公开(公告)号：US11067564B2

公开(公告)日：2021-07-20

申请号：US15570362

申请日：2016-04-29

Applicant: INDUSTRY ACADEMIC COOPERATION FOUNDATION KEIMYUNG UNIVERSITY ,  KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Yun Seok Heo ,  Dae-Kyu Song ,  Su Jeong Shin ,  Min Ho Yang ,  Jae-hoon Han ,  Tae Jae Lee ,  Seok Jae Lee

IPC: G01N33/49 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1468 ,  G01N33/66 ,  G01N27/02 ,  G01N33/487 ,  G01N33/68 ,  G01N27/327

Abstract: A portable insulin resistance diagnosis device includes: a housing capable of being grasped by an outer periphery thereof and comprising a space formed therein; a sensor unit which protrudes towards the outside of the housing and detects glucose and proteins in blood when a blood sample of a target specimen is dropped on the sensor unit, a diagnosis unit, which is provided inside the housing, amplifying an electrical signal generated according to concentrations of the blood glucose and proteins detected in the sensor unit, converting the electrical signal into a digital signal, and determining whether insulin resistance is normal; and a display unit, which is provided on an external surface of the housing, displaying whether insulin resistance analyzed in the diagnosis unit is normal.

公开(公告)号：US12229951B2

公开(公告)日：2025-02-18

申请号：US17556971

申请日：2021-12-20

Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Kyoung Gyun Lee ,  Sung Gap Im ,  Seok Jae Lee ,  Youn Seong Song ,  Yoo Min Park ,  Nam Ho Bae

IPC: G06T7/00 ,  G01N21/64 ,  G01N33/53 ,  G06T7/77 ,  G06V10/75

Abstract: Provided are a device for a digital assay of targets according to an exemplary embodiment of the present disclosure and a method using the same. The digital assay method of targets according to the exemplary embodiment of the present disclosure includes acquiring an image for a plurality of microdroplets, predicting at least one region based on the image for the plurality of microdroplets using an artificial neural network-based prediction model configured to segment at least one region among positive microdroplets, negative microdroplets, and atypical microdroplets, with the image for the plurality of microdroplets as an input, determining a number for the plurality of microdroplets based on the at least one region, and providing quantitative data of targets based on the number for the plurality of microdroplets.

公开(公告)号：US20230417667A1

公开(公告)日：2023-12-28

申请号：US18035202

申请日：2021-11-01

Applicant: The General Hospital Corporation ,  Korea Advanced Institute of Science and Technology

Inventor： Hakho Lee ,  Hyungsoon Im ,  Nam Ho Bae ,  Seok Jae Lee ,  Kyoung Gyun Lee ,  Kwang Hee Kim ,  Kil Sun Roh

IPC: G01N21/552 ,  G01N21/41

CPC classification number: G01N21/554 ,  G01N21/41 ,  G01N2021/5903

Abstract: Methods, systems, and apparatus, for a sensor-chip device for performing analysis on target substances. In one aspect, the sensor-chip assembly includes a chip body including a substrate, at least one metal layer formed on the substrate, and nanoholes formed in the metal layer, a base having an accommodating portion for accommodating the chip body, and a fixing member fixing the chip body accommodated in the accommodating portion by being coupled to the base.

公开(公告)号：US11666902B2

公开(公告)日：2023-06-06

申请号：US16978438

申请日：2019-07-25

Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Seok Jae Lee ,  Moon Keun Lee ,  Nam Ho Bae ,  Tae Jae Lee ,  Kyoung Gyun Lee ,  Yoo Min Park

IPC: B01L3/00

CPC classification number: B01L3/5027 ,  B01L3/502715 ,  B01L2200/027 ,  B01L2200/028 ,  B01L2300/0861 ,  B01L2300/0883 ,  B01L2300/161

Abstract: A modular fluidic chip includes a body configured to have at least one flow channel formed in an inside thereof and be connected to another modular fluidic chip to allow the at least one flow channel to communicate with a flow channel provided in the other modular fluidic chip. A fluidic chip capable of performing one function is formed in the form of a module, whereby a fluidic flow system of various structures can be implemented without restriction in shape or size by connecting a plurality of fluidic chips capable of performing different functions as necessary. Through this, various and accurate experimental data can be obtained, and when a specific portion is deformed or damaged, only the fluidic chip corresponding thereto can be replaced, thereby reducing manufacture and maintenance costs.

公开(公告)号：US11618018B2

公开(公告)日：2023-04-04

申请号：US17056416

申请日：2019-07-25

Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Moon Keun Lee ,  Seok Jae Lee ,  Nam Ho Bae ,  Tae Jae Lee ,  Kyoung Gyun Lee ,  Yoo Min Park

IPC: B01L3/00

Abstract: A modular fluid chip according to an embodiment of the present disclosure includes a body including at least one first hole which allows fluid to flow therethrough; and a housing receiving the body therein, and including a second hole which corresponds to the at least one first hole and allows the fluid to flow therethrough, and a fluid connection part which is connectable to another modular fluid chip.