公开(公告)号：US20070139589A1

公开(公告)日：2007-06-21

申请号：US10598189

申请日：2005-02-23

申请人： Sander Roosendaal ,  Emiel Peeters ,  Johan Lub ,  Bianca Van Der Zande ,  Ciska Doornkamp ,  Dirk Kornelis De Boer ,  Jacob Bruinink

发明人： Sander Roosendaal ,  Emiel Peeters ,  Johan Lub ,  Bianca Van Der Zande ,  Ciska Doornkamp ,  Dirk Kornelis De Boer ,  Jacob Bruinink

IPC分类号： G02F1/1335

CPC分类号： G02F1/133555 ,  G02F1/13363 ,  G02F2001/133565 ,  G02F2202/40 ,  G02F2413/04 ,  G02F2413/08 ,  G02F2413/09

摘要： A transflective liquid crystal display comprising a plurality of pixels, each pixel comprising a liquid crystal layer (3) sandwiched between a front substrate (1) and a back substrate (2), and an optical layer (7) comprising a birefringent material, said pixels being divided into at least one transmissive (5) and at least one reflective subpixel (4), and said optical layer (7) being at least partly sandwiched between the liquid crystal layer (3) and one of said front substrate (1) or back substrate (2), and being patterned into domains (8, 9), each domain covering at least part of a reflective subpixel (4) or at least part of a transmissive subpixel (5).

摘要翻译： 一种半透射型液晶显示器，包括多个像素，每个像素包括夹在前基板（1）和后基板（2）之间的液晶层（3）和包括双折射材料的光学层（7），所述光学层 像素被分成至少一个透射（5）和至少一个反射子像素（4），并且所述光学层（7）至少部分地夹在液晶层（3）和所述前基板（1）中的一个之间， 或背面基板（2），并且被图案化成域（8,9），每个域覆盖反射子像素（4）的至少一部分或透射子像素（5）的至少一部分。

公开(公告)号：US20060177605A1

公开(公告)日：2006-08-10

申请号：US10549025

申请日：2004-03-18

申请人： Johan Lub ,  Bianca Van Der Zande ,  Emiel Peeters

发明人： Johan Lub ,  Bianca Van Der Zande ,  Emiel Peeters

IPC分类号： G02F1/13363 ,  C09K19/38 ,  G02F1/1335 ,  C09K19/02

CPC分类号： G02F1/13363 ,  C09K19/46 ,  C09K2219/03 ,  G02B5/3083 ,  G02F2001/133565 ,  G02F2001/133633 ,  G02F2203/09 ,  G02F2413/01 ,  G02F2413/09 ,  Y10T428/10 ,  Y10T428/1036

摘要： A birefringent optical element comprises a polymerized and/or cross-linked mixture (301) of a liquid crystalline compound and a photo-isomerizable compound. The birefringence of the element can be determined with high precision by manipulating the order parameter and polarization anisotropy of said mixture. For this purpose, the photo-isomerizable compound is converted from a transform to a cis-form during manufacturing by means of irradiation. Preferably the photo-isomerizable compound is a cinnamate compound. The irradiated mixture is polymerized and/or cross-linked after irradiation. The irradiation preferably takes place through a greyscale mask (305) so that within the mixture (301) portions (302R, 302G, 302B) are defined that obtain different birefringence values. The process is for example suitable for manufacturing a retarder layer or compensation foil inside the liquid crystalline cell of a Liquid Crystal Display (LCD) device, and in particular for manufacturing a patterned retarder layer having portions with different retardation, associated with the primary colors of a color LCD device.

摘要翻译： 双折射光学元件包括液晶化合物和光可异构化化合物的聚合和/或交联的混合物（301）。 元件的双折射可以通过操纵所述混合物的阶数参数和偏振各向异性来高精度地确定。 为此目的，通过照射在制造过程中将光可异构化化合物从转化转化为顺式。 优选光可异构化化合物是肉桂酸酯化合物。 被照射的混合物在照射后聚合和/或交联。 照射优选通过灰度级掩模（305）发生，使得在混合物（301）部分（302R，302G，302B）中被限定得到不同的双折射值。 该方法例如适合于在液晶显示器（LCD）器件的液晶单元内部制造延迟器层或补偿箔，特别是用于制造具有不同延迟的部分的图案化延迟器层，其与原色相关联 彩色液晶显示装置。

