公开(公告)号：US20240117389A1

公开(公告)日：2024-04-11

申请号：US18470284

申请日：2023-09-19

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Youngsoon UM ,  Deurim YUN ,  Sun Mi LEE ,  Gyeongtaek GONG ,  Ja Kyong KO ,  Jung Ho AHN

IPC: C12P7/40 ,  C12P7/02 ,  C12P7/16 ,  C12P7/52

CPC classification number: C12P7/40 ,  C12P7/02 ,  C12P7/16 ,  C12P7/52

Abstract: The present disclosure is to provide a method capable of producing an organic acid in high yield from an acetic acid strain using synthesis gas as a substrate. According to the present disclosure, the productivity of metabolites with C2 to C6 carbon atoms derived from synthesis gas and the selectivity of hexanoic acid production among metabolites can be improved through a first fermentation step of simultaneously providing a substrate comprising synthesis gas and sugar; and a second fermentation step of semi-mixotrophic fermentation of providing only the substrate comprising the synthesis gas. Therefore, the disclosure can contribute to sustainable chemical production using synthesis gas.

公开(公告)号：US20230242948A1

公开(公告)日：2023-08-03

申请号：US17823034

申请日：2022-08-29

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Sun Mi LEE ,  Yeon-Ho CHOI ,  Gyeongtaek GONG ,  Ja Kyoung KO ,  Jung Ho AHN ,  Youngsoon UM

IPC: C12P7/6409 ,  C12N9/10 ,  C12N1/16

CPC classification number: C12P7/6409 ,  C12N9/1029 ,  C12Y203/0102 ,  C12N1/16

Abstract: The present specification describes a culture of a microorganism, which comprises an increased content of oleic acid, or a microbial oil comprising the same. In addition, the present specification describes a method for producing oleic acid and lipids comprising the same by culturing a microorganism. Since the present disclosure enables the production of lipids comprising oleic acid at a high concentration without genetic manipulation of a lipid-producing microorganism, it may be utilized in various industrial fields requiring oleic acid, such as foods, cosmetic materials, biofuels, etc.

公开(公告)号：US20230313241A1

公开(公告)日：2023-10-05

申请号：US18059330

申请日：2022-11-28

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Ja Kyong KO ,  Youngyun JO ,  Gyeongtaek GONG ,  Jung Ho AHN ,  Sun Mi LEE ,  Youngsoon UM

IPC: C12P7/625 ,  C12N15/74 ,  C12N9/10

CPC classification number: C12P7/625 ,  C12N15/74 ,  C12N9/1022 ,  C12Y202/01006 ,  C12N9/1029 ,  C12Y203/01009 ,  C12Y203/01182

Abstract: The present disclosure provides a recombinant microorganism for producing PHBV, a method for preparing the same, and a method for producing PHBV using the microorganism. The present disclosure may provide a recombinant microorganism capable of producing PHBV, which is a biodegradable plastic material with superior physical properties, directly from an inexpensive single carbon source with high efficiency without supplementation of organic acid. The present disclosure can enhance the utilization of PHA, which is expensive and has limited physical properties, and can also provide a technology more effective for industrialization using an inexpensive single carbon source. The PHBV produced according to an exemplary embodiment of the present disclosure can be used not only for general-purpose inexpensive products such as ecofriendly packing materials but also as a high-value-added medical biopolymer.