公开(公告)号：USD1074358S1

公开(公告)日：2025-05-13

申请号：US29871647

申请日：2023-02-24

Applicant: EMD Millipore Corporation

Designer： Michael Miller ,  Kurt E. Greenizen ,  Ryan Amara ,  Christopher A. Scott ,  Paul Sydlowski ,  Kelly Wolfe

公开(公告)号：US20240309195A1

公开(公告)日：2024-09-19

申请号：US18578419

申请日：2022-08-22

Applicant: EMD Millipore Corporation

Inventor： Kevin Wu ,  Kelly Wolfe ,  Anja Dedeo ,  Ryan Amara ,  Gerard Libby ,  Paul Sydlowski ,  Katelyn Kavanaugh ,  Trisha Bailey ,  Nathan T. Allen

IPC: C08L33/26 ,  C08J9/28 ,  G01N27/447

CPC classification number: C08L33/26 ,  C08J9/28 ,  G01N27/44747 ,  C08J2333/26

Abstract: An acrylamide gel formulation for use in electrophoresis, and a system and method for electrophoretic gel casting. In some embodiments, the system comprises a UV-Vis curing light source, and an acrylamide formulation that allows a resolving gel and a stacking gel to be photopolymerized in a single step. In some embodiments, the resolving solution formulation comprises acrylamide and bis-acrylamide, Bis-Tris buffering agent, and lithium phenyl-2, 4, 6-trimethylbenzoyl-phosphinate (LAP) as a water-soluble photoinitiator, which allows the solution to be photopolymerized using UV radiation within a certain wavelength. In some embodiments, a dilution buffer formulation comprises acrylamide and bis-acrylamide, Bis-Tris buffering agent, and lithium phenyl-2, 4, 6-trimethyl-benzoyl-phosphinate (LAP). The dilution buffer may be added to the resolving solution in a selected amount in order to modify the concentration of the acrylamide to a desired concentration.

公开(公告)号：US20240192166A1

公开(公告)日：2024-06-13

申请号：US18533928

申请日：2023-12-08

Applicant: EMD Millipore Corporation

Inventor： Kurt E. Greenizen ,  Ryan Amara ,  Christopher A. Scott ,  Paul Sydlowski ,  Michael Miller ,  Kelly Wolfe

IPC: G01N27/447

CPC classification number: G01N27/44743

Abstract: A removal tool for sample well combs that is configured to aid in the extraction of a sample well comb from an electrophoresis gel. The removal tool may be either removably coupled to the sample well comb or may be permanently affixed to the sample well comb in order to provide a surface/region that is more easily graspable by a user to aid in the extraction of the sample well comb. The removal tool may include one or more engagement members that may be at least partially disposed within an opening of the sample well comb to couple the removal tool to the sample well comb. The removal tool may also include a mechanism that is configured to impart extraction forces to a surface in proximity to the sample well comb to further aid in the extraction of the sample well comb.

公开(公告)号：US20150260621A1

公开(公告)日：2015-09-17

申请号：US14618007

申请日：2015-02-10

Applicant: EMD Millipore Corporation

Inventor： Chris Scott ,  Paul Sydlowski ,  John Doyle ,  Ryan Amara ,  Libby Kellard ,  Sara Gutierrez ,  Marc Emerick

IPC: G01N1/31

Abstract: Apparatus and method for Immunohistochemistry, including a slide holder assembly fixture, a slide holder, a slide holder frame, and a slide holder frame assembly adapted to be placed in communication with a driving force to draw fluid through the slide holder. The slide holder may include an injection port that allows consistent fluid delivery and recovery, while minimizing the introduction of air bubbles. The slide holder may include a reservoir that allows for filling, soaking, rinsing, flushing, uniform antibody coverage of the tissue and reduces handling time, space, and errors, and one or more sample chambers. The slide orientation in the slide holder allows for visualization of label information and tissue to confirm adequate antibody coverage. A multi-port frame allows multiple assays to be carried out concurrently, and is removable from a vacuum manifold and allows for easy transport from the vacuum manifold to an incubator/refrigerator and back.

Abstract translation: 用于免疫组织化学的装置和方法，包括滑动支架组件夹具，滑动支架，滑动支架框架和滑动支架框架组件，其适于与驱动力连通以将流体通过滑块保持器拉动。 滑动架可以包括一个注射口，其允许一致的流体输送和回收，同时最小化气泡的引入。 载玻片保持器可以包括允许填充，浸泡，漂洗，冲洗，组织的均匀抗体覆盖并减少处理时间，空间和错误以及一个或多个样品室的储存器。 幻灯片固定器中的滑动方向允许标记信息和组织的可视化，以确认足够的抗体覆盖。 多端口框架允许多个测定同时进行，并且可从真空歧管移除，并且允许从真空歧管到培养箱/冰箱和背部的容易运输。