公开(公告)号：US20070024970A1

公开(公告)日：2007-02-01

申请号：US10578062

申请日：2004-11-02

申请人： Johan Lub ,  Emiel Peeters ,  Dirk Broer

发明人： Johan Lub ,  Emiel Peeters ,  Dirk Broer

IPC分类号： G02B27/28

CPC分类号： G02F1/133528 ,  C09K19/3852 ,  C09K19/60 ,  C09K19/606 ,  C09K2219/03 ,  G02B5/3016 ,  G02F1/1334 ,  G02F1/13725 ,  Y10T428/1041

摘要： A dichroic guest-host polarizer comprises an oriented polymerized liquid crystal host and aligned therewith a dichroic guest. The dichroic ratio of the polarizer is about 15 or more. The polarizer may have a small thickness, be manufactured using a wet deposition method, optionally in accordance with a desired pattern, and be provided on the inside of a liquid crystal cell. Polymerizable liquid crystals having a highly ordered mesophase which may be suitable used to obtain highly oriented polymer films such as polarizer films are disclosed.

摘要翻译： 二向色客体偏振器包括定向聚合的液晶主机并与二向色客体对准。 偏振器的分色比约为15或更大。 偏振器可以具有小的厚度，可以根据期望的图案使用湿式沉积方法制造，并且设置在液晶单元的内部。 公开了具有高度有序的中间相的可聚合液晶，其可适用于获得高定向聚合物膜如偏振片。

公开(公告)号：US08518299B2

公开(公告)日：2013-08-27

申请号：US12830140

申请日：2010-07-02

申请人： Johan Lub ,  Emiel Peeters ,  Dirk Jan Broer

发明人： Johan Lub ,  Emiel Peeters ,  Dirk Jan Broer

IPC分类号： C09K19/20

CPC分类号： G02F1/133528 ,  C09K19/3852 ,  C09K19/60 ,  C09K19/606 ,  C09K2219/03 ,  G02B5/3016 ,  G02F1/1334 ,  G02F1/13725 ,  Y10T428/1041

摘要： A dichroic guest-host polarizer comprises an oriented polymerized liquid crystal host and aligned therewith a dichroic guest. The dichroic ratio of the polarizer is about 15 or more. The polarizer may have a small thickness, be manufactured using a wet deposition method, optionally in accordance with a desired pattern, and be provided on the inside of a liquid crystal cell. Polymerizable liquid crystals having a highly ordered mesophase which may be suitable used to obtain highly oriented polymer films such as polarizer films are disclosed.

摘要翻译： 二向色客体偏振器包括定向聚合的液晶主机并与二向色客体对准。 偏振器的分色比约为15或更大。 偏振器可以具有小的厚度，可以根据期望的图案使用湿式沉积方法制造，并且设置在液晶单元的内部。 公开了具有高度有序的中间相的可聚合液晶，其可适用于获得高定向聚合物膜如偏振片。

公开(公告)号：US07763330B2

公开(公告)日：2010-07-27

申请号：US10578062

申请日：2004-11-02

申请人： Johan Lub ,  Emiel Peeters ,  Dirk Jan Broer

发明人： Johan Lub ,  Emiel Peeters ,  Dirk Jan Broer

IPC分类号： G02F1/1335

CPC分类号： G02F1/133528 ,  C09K19/3852 ,  C09K19/60 ,  C09K19/606 ,  C09K2219/03 ,  G02B5/3016 ,  G02F1/1334 ,  G02F1/13725 ,  Y10T428/1041

摘要： A dichroic guest-host polarizer comprises an oriented polymerized liquid crystal host and aligned therewith a dichroic guest. The dichroic ratio of the polarizer is about 15 or more. The polarizer may have a small thickness, be manufactured using a wet deposition method, optionally in accordance with a desired pattern, and be provided on the inside of a liquid crystal cell. Polymerizable liquid crystals having a highly ordered mesophase which may be suitable used to obtain highly oriented polymer films such as polarizer films are disclosed.

