公开(公告)号：US12226266B2

公开(公告)日：2025-02-18

申请号：US18138600

申请日：2023-04-24

Applicant: ENDOMAGNETICS LTD

Inventor： Tiziano Agostinelli ,  Kevin Lorimer ,  Quentin John Harmer

IPC: A61B90/00 ,  A61B5/06 ,  A61B34/20 ,  G01D5/20 ,  A61B17/00

Abstract: A detection system and method uses an implantable magnetic marker comprising at least one piece of a large Barkhausen jump material (LBJ). The marker is deployed to mark a tissue site in the body for subsequent surgery, and the magnetic detection system includes a handheld probe to excite the marker below the switching field for bistable switching of the marker causing a harmonic response to be generated in a sub-bistable mode that allows the marker to be detected and localised. The marker implanted may also be shorter than the critical length required to initiate bistable switching of the LBJ material.

公开(公告)号：US12207915B2

公开(公告)日：2025-01-28

申请号：US18024448

申请日：2021-09-06

Applicant: ENDOMAGNETICS LTD

Inventor： Quentin John Harmer ,  Tiziano Agostinelli

IPC: A61B5/06 ,  A61B6/12 ,  A61B34/20 ,  A61B90/00

Abstract: Systems and Methods for Detecting Magnetic Markers for Surgical Guidance Methods and systems for detecting a magnetic marker for guiding a surgeon to a region of interest during a surgical procedure comprising generating a driving magnetic field having a cyclic pattern comprising two or more successive periods of time, the driving magnetic field having a substantially constant, non-zero amplitude during each of the successive periods of time, and the amplitude of the driving magnetic field during at least one of the periods of time being different from the amplitude of the driving magnetic field during at least one other of the periods of time; detecting a response magnetic field; selecting at least one signal from a plurality of sensed signals, each of which corresponds to the response magnetic field detected during a respective one of the successive periods of time of each cycle; determining a detection signal corresponding to the magnetic marker using the at least one selected signal; and generating an output signal (e.g. an audio or display signal) based on a strength of the detection signal.

公开(公告)号：US20230329834A1

公开(公告)日：2023-10-19

申请号：US18138600

申请日：2023-04-24

Applicant: ENDOMAGNETICS LTD

Inventor： Tiziano Agostinelli ,  Kevin Lorimer ,  Quentin John Harmer

IPC: A61B90/00 ,  A61B5/06 ,  A61B34/20 ,  G01D5/20

CPC classification number: A61B90/39 ,  A61B5/064 ,  A61B34/20 ,  A61B5/062 ,  G01D5/20 ,  A61B2090/3908 ,  A61B2505/05 ,  A61B2034/2051 ,  A61B2090/3966 ,  A61B2017/00867

Abstract: A detection system and method uses an implantable magnetic marker comprising at least one piece of a large Barkhausen jump material (LBJ). The marker is deployed to mark a tissue site in the body for subsequent surgery, and the magnetic detection system includes a handheld probe to excite the marker below the switching field for bistable switching of the marker causing a harmonic response to be generated in a sub-bistable mode that allows the marker to be detected and localised. The marker implanted may also be shorter than the critical length required to initiate bistable switching of the LBJ material.

公开(公告)号：US20230346251A1

公开(公告)日：2023-11-02

申请号：US18131126

申请日：2023-04-05

Applicant: Endomagnetics Ltd

Inventor： Quentin John Harmer ,  Tiziano Agostinelli

IPC: A61B5/06 ,  A61B5/00

CPC classification number: A61B5/062 ,  A61B5/7221 ,  A61B5/725 ,  A61B5/7405 ,  A61B5/7435 ,  A61B5/7475 ,  A61B2090/3954

Abstract: In part, the disclosure relates to a method of detecting a marker in a subject in the presence of one or more interfering signals. The method may include detecting a first marker signal; detecting a first interfering signal; comparing one or more characteristics or a metric correlated therewith of the first interfering signal with an interference signal threshold; and generating user feedback based on the comparison and/or movement of a detection probe.

公开(公告)号：US20230277083A1

公开(公告)日：2023-09-07

申请号：US18024448

申请日：2021-09-06

Applicant: ENDOMAGNETICS LTD

Inventor： Quentin John Harmer ,  Tiziano Agostinelli

IPC: A61B5/06 ,  A61B90/00

CPC classification number: A61B5/062 ,  A61B90/39 ,  A61B2090/3954

Abstract: Systems and Methods for Detecting Magnetic Markers for Surgical Guidance Methods and systems for detecting a magnetic marker for guiding a surgeon to a region of interest during a surgical procedure comprising generating a driving magnetic field having a cyclic pattern comprising two or more successive periods of time, the driving magnetic field having a substantially constant, non-zero amplitude during each of the successive periods of time, and the amplitude of the driving magnetic field during at least one of the periods of time being different from the amplitude of the driving magnetic field during at least one other of the periods of time; detecting a response magnetic field; selecting at least one signal from a plurality of sensed signals, each of which corresponds to the response magnetic field detected during a respective one of the successive periods of time of each cycle; determining a detection signal corresponding to the magnetic marker using the at least one selected signal; and generating an output signal (e.g. an audio or display signal) based on a strength of the detection signal.

公开(公告)号：US11660160B2

公开(公告)日：2023-05-30

申请号：US16256404

申请日：2019-01-24

Applicant: ENDOMAGNETICS LTD

Inventor： Tiziano Agostinelli ,  Kevin Lorimer ,  Quentin John Harmer

IPC: A61B5/00 ,  A61B90/00 ,  A61B5/06 ,  A61B34/20 ,  G01D5/20 ,  A61B17/00

CPC classification number: A61B90/39 ,  A61B5/062 ,  A61B5/064 ,  A61B34/20 ,  G01D5/20 ,  A61B2017/00867 ,  A61B2017/00876 ,  A61B2034/2051 ,  A61B2090/397 ,  A61B2090/3908 ,  A61B2090/3925 ,  A61B2090/3954 ,  A61B2090/3958 ,  A61B2090/3966 ,  A61B2090/3987 ,  A61B2505/05 ,  A61B2562/0223

Abstract: A detection system and method uses an implantable magnetic marker comprising at least one piece of a large Barkhausen jump material (LBJ). The marker is deployed to mark a tissue site in the body for subsequent surgery, and the magnetic detection system includes a handheld probe to excite the marker below the switching field for bistable switching of the marker causing a harmonic response to be generated in a sub-bistable mode that allows the marker to be detected and localised. The marker implanted may also be shorter than the critical length required to initiate bistable switching of the LBJ material.

公开(公告)号：US20190223975A1

公开(公告)日：2019-07-25

申请号：US16256404

申请日：2019-01-24

Applicant: ENDOMAGNETICS LTD

Inventor： Tiziano Agostinelli ,  Kevin Lorimer ,  Quentin John Harmer

IPC: A61B90/00 ,  A61B5/06 ,  G01D5/20

Abstract: A detection system and method uses an implantable magnetic marker comprising at least one piece of a large Barkhausen jump material (LBJ). The marker is deployed to mark a tissue site in the body for subsequent surgery, and the magnetic detection system includes a handheld probe to excite the marker below the switching field for bistable switching of the marker causing a harmonic response to be generated in a sub-bistable mode that allows the marker to be detected and localised. The marker implanted may also be shorter than the critical length required to initiate bistable switching of the LBJ material.