(公告)号:US20210401705A1
公开(公告)日:2021-12-30
申请号:US17359026
申请日:2021-06-25
Applicant: Colgate-Palmolive Company
Inventor: Ningwei LI , Hongwei SHEN , Saide TANG , Betty WON , Viktor DUBOVOY , Long PAN
Abstract: This application provides, among other things, novel aqueous oral care compositions useful for combining and delivering poorly compatible ingredients, in particular, chlorhexidine and polyphosphate salts, by formulating the composition with a surfactant.
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公开(公告)号:US20170247740A1
公开(公告)日:2017-08-31
申请号:US15509901
申请日:2014-09-24
Applicant: Colgate-Palmolive Company
Inventor: Lyndsay SCHAEFFER-KORBYLO , Betty WON , Venda Porter MALONEY , Gregory SZEWCZYK
IPC: C12Q1/18
Abstract: Provided herein is a method for determining the bioavailability of a metal ion in a composition comprising a source of the metal ion, wherein the metal ion has antimicrobial activity, and wherein the method comprises: a) incubating a sample of the composition with bacterial cells, and b) determining the viability of the bacterial cells after incubation. The method is useful for determining the effect of agents on the bioavailability of metal ions in a composition.
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公开(公告)号:US20220387279A1
公开(公告)日:2022-12-08
申请号:US17825365
申请日:2022-05-26
Applicant: Colgate-Palmolive Company
Inventor: Murilo Nogueira NAKAJIMA , Saide TANG , Betty WON , Enzo UTIMA , Guofeng XU , Paloma PIMENTA , Sarita Vera MELLO , Melissa MUIR
Abstract: This application provides, among other things, oral care compositions where the addition of a stabilizing amount of a nonionic gelling and thickening agent, (e.g., hydroxyethyl cellulose (HEC)), to formulations comprising a bisbiguanide (e.g., chlorhexidine (CHX)) agent allows for proper structure and consistency to the formulation and to allow it to be used as a gel or a toothpaste to facility delivery of chlorhexidine, among other actives, to the teeth or gums.
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公开(公告)号:US20220125698A1
公开(公告)日:2022-04-28
申请号:US17571179
申请日:2022-01-07
Applicant: Colgate-Palmolive Company
Inventor: Michael PRENCIPE , Amy RUSSO , Hansruedi STETTLER , Betty WON , Lisa Marie MANUS , Michael STRANICK , Peng YAN , Chengkang TAN , Vyoma PATEL , André MORGAN , Andrei POTANIN , Xiao Yi HUANG
IPC: A61K8/44 , A61K8/24 , A61K8/27 , A61Q11/00 , A61K8/73 , A61K8/21 , A61K8/04 , A61K8/37 , A61K8/25 , A61K8/34 , A61K8/365
Abstract: This invention relates to oral care compositions comprising arginine or lysine, zinc citrate and zinc oxide, fluoride source, and a silica abrasive which exhibits an acid pH when measured as an aqueous slurry as well as to methods of using and of making these compositions.
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公开(公告)号:US20200206116A1
公开(公告)日:2020-07-02
申请号:US16815106
申请日:2020-03-11
Applicant: Colgate-Palmolive Company
Inventor: Michael PRENCIPE , Amy RUSSO , Hansruedi STETTLER , Betty WON , Lisa MANUS , Michael STRANICK , Peng YAN , Chengkang TAN , Vyoma PATEL , André MORGAN , Andrei POTANIN , Xiao Yi HUANG
IPC: A61K8/44 , A61K8/365 , A61K8/34 , A61K8/25 , A61K8/37 , A61K8/04 , A61K8/21 , A61K8/73 , A61Q11/00 , A61K8/27 , A61K8/24
Abstract: This invention relates to oral care compositions comprising arginine or lysine, zinc citrate and zinc oxide, fluoride source, and a silica abrasive which exhibits an acid pH when measured as an aqueous slurry as well as to methods of using and of making these compositions.
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公开(公告)号:US20240415746A1
公开(公告)日:2024-12-19
申请号:US18744029
申请日:2024-06-14
Applicant: Colgate-Palmolive Company
Inventor: Joshua Eric KAUFFMAN , Qichao RUAN , Nihal DOGU , Stacey LAVENDER , Betty WON , Michael STRANICK , Shiyou XU , Luciana RINAUDI MARRON , Dennis ZHANG
Abstract: Oral care compositions and, e.g., to oral care compositions adapted to form a film on an enamel substrate are disclosed herein. In accordance with an aspect, provided is a method having from about 1 to about 10 wt. % of a fluoride ion source; optionally, from about 2 to about 20 wt. % of hydroxyapatite; from about 3 to about 30 wt. % of a film-forming agent; and from about 7 to about 35 wt. % of an adhesive, wherein the oral care composition is adapted to form a film on teeth, and all weight percentages are based on the total weight of the oral care composition.
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公开(公告)号:US20240197600A1
公开(公告)日:2024-06-20
申请号:US18531033
申请日:2023-12-06
Applicant: Colgate-Palmolive Company
Inventor: Nihal DOGU , Betty WON , Paloma PIMENTA , Lyndsay SCHAEFFER-KORBYLO , Joseph Allan McKinnon STEELE , Lisa Marie MANUS , Lauren EVANS , Michael NORTH
CPC classification number: A61K8/466 , A61Q11/00 , A61K2800/52 , A61K2800/592 , A61K2800/92
Abstract: This application relates to novel anti-bacterial mouthwash compositions comprising hyaluronic acid, cetyl pyridinium chloride, and taurate surfactant, having unexpected stability, and their use in treating plaque, gingivitis, bad breath, implant infections, tooth decay, inflammation, and dental staining, as well as helping to moisturize and protect the teeth and gums.
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公开(公告)号:US20240024233A1
公开(公告)日:2024-01-25
申请号:US18251428
申请日:2021-11-03
Applicant: Colgate-Palmolive Company
Inventor: Lisa MANUS , Joseph STEELE , Guillaume PICQUET , Christine PADULA , Dandan CHEN , Betty WON , Andrei POTANIN
Abstract: The present invention relates to oral hydrogel compositions, more particularly to thermosensitive gel compositions, which undergo a sol-gel transition in the oral cavity, and which optionally comprise therapeutic actives for sustained release.
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