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    Expandable sheath for introducing an endovascular delivery device into a body
    1.
    发明授权
    Expandable sheath for introducing an endovascular delivery device into a body 有权
    用于将血管内输送装置引入体内的可扩展护套

    公开(公告)号：US08790387B2

    公开(公告)日：2014-07-29

    申请号：US13312739

    申请日：2011-12-06

    申请人： Duy Nguyen ,  Kim Nguyen ,  Thanh V. Nguyen

    发明人： Duy Nguyen ,  Kim Nguyen ,  Thanh V. Nguyen

    IPC分类号： A61F2/06 ,  A61F2/24 ,  A61B19/00

    CPC分类号： A61F2/2427 ,  A61B90/39 ,  A61F2/2418 ,  A61F2/2433 ,  A61F2/2436 ,  Y10T156/1026

    摘要： Embodiments of an expandable sheath can be used in conjunction with a catheter assembly to introduce a prosthetic device, such as a heart valve, into a patient. Such embodiments can minimize trauma to the vessel by allowing for temporary expansion of a portion of the introducer sheath to accommodate the delivery apparatus, followed by a return to the original diameter once the prosthetic device passes through. Some embodiments can include a sheath with inner and outer layers, where a folded portion of the inner layer extends through a slit in the outer layer and a portion of the outer layer overlaps the folded portion of the inner layer. Some embodiments include an elastic outer cover positioned outside the outer layer. Embodiments of the present expandable sheath can avoid the need for multiple insertions for the dilation of the vessel, thus offering advantages over prior art introducer sheaths.

    摘要翻译： 可扩张护套的实施例可以与导管组件一起使用以将诸如心脏瓣膜的假体装置引入患者体内。 这样的实施例可以通过允许引导器护套的一部分临时膨胀以适应输送装置来最小化对容器的创伤，然后一旦假肢装置通过就恢复到原始直径。 一些实施例可以包括具有内层和外层的护套，其中内层的折叠部分延伸穿过外层中的狭缝，并且外层的一部分与内层的折叠部分重叠。 一些实施例包括位于外层外部的弹性外盖。 本发明的可扩张护套的实施例可以避免需要多次插入用于扩张容器，从而提供优于现有技术的导引器护套的优点。

    Expandable sheath for introducing an endovascular delivery device into a body
    2.
    发明授权
    Expandable sheath for introducing an endovascular delivery device into a body 有权
    用于将血管内输送装置引入体内的可扩展护套

    公开(公告)号：US08690936B2

    公开(公告)日：2014-04-08

    申请号：US12249867

    申请日：2008-10-10

    申请人： Duy Nguyen ,  Kim Nguyen

    发明人： Duy Nguyen ,  Kim Nguyen

    IPC分类号： A61F2/06

    CPC分类号： A61F2/2436 ,  A61B90/39 ,  A61F2/2418 ,  A61F2/2427 ,  A61M25/0023 ,  A61M25/0045 ,  A61M25/0668 ,  A61M2025/0024 ,  A61M2025/0681

    摘要： Embodiments of an expandable sheath can be used in conjunction with a catheter assembly to introduce a prosthetic device, such as a tissue heart valve, into a patient. Such embodiments can minimize trauma to the vessel by allowing for temporary expansion of a portion of the introducer sheath to accommodate the delivery apparatus, followed by a return to the original diameter once the prosthetic device passes through. Some embodiments can comprise a sheath with inner and outer tubular layers, and an intermediate tubular layer comprising a shape memory alloy. Other embodiments comprise one or more layers having one or more longitudinal notches or cuts to facilitate expansion of the sheath. Embodiments of the present expandable sheath can avoid the need for multiple insertions for the dilation of the vessel, thus offering advantages over prior art introducer sheaths.

    摘要翻译： 可扩张护套的实施例可以与导管组件一起使用以将假体装置（例如组织心脏瓣膜）引入患者体内。 这样的实施例可以通过允许引导器护套的一部分临时膨胀以适应输送装置来最小化对容器的创伤，然后一旦假肢装置通过就恢复到原始直径。 一些实施例可以包括具有内部和外部管状层的护套以及包括形状记忆合金的中间管状层。 其它实施例包括具有一个或多个纵向凹口或切口以便于护套膨胀的一个或多个层。 本发明的可扩张护套的实施例可以避免需要多次插入用于扩张容器，从而提供优于现有技术的导引器护套的优点。

    Expandable Sheath for Introducing an Endovascular Delivery Device into a Body
    3.
    发明申请
    Expandable Sheath for Introducing an Endovascular Delivery Device into a Body 有权
    可扩展护套用于将血管内输送装置引入体内

    公开(公告)号：US20100094392A1

    公开(公告)日：2010-04-15

    申请号：US12249867

    申请日：2008-10-10

    申请人： Duy Nguyen ,  Kim Nguyen

    发明人： Duy Nguyen ,  Kim Nguyen

    IPC分类号： A61F2/06 ,  A61B19/00

    CPC分类号： A61F2/2436 ,  A61B90/39 ,  A61F2/2418 ,  A61F2/2427 ,  A61M25/0023 ,  A61M25/0045 ,  A61M25/0668 ,  A61M2025/0024 ,  A61M2025/0681