摘要翻译： 二向色客体偏振器包括定向聚合的液晶主机并与二向色客体对准。 偏振器的分色比约为15或更大。 偏振器可以具有小的厚度，可以根据期望的图案使用湿式沉积方法制造，并且设置在液晶单元的内部。 公开了具有高度有序的中间相的可聚合液晶，其可适用于获得高定向聚合物膜如偏振片。

公开(公告)号：US09913921B2

公开(公告)日：2018-03-13

申请号：US14115455

申请日：2012-05-07

申请人： Marc Stefan Robillard ,  Johan Lub ,  Raffaella Rossin ,  Sandra Martina Van Ben Bosch ,  Ronny Mathieu Versteegen

发明人： Marc Stefan Robillard ,  Johan Lub ,  Raffaella Rossin ,  Sandra Martina Van Ben Bosch ,  Ronny Mathieu Versteegen

IPC分类号： A61K51/10 ,  A61K51/04 ,  B82Y5/00 ,  C07D207/46 ,  C07D235/02 ,  C07D245/02 ,  C07D249/16 ,  A61K47/68 ,  A61K49/10

CPC分类号： A61K51/1093 ,  A61K47/6897 ,  A61K49/106 ,  A61K51/041 ,  A61K51/0495 ,  A61K51/0497 ,  B82Y5/00 ,  C07D207/46 ,  C07D235/02 ,  C07D245/02 ,  C07D249/16

摘要： Described is a pretargeting method, and related kits, for targeted medical imaging and/or therapeutics, wherein use is made of abiotic reactive chemical groups that exhibit bio-orthogonal reactivity towards each other. The invention involves the use of [4+2] inverse electron demand (retro) Diels-Alder chemistry in providing the coupling between a Pre-targeting Probe and an Effector Probe. To this end one of these probes comprises an electron-deficient tetrazine or other suitable diene, and the other an E-cyclooctene which has a flattened structure as a result of the position of at least two exocyclic bonds.

公开(公告)号：US08409674B2

公开(公告)日：2013-04-02

申请号：US10567552

申请日：2004-07-26

申请人： Richard Harding ,  Alison Linda May ,  Simon Greenfield ,  Johan Lub ,  Ciska Doornkamp ,  René Theodorus Wegh

发明人： Richard Harding ,  Alison Linda May ,  Simon Greenfield ,  Johan Lub ,  Ciska Doornkamp ,  René Theodorus Wegh

IPC分类号： C09K19/56 ,  G02F1/1337

CPC分类号： B82Y30/00 ,  G02F1/133711 ,  G02F1/133723 ,  G02F2001/133726 ,  Y10T428/1005 ,  Y10T428/1023 ,  Y10T428/31721

摘要： The invention relates to an alignment layer for aligning liquid crystal molecules, with improved adhesion to liquid crystal (LC) films, to a composition containing a precursor material used for the preparation of such a layer, to a laminate comprising such a layer and at least one LC polymer film, and to the use of the alignment layer and the laminate for optical, electrooptical, decorative or security uses and devices, wherein the alignment layer and the precursor material comprise at least one reactive mesogen in monomeric, oligomeric or polymeric form.

摘要翻译： 本发明涉及一种用于将液晶分子对准的取向层与对液晶（LC）膜的粘合性提高到包含用于制备这种层的前体材料的组合物， 一个LC聚合物膜，以及用于光学，电光，装饰或安全用途和装置的对准层和层压材料的使用，其中定向层和前体材料包含单体，低聚或聚合形式的至少一种反应性介晶。

公开(公告)号：US20120039803A1

公开(公告)日：2012-02-16

申请号：US13264526

申请日：2010-04-12

申请人： Marc Stefan Robillard ,  Raffaella Rossin ,  Johan Lub ,  Pascal Renart Verkerk ,  Dirk Burdinski

发明人： Marc Stefan Robillard ,  Raffaella Rossin ,  Johan Lub ,  Pascal Renart Verkerk ,  Dirk Burdinski

IPC分类号： A61K31/444 ,  A61K51/04 ,  A61K49/04 ,  A61K49/10 ,  A61K49/22 ,  A61K49/00 ,  C07D401/14

CPC分类号： B82Y5/00 ,  A61K47/6897 ,  A61K51/0495 ,  A61K51/1027 ,  A61K51/1045

摘要： Described is a pretargeting method, and related kits, for targeted medical imaging and/or therapeutics, wherein use is made of abiotic reactive chemical groups that exhibit bio-orthogonal reactivity towards each other. The invention involves the use of [4+2] inverse electron demand (retro) Diels-Alder chemistry in providing the coupling between a Pre-targeting Probe and an Effector Probe. To this end one of these probes comprises an electron-deficient tetrazine or other suitable diene, and the other an alkene or alkyne dienohile.

