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公开(公告)号：US09316331B2
公开(公告)日：2016-04-19
申请号：US14091342
申请日：2013-11-27
Applicant: Fluidigm Corporation
Inventor： Geoffrey Facer , Brian Fowler , Emerson Cheung Quan , Marc Unger
IPC: B01L3/00 , G05D11/02 , F16K99/00 , B01F5/02 , B01F13/00 , C12Q1/68 , G01N21/75 , F16K3/00 , G01N21/03
CPC classification number: F16K99/0015 , B01F5/02 , B01F13/0059 , B01L3/502707 , B01L3/502738 , B01L2200/10 , B01L2200/12 , B01L2200/16 , B01L2300/0627 , B01L2300/0816 , B01L2300/0874 , B01L2300/0887 , B01L2300/123 , B01L2400/0481 , B01L2400/0638 , B33Y80/00 , C12Q1/686 , F16K99/0026 , F16K99/0059 , F16K2099/008 , F16K2099/0084 , G01N2021/0346 , Y10T137/0329 , Y10T137/2164 , Y10T137/2169 , Y10T137/2559 , Y10T137/2655 , Y10T137/2688 , Y10T137/87249
Abstract: Multilevel microfluidic devices include a control line that can simultaneously actuate valves for both sample and reagent lines. Microfluidic devices are configured to contain a first reagent in a first chamber and a second reagent in a second chamber, where either or both of the first and second reagents are contained at a desired or selected pressure. Operation of a microfluidic device includes transmitting second reagent from the second chamber to the first chamber, for mixing or contact with the first reagent. Microfluidic device features such as channels, valves, chambers, can be at least partially contained, embedded, or formed by or within one or more layers or levels of an elastomeric block.
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公开(公告)号：US08616227B1
公开(公告)日：2013-12-31
申请号：US13909000
申请日：2013-06-03
Applicant: Fluidigm Corporation
Inventor： Geoffrey Facer , Brian Fowler , Emerson Cheung Quan , Marc Unger
CPC classification number: F16K99/0015 , B01F5/02 , B01F13/0059 , B01L3/502707 , B01L3/502738 , B01L2200/10 , B01L2200/12 , B01L2200/16 , B01L2300/0627 , B01L2300/0816 , B01L2300/0874 , B01L2300/0887 , B01L2300/123 , B01L2400/0481 , B01L2400/0638 , B33Y80/00 , C12Q1/686 , F16K99/0026 , F16K99/0059 , F16K2099/008 , F16K2099/0084 , G01N2021/0346 , Y10T137/0329 , Y10T137/2164 , Y10T137/2169 , Y10T137/2559 , Y10T137/2655 , Y10T137/2688 , Y10T137/87249
Abstract: Multilevel microfluidic devices include a control line that can simultaneously actuate valves for both sample and reagent lines. Microfluidic devices are configured to contain a first reagent in a first chamber and a second reagent in a second chamber, where either or both of the first and second reagents are contained at a desired or selected pressure. Operation of a microfluidic device includes transmitting second reagent from the second chamber to the first chamber, for mixing or contact with the first reagent. Microfluidic device features such as channels, valves, chambers, can be at least partially contained, embedded, or formed by or within one or more layers or levels of an elastomeric block.