    摘要： Embodiments of an expandable sheath can be used in conjunction with a catheter assembly to introduce a prosthetic device, such as a tissue heart valve, into a patient. Such embodiments can minimize trauma to the vessel by allowing for temporary expansion of a portion of the introducer sheath to accommodate the delivery apparatus, followed by a return to the original diameter once the prosthetic device passes through. Some embodiments can comprise a sheath with inner and outer tubular layers, and an intermediate tubular layer comprising a shape memory alloy. Other embodiments comprise one or more layers having one or more longitudinal notches or cuts to facilitate expansion of the sheath. Embodiments of the present expandable sheath can avoid the need for multiple insertions for the dilation of the vessel, thus offering advantages over prior art introducer sheaths.

    摘要翻译： 可扩张护套的实施例可以与导管组件一起使用以将假体装置（例如组织心脏瓣膜）引入患者体内。 这样的实施例可以通过允许引导器护套的一部分临时膨胀以适应输送装置来最小化对容器的创伤，然后一旦假肢装置通过就恢复到原始直径。 一些实施例可以包括具有内部和外部管状层的护套以及包括形状记忆合金的中间管状层。 其它实施例包括具有一个或多个纵向凹口或切口以便于护套膨胀的一个或多个层。 本发明的可扩张护套的实施例可以避免需要多次插入用于扩张容器，从而提供优于现有技术的导引器护套的优点。

    Retrievable implant and method for treatment of mitral regurgitation
    4.
    发明申请
    Retrievable implant and method for treatment of mitral regurgitation 审中-公开
    可回收的植入物和治疗二尖瓣反流的方法

    公开(公告)号：US20080065205A1

    公开(公告)日：2008-03-13

    申请号：US11519519

    申请日：2006-09-11

    申请人： Duy Nguyen ,  Kim Nguyen

    发明人： Duy Nguyen ,  Kim Nguyen

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2451 ,  A61F2/2466 ,  A61F2/885 ,  A61F2250/0098

    摘要： The invention is a device, and method for deploying same, configured for placement in a body lumen such as a coronary sinus, as may be desired to repair a mitral valve. The device includes a first anchor, a second anchor, and a bridge. The anchors are configured to delivered to a desired deployment site within the body lumen in a collapsed or contracted condition, and then be deployed by expanding the anchors into contact with the walls of the body lumen. One or more of the anchors may be configured to be radially collapsible after initial deployment in order to permit the anchor(s) to be repositioned in or removed from the body lumen. An anchor may be collapsible in response to a distal force applied to a portion of a proximal end thereof. A catheter for use with the implant is configured to deliver the implant to the site with the anchors in their respective collapsed configurations, and to release the anchors to permit them to expand into contact with the walls of the body lumen. The catheter is configured to apply a proximal force to one or both anchors, which may be applied via a cinch wire. The catheter may also be configured to apply a distal force against a portion of the proximal end of one or more of the anchors.

    摘要翻译： 本发明是一种用于部署其的装置及其方法，其被配置用于放置在诸如冠状窦的体腔中，可能需要修复二尖瓣。 该装置包括第一锚，第二锚和桥。 锚固件构造成在塌陷或收缩状态下输送到体腔内的期望的部署部位，然后通过将锚定件与体腔的壁接触来展开。 锚定器中的一个或多个可以被配置为在初始展开之后可径向收缩，以便允许锚定体重新定位在身体内腔中或从体腔移除。 响应于施加到其近端的一部分的远端力，锚可以可折叠。 与植入物一起使用的导管被配置成将植入物递送到具有各自的折叠构造的锚固件的位置，并且释放锚固件以允许它们膨胀成与体腔的壁接触。 导管构造成将近端力施加到一个或两个锚固件，其可以经由束缚线施加。 导管还可以被配置为向一个或多个锚固件的近端的一部分施加远端力。

    EXPANDABLE SHEATH FOR INTRODUCING AN ENDOVASCULAR DELIVERY DEVICE INTO A BODY
    5.
    发明申请
    EXPANDABLE SHEATH FOR INTRODUCING AN ENDOVASCULAR DELIVERY DEVICE INTO A BODY 有权
    将内膜输送装置引入身体的可扩展的护理

    公开(公告)号：US20120083877A1

    公开(公告)日：2012-04-05

    申请号：US13312739

    申请日：2011-12-06

    申请人： Duy Nguyen ,  Kim Nguyen ,  Thanh V. Nguyen

    发明人： Duy Nguyen ,  Kim Nguyen ,  Thanh V. Nguyen

    IPC分类号： A61F2/24 ,  B29C53/08

    CPC分类号： A61F2/2427 ,  A61B90/39 ,  A61F2/2418 ,  A61F2/2433 ,  A61F2/2436 ,  Y10T156/1026

    摘要： Embodiments of an expandable sheath can be used in conjunction with a catheter assembly to introduce a prosthetic device, such as a heart valve, into a patient. Such embodiments can minimize trauma to the vessel by allowing for temporary expansion of a portion of the introducer sheath to accommodate the delivery apparatus, followed by a return to the original diameter once the prosthetic device passes through. Some embodiments can include a sheath with inner and outer layers, where a folded portion of the inner layer extends through a slit in the outer layer and a portion of the outer layer overlaps the folded portion of the inner layer. Some embodiments include an elastic outer cover positioned outside the outer layer. Embodiments of the present expandable sheath can avoid the need for multiple insertions for the dilation of the vessel, thus offering advantages over prior art introducer sheaths.