摘要翻译： 描述了用于靶向医学成像和/或治疗剂的预靶向方法和相关试剂盒，其中使用对彼此显示出生物正交反应性的非生物反应性化学基团。 本发明涉及使用[4 + 2]反电子需求（复古）Diels-Alder化学来提供预瞄准探针和效应探针之间的耦合。 为此目的，这些探针中的一种包括电子缺乏四嗪或其它合适的二烯，另一种是烯烃或炔烃二酮。

公开(公告)号：US20110165074A1

公开(公告)日：2011-07-07

申请号：US13062742

申请日：2009-09-08

申请人： Holger Gruell ,  Anke De Vries ,  Sander Langereis ,  Johan Lub ,  Erica M.G. Aussems-Custers

发明人： Holger Gruell ,  Anke De Vries ,  Sander Langereis ,  Johan Lub ,  Erica M.G. Aussems-Custers

IPC分类号： A61K51/12 ,  C08F8/32 ,  A61K47/34 ,  A61K49/12

CPC分类号： C08G81/025 ,  A61K9/107 ,  A61K9/1075 ,  A61K9/1273 ,  A61K9/5146 ,  A61K49/0414 ,  A61K49/126 ,  A61K49/1806 ,  A61K49/1812 ,  A61K49/1818 ,  A61K51/06 ,  A61K51/065 ,  A61K51/1217 ,  A61K51/1237 ,  A61K51/1251

摘要： Described are amphiphilic polymers that are provided with chelating moieties. The amphiphilic polymers are block copolymers comprising a hydrophilic block and a hydrophobic block, with the chelating moieties linked to the end-group of the hydrophilic block. The disclosed polymers are capable of self-assembly into structures such as micelles and polymersomes. With suitable metals present in the form of coordination complexes with 5 the chelating moieties, the chelating amphiphilic polymers of the invention are suitable for use in various imaging techniques requiring metal labeling, such as MRI (T 1/T 2 weighted contrast agents or CEST contrast agents) SPECT, PET or Spectral CT.

摘要翻译： 描述的是具有螯合部分的两亲性聚合物。 两亲聚合物是包含亲水嵌段和疏水嵌段的嵌段共聚物，螯合部分连接到亲水嵌段的端基。 所公开的聚合物能够自组装成结构如胶束和聚合物囊泡。 使用与5个螯合部分配位络合物形式的合适金属，本发明的螯合两亲性聚合物适用于需要金属标记的各种成像技术，例如MRI（T 1 / T 2加权造影剂或CEST对比度 药剂）SPECT，PET或光谱CT。

公开(公告)号：US20060040068A1

公开(公告)日：2006-02-23

申请号：US10533059

申请日：2003-10-07

申请人： Rene Wegh ,  Johan Lub

发明人： Rene Wegh ,  Johan Lub

IPC分类号： C09K19/00

CPC分类号： C09K19/3857 ,  G02B5/3016 ,  G02F1/133536 ,  G02F2001/133543 ,  Y10T428/1005

摘要： The invention pertains to a method of manufacturing a layer of a cholesterically ordered polymer material, in which the material is oriented in such a way that the axis of the molecular helix of the cholesterically ordered material extends transversely to the layer, wherein the method comprises the steps: a) providing a layer comprising a cholesterically ordered mixture of a low-molecular weight polymerizable material and a high-molecular weight material, which high-molecular weight material comprises a quantity of a convertible group, which in its non-converted and in its converted state determines the pitch or the material to a different extent, the conversion of said high-molecular weight material being inducible by radiation, and the layer absorbs said radiation; b) irradiating the layer to convert at least a part of the convertible groups it the irradiated parts of the layer; c) letting at least the low-molecular weight material reorient to form the required helical structure; d) at least partially polymerizing and/or cross-linking the low-molecular weight material with itself and/or with the high-molecular weight material to freeze in the formed structure.

摘要翻译： 本发明涉及一种制造胆甾醇有序聚合物材料层的方法，其中材料以这样一种方式取向，使得胆甾醇排序材料的分子螺旋轴线横向于该层延伸，其中该方法包括 步骤：a）提供包含低分子量可聚合材料和高分子量材料的胆甾醇排序混合物的层，该高分子量材料包含一定量的可转化基团，其在其未转化和 其转化状态决定了沥青或材料的不同程度，所述高分子量材料的转化可通过辐射诱导，并且该层吸收所述辐射; b）照射该层以将其所辐照的部分的至少一部分可转换基团转化; c）使至少低分子量材料重新取向以形成所需的螺旋结构; d）至少部分地将低分子量材料与其自身和/或与高分子量材料聚合和/或交联以在形成的结构中冷冻。