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公开(公告)号:US07910331B2
公开(公告)日:2011-03-22
申请号:US12616476
申请日:2009-11-11
CPC分类号: C07K14/52 , A61K38/00 , C07K14/54 , G01N33/6869
摘要: CTLA-8 related antigens from mammals, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding said antigens. Methods of using said reagents and diagnostic kits are also provided.
摘要翻译: 来自哺乳动物的CTLA-8相关抗原,与其相关的试剂,包括纯化的蛋白质,特异性抗体和编码所述抗原的核酸。 还提供了使用所述试剂和诊断试剂盒的方法。
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公开(公告)号:US07645445B2
公开(公告)日:2010-01-12
申请号:US11952779
申请日:2007-12-07
IPC分类号: A61K38/20
CPC分类号: C07K14/52 , A61K38/00 , C07K14/54 , G01N33/6869
摘要: CTLA-8 related antigens from mammals, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding said antigens. Methods of using said reagents and diagnostic kits are also provided.
摘要翻译: 来自哺乳动物的CTLA-8相关抗原,与其相关的试剂,包括纯化的蛋白质,特异性抗体和编码所述抗原的核酸。 还提供了使用所述试剂和诊断试剂盒的方法。
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公开(公告)号:US20100210012A1
公开(公告)日:2010-08-19
申请号:US12616476
申请日:2009-11-11
CPC分类号: C07K14/52 , A61K38/00 , C07K14/54 , G01N33/6869
摘要: CTLA-8 related antigens from mammals, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding said antigens. Methods of using said reagents and diagnostic kits are also provided.
摘要翻译: 来自哺乳动物的CTLA-8相关抗原,与其相关的试剂,包括纯化的蛋白质,特异性抗体和编码所述抗原的核酸。 还提供了使用所述试剂和诊断试剂盒的方法。
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公开(公告)号:US07655761B2
公开(公告)日:2010-02-02
申请号:US11952802
申请日:2007-12-07
IPC分类号: C07K16/00
CPC分类号: C07K14/52 , A61K38/00 , C07K14/54 , G01N33/6869
摘要: CTLA-8 related antigens from mammals, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding said antigens. Methods of using said reagents and diagnostic kits are also provided.
摘要翻译: 来自哺乳动物的CTLA-8相关抗原,与其相关的试剂,包括纯化的蛋白质,特异性抗体和编码所述抗原的核酸。 还提供了使用所述试剂和诊断试剂盒的方法。
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公开(公告)号:US07625720B2
公开(公告)日:2009-12-01
申请号:US11604559
申请日:2006-11-27
CPC分类号: C07K14/52 , A61K38/00 , C07K14/54 , G01N33/6869
摘要: CTLA-8 related antigens from mammals, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding said antigens. Methods of using said reagents and diagnostic kits are also provided.
摘要翻译: 来自哺乳动物的CTLA-8相关抗原,与其相关的试剂,包括纯化的蛋白质,特异性抗体和编码所述抗原的核酸。 还提供了使用所述试剂和诊断试剂盒的方法。
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公开(公告)号:US07005501B2
公开(公告)日:2006-02-28
申请号:US10366791
申请日:2003-02-14
CPC分类号: C07K14/52 , A61K38/00 , C07K14/54 , G01N33/6869
摘要: CTLA-8 related antigens from mammals, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding said antigens. Methods of using said reagents and diagnostic kits are also provided.
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公开(公告)号:US06562578B1
公开(公告)日:2003-05-13
申请号:US09480297
申请日:2000-01-10
IPC分类号: G01N3353
CPC分类号: C07K14/52 , A61K38/00 , C07K14/54 , G01N33/6869
摘要: IL-17-like cytokines from mammals, reagents and diagnostic kits related thereto including purified proteins, specific antibodies, and nucleic acids are provided. Methods of using the reagents and diagnostic kits are also provided.
摘要翻译: 提供了来自哺乳动物的IL-17样细胞因子,与其相关的试剂和诊断试剂盒,包括纯化的蛋白质,特异性抗体和核酸。 还提供了使用试剂和诊断试剂盒的方法。
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公开(公告)号:US08691953B2
公开(公告)日:2014-04-08
申请号:US13330902
申请日:2011-12-20
申请人: Jacqueline C. Timans , Stefan Karl-Heinz Pflanz , Robert A. Kastelein , J. Fernando Bazan , Donna Rennick , Rene de Waal Malefyt , Jeanne Cheung
发明人: Jacqueline C. Timans , Stefan Karl-Heinz Pflanz , Robert A. Kastelein , J. Fernando Bazan , Donna Rennick , Rene de Waal Malefyt , Jeanne Cheung
IPC分类号: C07K16/00
CPC分类号: C07K14/54 , C07K14/5434 , C07K16/244 , C12Q1/6881 , Y10S436/808
摘要: Purified genes encoding a cytokine or composite cytokine from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding these molecules are provided. Methods of using said reagents and diagnostic kits are also provided.
摘要翻译: 提供了编码来自哺乳动物的细胞因子或复合细胞因子的纯化基因,与其相关的试剂,包括纯化蛋白质,特异性抗体和编码这些分子的核酸。 还提供了使用所述试剂和诊断试剂盒的方法。
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公开(公告)号:US20090041718A1
公开(公告)日:2009-02-12
申请号:US12239689
申请日:2008-09-26
IPC分类号: A61K38/20 , A61K48/00 , A61K31/711 , A61K39/395 , G01N33/68
CPC分类号: G01N33/6869 , A61K38/00 , A61K38/20 , A61K2039/505 , C07K16/244 , C07K16/2866 , C07K2317/76 , Y02A50/41 , Y02A50/423
摘要: Provided are methods of modulating cytokine activity, e.g., for the purpose of treating immune and inflammatory disorders, including tumors and cancer. Also provided are methods of administering agonists or antagonists of IL-33 and IL-33 receptor.
摘要翻译: 提供了调节细胞因子活性的方法,例如用于治疗免疫和炎性疾病(包括肿瘤和癌症)的目的。 还提供施用IL-33和IL-33受体的激动剂或拮抗剂的方法。
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公开(公告)号:US20120115164A1
公开(公告)日:2012-05-10
申请号:US13330902
申请日:2011-12-20
申请人: Jacqueline C. Timans , Stefan Karl-Heinz Pflanz , Robert A. Kastelein , J. Fernando Bazan , Donna Rennick , Rene de Waal Malefyt , Jeanne Cheung
发明人: Jacqueline C. Timans , Stefan Karl-Heinz Pflanz , Robert A. Kastelein , J. Fernando Bazan , Donna Rennick , Rene de Waal Malefyt , Jeanne Cheung
CPC分类号: C07K14/54 , C07K14/5434 , C07K16/244 , C12Q1/6881 , Y10S436/808
摘要: Purified genes encoding a cytokine or composite cytokine from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding these molecules are provided. Methods of using said reagents and diagnostic kits are also provided.
摘要翻译: 提供了编码来自哺乳动物的细胞因子或复合细胞因子的纯化基因,与其相关的试剂,包括纯化蛋白质,特异性抗体和编码这些分子的核酸。 还提供了使用所述试剂和诊断试剂盒的方法。
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