利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

5 条记录 (耗时 0.023 秒)

    Method of cell isolation
    1.
    发明授权
    Method of cell isolation 失效
    细胞分离方法

    公开(公告)号：US08741635B2

    公开(公告)日：2014-06-03

    申请号：US11596397

    申请日：2005-05-12

    申请人： Geoffrey John Lindeman ,  Mark Shackleton ,  Francois Vaillant ,  Jane Ellen Visvader

    发明人： Geoffrey John Lindeman ,  Mark Shackleton ,  Francois Vaillant ,  Jane Ellen Visvader

    IPC分类号： C12N5/00

    CPC分类号： G01N33/5073 ,  C12N5/0631 ,  C12N2501/01 ,  C12N2501/11 ,  C12N2501/33 ,  C12N2501/39

    摘要： The present invention relates generally to a method for the generation of a substantially homogenous population of undifferentiated cells. More particularly, the present invention relates to a method for isolating a substantially homogenous population of stem cells, and in particular, mammary stem cells (MaSCs). The MaSCs of the present invention are isolated on the basis of differential levels of proteins present on their cell surface. The MaSCs of the present invention are particularly useful as targets for identifying agents which modulate MaSC survival, self-renewal, proliferation and/or differentiation in both normal and diseased tissue such as, but not limited to, tumor tissue, and, also as source of tissue for the regeneration, replacement and/or augmentation of tissue damaged and/or lost after disease or injury.

    摘要翻译： 本发明一般涉及产生基本均匀的未分化细胞群的方法。 更具体地说，本发明涉及用于分离基本均匀的干细胞群，特别是乳腺干细胞（MaSCs）的方法。 基于存在于其细胞表面上的蛋白质的差异水平分离本发明的MaSC。 本发明的MaSCs特别可用作鉴定调节正常组织和患病组织中MaSC存活，自我更新，增殖和/或分化的药剂的靶标，所述组织例如但不限于肿瘤组织，以及作为来源 的组织用于在疾病或损伤后损伤和/或丢失的组织的再生，置换和/或增加。

    Method Of Cell Isolation
    2.
    发明申请
    Method Of Cell Isolation 失效
    细胞分离方法

    公开(公告)号：US20080038230A1

    公开(公告)日：2008-02-14

    申请号：US11596397

    申请日：2005-05-12

    申请人： Geoffrey Lindeman ,  Mark Shackleton ,  Francois Vaillant ,  Jane Visvader

    发明人： Geoffrey Lindeman ,  Mark Shackleton ,  Francois Vaillant ,  Jane Visvader

    IPC分类号： C12N5/08 ,  A61K35/55 ,  A61K45/00 ,  C12Q1/02 ,  C12N5/00

    CPC分类号： G01N33/5073 ,  C12N5/0631 ,  C12N2501/01 ,  C12N2501/11 ,  C12N2501/33 ,  C12N2501/39

    摘要： The present invention relates generally to a method for the generation of a substantially homogenous population of undifferentiated cells. More particularly, the present invention relates to a method for isolating a substantially homogenous population of stem cells, and in particular, mammary stem cells (MaSCs). The MaSCs of the present invention are isolated on the basis of differential levels of proteins present on their cell surface. The MaSCs of the present invention are particularly useful as targets for identifying agents which modulate MaSC survival, self-renewal, proliferation and/or differentiation in both normal and diseased tissue such as, but not limited to, tumor tissue, and, also as source of tissue for the regeneration, replacement and/or augmentation of tissue damaged and/or lost after disease or injury.

    摘要翻译： 本发明一般涉及产生基本均匀的未分化细胞群的方法。 更具体地说，本发明涉及用于分离基本均匀的干细胞群，特别是乳腺干细胞（MaSCs）的方法。 基于存在于其细胞表面上的蛋白质的差异水平分离本发明的MaSC。 本发明的MaSCs特别可用作鉴定调节正常组织和患病组织中MaSC存活，自我更新，增殖和/或分化的药剂的靶标，所述组织例如但不限于肿瘤组织，以及作为来源 的组织用于在疾病或损伤后损伤和/或丢失的组织的再生，置换和/或增加。

    Multiprocessor system for intercommunication of processors
    5.
    发明授权
    Multiprocessor system for intercommunication of processors 失效
    处理器互通的多处理器系统

    公开(公告)号：US4719562A

    公开(公告)日：1988-01-12

    申请号：US631986

    申请日：1984-07-18

    申请人： Francois P. Bailly ,  Alain Bourgoin ,  Francois Vaillant

    发明人： Francois P. Bailly ,  Alain Bourgoin ,  Francois Vaillant

    IPC分类号： G06F15/167 ,  G06F13/00 ,  G06F15/16

    CPC分类号： G06F15/167

    摘要： The system according to the invention comprises a central microprocessor and peripheral microprocessors. A direct-access transfer memory is provided for the communication of the processors with one another. The memory is divided into as many distinct, determined zones as there are peripheral processors. The memory is connected to two addressing buses of which the latter serves equally well to address the boxes of the memory by the central microprocessor and to address the zones of the memory allocated to the peripheral microprocessors. The system is particularly well adapted to data transfers between a telephone automatic switch and subscribers' sets.

    摘要翻译： 根据本发明的系统包括中央微处理器和外围微处理器。 提供了一种用于处理器彼此通信的直接访问转移存储器。 存储器被分成与外围处理器一样多的不同的，确定的区域。 存储器连接到两个寻址总线，其后者同样适用于中央微处理器对存储器的盒进行寻址，并且对分配给外围微处理器的存储器的区域进行寻址。 该系统特别适用于电话自动切换和用户组之间的数据传输。