    摘要翻译： 可扩张护套的实施例可以与导管组件一起使用以将诸如心脏瓣膜的假体装置引入患者体内。 这样的实施例可以通过允许引导器护套的一部分临时膨胀以适应输送装置来最小化对容器的创伤，然后一旦假肢装置通过就恢复到原始直径。 一些实施例可以包括具有内层和外层的护套，其中内层的折叠部分延伸穿过外层中的狭缝，并且外层的一部分与内层的折叠部分重叠。 一些实施例包括位于外层外部的弹性外盖。 本发明的可扩张护套的实施例可以避免需要多次插入用于扩张容器，从而提供优于现有技术的导引器护套的优点。

    CAMPAIGN OPTIMIZATION SYSTEM
    6.
    发明申请
    CAMPAIGN OPTIMIZATION SYSTEM 审中-公开
    航空优化系统

    公开(公告)号：US20160371725A1

    公开(公告)日：2016-12-22

    申请号：US15186421

    申请日：2016-06-17

    申请人： Duy Nguyen ,  Vu Huy Tran

    发明人： Duy Nguyen ,  Vu Huy Tran

    IPC分类号： G06Q30/02 ,  G06F17/30

    CPC分类号： G06Q30/0246 ,  G06F16/9535 ,  G06F16/957

    摘要： A method and apparatuses can include: crawling web sites including an advertiser web site and a publisher website; identifying a resource article from the websites, the resource article including a title, an image, and body content; generating a resource article topic model; identifying a current article being read by a user; generating a current article topic model for the current article; calculating a semantic score by measuring the similarity between the resource article topic model and the current article topic model; calculating a reader score based on a click history of the user and a browsing history of the user; calculating a traffic score based on a demographic relationship between the current article and the resource article; and recommending the resource article to the user based on the semantic score, the reader score, and the traffic score indicating the user will select the resource article.

    摘要翻译： 方法和装置可以包括：爬行网站，包括广告商网站和发布者网站; 从网站识别资源文章，资源文章包括标题，图像和正文内容; 生成资源文章主题模型; 识别由用户读取的当前文章; 生成当前文章的当前文章主题模型; 通过测量资源文章主题模型与当前文章主题模型的相似性来计算语义分数; 基于用户的点击历史和用户的浏览历史来计算阅读器分数; 根据当前文章和资源文章之间的人口统计关系计算交通分数; 并且基于语义分数，读者得分以及指示用户将选择资源文章的交通分数向用户推荐资源文章。

    Deflectable variable radius catheters
    9.
    发明授权
    Deflectable variable radius catheters 有权
    可变半径导管

    公开(公告)号：US08182467B2

    公开(公告)日：2012-05-22

    申请号：US12569786

    申请日：2009-09-29

    申请人： Duy Nguyen ,  Sheldon Nelson ,  Elizabeth Nee ,  Guy P. Vanney

    发明人： Duy Nguyen ,  Sheldon Nelson ,  Elizabeth Nee ,  Guy P. Vanney

    IPC分类号： A61B5/04 ,  A61B18/18 ,  A61M25/00 ,  A61M31/00 ,  A61M37/00

    CPC分类号： A61M25/0152 ,  A61M25/0043 ,  A61M25/0136 ,  A61M25/0141 ,  A61M25/0147 ,  A61M2025/015 ,  A61M2025/0161 ,  A61M2025/105

    摘要： The invention provides a deflectable catheter capable of forming many variable radius spiral forms from a single, flexible, distal end section. In one aspect, the catheter employs a variable radius control wire to extend or deform a pre-formed loop structure into a three dimensional spiral-like form or geometry. The ability of a single catheter to create a multitude of shapes and sizes allows users to access to a number of anatomical areas without changing the catheter during a procedure or treatment. In another aspect, the invention encompasses methods of producing deflectable variable radius catheters, where two or more regions of the catheter having common control wires are fused or formed onto one another.

    摘要翻译： 本发明提供了一种能够从单个柔性远端部分形成许多可变半径螺旋形状的可偏转导管。 在一个方面，导管使用可变半径控制线来将预成形的环结构延伸或变形为三维螺旋形的形状或几何形状。 单个导管创建多种形状和尺寸的能力允许用户在手术或治疗期间不改变导管的情况下进入多个解剖区域。 在另一方面，本发明包括生产可偏转可变半径导管的方法，其中具有公共控制线的导管的两个或更多个区域彼此熔合或形成。