Liquid to Liquid Biological Particle Concentrator with Disposable Fluid Path

    公开(公告)号:US20210208032A1

    公开(公告)日:2021-07-08

    申请号:US17209434

    申请日:2021-03-23

    Applicant: InnovaPrep LLC

    Abstract: Highly efficient and rapid filtration-based concentration devices, systems and methods are disclosed with sample fluidic lines and a filter packaged in a disposable tip which concentrate biological particles that are suspended in liquid from a dilute feed suspension. A sample concentrate or retentate suspension is retained while eliminating the separated fluid in a separate flow stream. The concentrate is then dispensed from the disposable tip in a set volume of elution fluid. Suspended biological particles include such materials as proteins/toxins, viruses, DNA, and/or bacteria in the size range of approximately 0.001 micron to 20 microns diameter. Concentration of these particles is advantageous for detection of target particles in a dilute suspension, because concentrating them into a small volume makes them easier to detect. A single-use pipette tip includes fluid ports for aspirating the sample and connecting to a concentrating unit.

    Liquid to liquid biological particle concentrator with disposable fluid path

    公开(公告)号:US10955316B2

    公开(公告)日:2021-03-23

    申请号:US15431655

    申请日:2017-02-13

    Applicant: InnovaPrep LLC

    Abstract: Highly efficient and rapid filtration-based concentration devices, systems and methods are disclosed with sample fluidic lines and a filter packaged in a disposable tip which concentrate biological particles that are suspended in liquid from a dilute feed suspension. A sample concentrate or retentate suspension is retained while eliminating the separated fluid in a separate flow stream. The concentrate is then dispensed from the disposable tip in a set volume of elution fluid. Suspended biological particles include such materials as proteins/toxins, viruses, DNA, and/or bacteria in the size range of approximately 0.001 micron to 20 microns diameter. Concentration of these particles is advantageous for detection of target particles in a dilute suspension, because concentrating them into a small volume makes them easier to detect. A single-use pipette tip includes fluid ports for aspirating the sample and connecting to a concentrating unit.

    Liquid to Liquid Biological Particle Concentrator with Disposable Fluid Path

    公开(公告)号:US20170184478A1

    公开(公告)日:2017-06-29

    申请号:US15456981

    申请日:2017-03-13

    Applicant: InnovaPrep LLC

    Abstract: Highly efficient and rapid filtration-based concentration devices, systems and methods are disclosed with sample fluidic lines and a filter packaged in a disposable tip which concentrate biological particles that are suspended in liquid from a dilute feed suspension. A sample concentrate or retentate suspension is retained while eliminating the separated fluid in a separate flow stream. The concentrate is then dispensed from the disposable tip in a set volume of elution fluid. Suspended biological particles include such materials as proteins/toxins, viruses, DNA, and/or bacteria in the size range of approximately 0.001 micron to 20 microns diameter. Concentration of these particles is advantageous for detection of target particles in a dilute suspension, because concentrating them into a small volume makes them easier to detect. All conduits by which the disposable tip attaches to the instrument are combined into a single connection point on the upper end of the tip.

    Devices, systems and methods for elution of particles from flat filters
    8.
    发明授权
    Devices, systems and methods for elution of particles from flat filters 有权
    用于从平面过滤器中洗脱颗粒的装置,系统和方法

    公开(公告)号:US09534989B2

    公开(公告)日:2017-01-03

    申请号:US14084403

    申请日:2013-11-19

    Applicant: InnovaPrep LLC

    Abstract: Devices, systems and methods are disclosed which relate to using a wet foam elution method for removal of particles from a flat filter. Particles are captured from the atmosphere onto the flat filter. The flat filter is then placed into an extractor which passes a stream of wet foam through the flat filter. Expansion of the foam works to efficiently remove captured particles. The foam flows from the filter along with the captured particles into a sample container. Once in the sample container, the foam quickly breaks down leaving an analysis ready liquid sample.

    Abstract translation: 公开了涉及使用湿泡沫洗脱法从扁平过滤器去除颗粒的装置,系统和方法。 颗粒从大气中捕获到扁平过滤器上。 然后将扁平过滤器放入提取器中,该提取器将湿泡沫流通过扁平过滤器。 泡沫的膨胀用于有效去除捕获的颗粒。 泡沫从捕获的颗粒与过滤器一起流入样品容器。 一旦在样品容器中,泡沫快速分解,留下分析就绪的液体样品。

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