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    Disposable device for diagnostic assays
    1.
    发明授权
    Disposable device for diagnostic assays 失效
    一次性诊断测定装置

    公开(公告)号：US5503985A

    公开(公告)日：1996-04-02

    申请号：US179749

    申请日：1994-01-07

    申请人： Cheryl A. Cathey ,  Henry L. Schwartz ,  Tom Saul ,  Jeffrey D. Langford

    发明人： Cheryl A. Cathey ,  Henry L. Schwartz ,  Tom Saul ,  Jeffrey D. Langford

    IPC分类号： G01N33/48 ,  B01F13/00 ,  B01F13/08 ,  B01L3/00 ,  C12M1/34 ,  C12Q1/00 ,  G01N33/52 ,  G01N33/543 ,  G01N35/00 ,  G01N33/542 ,  G01N33/558

    CPC分类号： B01L3/50273 ,  B01F13/0059 ,  B01F13/0818 ,  B01L3/5027 ,  B01L3/502746 ,  G01N33/54366 ,  B01L2200/10 ,  B01L2200/16 ,  B01L2300/0816 ,  B01L2300/087 ,  B01L2400/0406 ,  B01L2400/0688 ,  B01L2400/086 ,  B01L3/502738 ,  G01N2035/00267 ,  Y10S435/81 ,  Y10S435/973 ,  Y10S436/805 ,  Y10S436/807 ,  Y10S436/808 ,  Y10S436/81

    摘要： A disposable diagnostic device and method of its use are provided. The device comprises a housing containing first and second flow paths orthogonal to each other. The first flow path commences at a sample addition port and continues through a transport channel which feeds sample to an incubation area by means of capillary flow. The incubation area comprises a signal producing system and is underneath an optically-clear window. The first flow path terminates in a top waste reservoir which receives sample and wash fluid. The second flow path begins on one side of the incubation area at an inlet port over a side reagent reservoir. Liquid flows along the second flow path from the side reagent reservoir across the incubation area into the side waste reservoir. The incubation area may comprise agitation means for homogenous dispersion of reagent into liquid. Various reagents of a signal producing system may be contained within the device and the necessary liquids added automatically by appropriate instrumentation, so as to have the assay carried out automatically, without technician involvement, providing an accurate and sensitive determination.

    摘要翻译： 提供了一次性诊断装置及其使用方法。 该装置包括容纳彼此正交的第一和第二流动路径的壳体。 第一流路在样品加入口处开始并继续通过运送通道，其通过毛细管流将样品送入孵育区。 孵化区包括信号产生系统，并在光学透明的窗口下方。 第一流路终止于接收样品和洗涤流体的顶部废物储存器中。 第二流路在侧试剂储存器的入口处从孵化区的一侧开始。 液体沿着第二流动路径从侧面试剂储存器流过孵化区域流入侧面废物储存器。 孵育区域可以包括用于将试剂均匀分散到液体中的搅拌装置。 信号产生系统的各种试剂可以包含在装置内，并且通过适当的仪器自动加入必需的液体，以便在没有技术人员参与的情况下自动进行测定，提供精确和灵敏的测定。

    Disposable device in diagnostic assays
    2.
    发明授权
    Disposable device in diagnostic assays 失效
    诊断测定中的一次性装置

    公开(公告)号：US5698406A

    公开(公告)日：1997-12-16

    申请号：US414331

    申请日：1995-03-30

    申请人： Cheryl A. Cathey ,  Henry L. Schwartz ,  Tom Saul ,  Jeffrey D. Langford

    发明人： Cheryl A. Cathey ,  Henry L. Schwartz ,  Tom Saul ,  Jeffrey D. Langford

    IPC分类号： G01N33/48 ,  B01F13/00 ,  B01F13/08 ,  B01L3/00 ,  C12M1/34 ,  C12Q1/00 ,  G01N33/52 ,  G01N33/543 ,  G01N35/00 ,  G01N33/53 ,  G01N33/558

    CPC分类号： B01L3/50273 ,  B01F13/0059 ,  B01F13/0818 ,  B01L3/5027 ,  B01L3/502746 ,  G01N33/54366 ,  B01L2200/10 ,  B01L2200/16 ,  B01L2300/0816 ,  B01L2300/087 ,  B01L2400/0406 ,  B01L2400/0688 ,  B01L2400/086 ,  B01L3/502738 ,  G01N2035/00267 ,  Y10S435/81 ,  Y10S435/973 ,  Y10S436/805 ,  Y10S436/807 ,  Y10S436/808 ,  Y10S436/81

    摘要： A disposable diagnostic device and method of its use are provided. The device comprises a housing containing first and second flow paths orthogonal to each other. The first flow path commences at a sample addition port and continues through a transport channel which feeds sample to an incubation area by means of capillary flow. The incubation area comprises a signal producing system and is underneath an optically-clear window. The first flow path terminates in a top waste reservoir which receives sample and wash fluid. The second flow path begins on one side of the incubation area at an inlet port over a side reagent reservoir. Liquid flows along the second flow path from the side reagent reservoir across the incubation area into the side waste reservoir. The incubation area may comprise agitation means for homogenous dispersion of reagent into liquid. Various reagents of a signal producing system may be contained within the device and the necessary liquids added automatically by appropriate instrumentation, so as to have the assay carried out automatically, without technician involvement, providing an accurate and sensitive determination.

    摘要翻译： 提供了一次性诊断装置及其使用方法。 该装置包括容纳彼此正交的第一和第二流动路径的壳体。 第一流路在样品加入口处开始并继续通过运送通道，其通过毛细管流将样品送入孵育区。 孵化区包括信号产生系统，并在光学透明的窗口下方。 第一流路终止于接收样品和洗涤流体的顶部废物储存器中。 第二流路在侧试剂储存器的入口处从孵化区的一侧开始。 液体沿着第二流动路径从侧面试剂储存器流过孵化区域流入侧面废物储存器。 孵育区域可以包括用于将试剂均匀分散到液体中的搅拌装置。 信号产生系统的各种试剂可以包含在装置内，并且通过适当的仪器自动加入必需的液体，以便在没有技术人员参与的情况下自动进行测定，提供精确和灵敏的测定。

    Clearing silicate kogation
    5.
    发明授权
    Clearing silicate kogation 有权
    清除硅酸盐结垢

    公开(公告)号：US07543908B2

    公开(公告)日：2009-06-09

    申请号：US11209574

    申请日：2005-08-23

    申请人： Morgan G. Jones ,  Satya Prakash ,  Jeffrey D. Langford

    发明人： Morgan G. Jones ,  Satya Prakash ,  Jeffrey D. Langford

    IPC分类号： B41J2/165 ,  B41J2/05

    CPC分类号： B41J2/14112

    摘要： Systems, methodologies, media, and other embodiments associated with clearing silicate based kogation from heating resistors employed in ink jet printing are described. One exemplary system embodiment includes a silicate kogation clearing logic configured to pulse the heating resistor at a high frequency and low pulse width to heat the resistor surface to a temperature below that required to form an ink bubble and thus below that required to eject a drop of ink. Heating the resistor facilitates breaking bonds between the silicate based kogation and the heating resistor.

    摘要翻译： 描述了与喷墨印刷中使用的加热电阻器清除基于硅酸盐的结垢有关的系统，方法，介质和其它实施方案。 一个示例性的系统实施例包括硅酸盐转移清除逻辑，其被配置为以高频率和低脉冲宽度脉冲加热电阻器，以将电阻器表面加热到低于形成墨水泡所需的温度，因此低于喷射一滴 墨水。 加热电阻器有助于破坏硅酸盐基烧结和加热电阻之间的接合。