专利检索 ap:("Jing Wu" OR "Jay Tung" OR "Eugene Thorsett" OR "Michael Pleiss" OR "Jeffrey Nissen" OR "Jeffrey Neitz" OR "Lee Latimer" OR "Varghese John" OR "Stephen Freedman" OR "Thomas Britton" OR "James Audia" OR "Jon Reel" OR "Thomas Mabry" OR "Bruce Dressman" OR "Cynthia Cwi" OR "James Droste" OR "Steven Henry" OR "Stacey McDaniel" OR "William Scott" OR "Russell Stucky" OR "Warren Porter") AND inv:"Jeffrey Neitz" 第 1 页

1.

发明申请
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds 审中-公开

公开(公告)号：US20050272666A1

公开(公告)日：2005-12-08

申请号：US11001610

申请日：2004-12-02

申请人： Jing Wu , Jay Tung , Eugene Thorsett , Michael Pleiss , Jeffrey Nissen , Jeffrey Neitz , Lee Latimer , Varghese John , Stephen Freedman , Thomas Britton , James Audia , Jon Reel , Thomas Mabry , Bruce Dressman , Cynthia Cwi , James Droste , Steven Henry , Stacey McDaniel , William Scott , Russell Stucky , Warren Porter

发明人： Jing Wu , Jay Tung , Eugene Thorsett , Michael Pleiss , Jeffrey Nissen , Jeffrey Neitz , Lee Latimer , Varghese John , Stephen Freedman , Thomas Britton , James Audia , Jon Reel , Thomas Mabry , Bruce Dressman , Cynthia Cwi , James Droste , Steven Henry , Stacey McDaniel , William Scott , Russell Stucky , Warren Porter

IPC分类号： A61K31/40 , A61K31/4015 , A61K31/445 , A61K31/55 , A61K38/04 , A61K38/05 , A61P25/28 , C07D223/18 , C07D471/04 , C07D471/06 , C07D471/08

CPC分类号： C07D471/04 , A61K31/40 , A61K31/4015 , A61K31/445 , A61K31/5513 , A61K38/05 , C07C237/22 , C07C2603/32 , C07D223/18 , C07D307/33 , C07D311/76 , C07D471/06 , C07D471/08

摘要： Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

2.

发明授权
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting &bgr;-amyloid peptide release and/or its synthesis by use of such compounds 失效

公开(公告)号：US06579867B2

公开(公告)日：2003-06-17

申请号：US09915379

申请日：2001-07-27

申请人： Jing Wu , Jay S. Tung , Eugene D. Thorsett , Michael A. Pleiss , Jeffrey S. Nissen , Jeffrey Neitz , Lee H. Latimer , Varghese John , Stephen Freedman , Thomas C. Britton , James A. Audia , Jon K. Reel , Thomas E. Mabry , Bruce A. Dressman , James J. Droste , Steven S. Henry , Stacey L. McDaniel , Russell D. Stucky , Warren J. Porter

发明人： Jing Wu , Jay S. Tung , Eugene D. Thorsett , Michael A. Pleiss , Jeffrey S. Nissen , Jeffrey Neitz , Lee H. Latimer , Varghese John , Stephen Freedman , Thomas C. Britton , James A. Audia , Jon K. Reel , Thomas E. Mabry , Bruce A. Dressman , James J. Droste , Steven S. Henry , Stacey L. McDaniel , Russell D. Stucky , Warren J. Porter

IPC分类号： A61K3155

CPC分类号： C07D471/04 , A61K31/40 , A61K31/4015 , A61K31/445 , A61K31/5513 , A61K38/05 , C07C237/22 , C07C2603/32 , C07D223/18 , C07D307/33 , C07D311/76 , C07D471/06 , C07D471/08

摘要： Disclosed are compounds which inhibit &bgr;-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits &bgr;-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.