Abstract translation: 多级微流体装置包括一个控制管线，可同时为样品和试剂管线起动阀门。 微流体装置被配置为在第二室中的第一室和第二试剂中含有第一试剂，其中第一试剂和第二试剂中的任一种或两者以所需或选择的压力包含。 微流体装置的操作包括将第二试剂从第二室传输到第一室，用于与第一试剂混合或接触。 诸如通道，阀，腔室的微流体装置特征可以至少部分地包含，嵌入或由弹性体块的一个或多个层或层形成或形成。
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公开(公告)号：US20130337457A1
公开(公告)日：2013-12-19
申请号：US13909000
申请日：2013-06-03
Applicant: Fluidigm Corporation
Inventor： Geoffrey Facer , Brian Fowler , Emerson Cheung Quan , Marc Unger
IPC: C12Q1/68
CPC classification number: F16K99/0015 , B01F5/02 , B01F13/0059 , B01L3/502707 , B01L3/502738 , B01L2200/10 , B01L2200/12 , B01L2200/16 , B01L2300/0627 , B01L2300/0816 , B01L2300/0874 , B01L2300/0887 , B01L2300/123 , B01L2400/0481 , B01L2400/0638 , B33Y80/00 , C12Q1/686 , F16K99/0026 , F16K99/0059 , F16K2099/008 , F16K2099/0084 , G01N2021/0346 , Y10T137/0329 , Y10T137/2164 , Y10T137/2169 , Y10T137/2559 , Y10T137/2655 , Y10T137/2688 , Y10T137/87249
Abstract: Multilevel microfluidic devices include a control line that can simultaneously actuate valves for both sample and reagent lines. Microfluidic devices are configured to contain a first reagent in a first chamber and a second reagent in a second chamber, where either or both of the first and second reagents are contained at a desired or selected pressure. Operation of a microfluidic device includes transmitting second reagent from the second chamber to the first chamber, for mixing or contact with the first reagent. Microfluidic device features such as channels, valves, chambers, can be at least partially contained, embedded, or formed by or within one or more layers or levels of an elastomeric block.
Abstract translation: 多级微流体装置包括一个控制管线，可同时为样品和试剂管线起动阀门。 微流体装置被配置为在第二室中的第一室和第二试剂中含有第一试剂，其中第一试剂和第二试剂中的任一种或两者以所需或选择的压力包含。 微流体装置的操作包括将第二试剂从第二室传输到第一室，用于与第一试剂混合或接触。 诸如通道，阀，腔室的微流体装置特征可以至少部分地包含，嵌入或由弹性体块的一个或多个层或层形成或形成。
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公开(公告)号：US20140318633A1
公开(公告)日：2014-10-30
申请号：US14091342
申请日：2013-11-27
Applicant: Fluidigm Corporation
Inventor： Geoffrey Facer , Brian Fowler , Emerson Cheung Quan , Marc Unger
IPC: F16K99/00
CPC classification number: F16K99/0015 , B01F5/02 , B01F13/0059 , B01L3/502707 , B01L3/502738 , B01L2200/10 , B01L2200/12 , B01L2200/16 , B01L2300/0627 , B01L2300/0816 , B01L2300/0874 , B01L2300/0887 , B01L2300/123 , B01L2400/0481 , B01L2400/0638 , B33Y80/00 , C12Q1/686 , F16K99/0026 , F16K99/0059 , F16K2099/008 , F16K2099/0084 , G01N2021/0346 , Y10T137/0329 , Y10T137/2164 , Y10T137/2169 , Y10T137/2559 , Y10T137/2655 , Y10T137/2688 , Y10T137/87249
Abstract: Multilevel microfluidic devices include a control line that can simultaneously actuate valves for both sample and reagent lines. Microfluidic devices are configured to contain a first reagent in a first chamber and a second reagent in a second chamber, where either or both of the first and second reagents are contained at a desired or selected pressure. Operation of a microfluidic device includes transmitting second reagent from the second chamber to the first chamber, for mixing or contact with the first reagent. Microfluidic device features such as channels, valves, chambers, can be at least partially contained, embedded, or formed by or within one or more layers or levels of an elastomeric block.
Abstract translation: 多级微流体装置包括一个控制管线，可同时为样品和试剂管线起动阀门。 微流体装置被配置为在第二室中的第一室和第二试剂中含有第一试剂，其中第一试剂和第二试剂中的任一种或两者以所需或选择的压力包含。 微流体装置的操作包括将第二试剂从第二室传输到第一室，用于与第一试剂混合或接触。 诸如通道，阀，腔室的微流体装置特征可以至少部分地包含，嵌入或由弹性体块的一个或多个层或层形成或形成。
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