公开(公告)号：US20190064175A1

公开(公告)日：2019-02-28

申请号：US15954858

申请日：2018-04-17

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Tae Song Kim ,  Rhokyun Kwak ,  Won Bae Han

IPC: G01N33/68

Abstract: Disclosed area methods for fabricating three-dimensional artificial lipid biomembrane structure arrays with sufficient reaction area and high stability on a substrate in a simpler and easier manner. The methods use constituent lipids of real cell membranes and a plurality of microwells formed on a substrate. The methods can more effectively provide biomimetic three-dimensional lipid membrane structure arrays that possess structural and/or functional properties of cell membranes.

公开(公告)号：US11672435B2

公开(公告)日：2023-06-13

申请号：US16691006

申请日：2019-11-21

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Hyunjung Yi ,  Tae-Hyung Kang ,  Sunho Kim ,  In-Suk Choi ,  Rhokyun Kwak ,  Sangha Kim ,  Jina Choi

IPC: G08B21/04 ,  A61B5/024 ,  A61B5/00

CPC classification number: A61B5/024 ,  A61B5/6833 ,  A61B2560/0412

Abstract: Provided is a sensor patch configured to be attached to the skin of a user. The sensor patch may include: at least one opening; and a frame surrounding the at least one opening, wherein the frame may include at least one senor configured to measure a biosignal of the user. Therefore, since the at least one sensor for measuring a biosignal is provided on the frame surrounding at least one opening, it may be possible to continuously obtain a biosignal of the user for a long period of time.

公开(公告)号：US10585022B2

公开(公告)日：2020-03-10

申请号：US15216938

申请日：2016-07-22

Applicant: Korea Institute of Science and Technology

Inventor： Rhokyun Kwak ,  Ji Yoon Kang ,  Jaesung Park ,  Siwoo Cho

IPC: C12Q1/68 ,  G01N1/40 ,  G01N27/447 ,  C12Q1/6806 ,  C12Q1/00

Abstract: Provided are an extracellular vesicle collecting apparatus using an electrode and a porous membrane and a method for using the same. The extracellular vesicle collecting apparatus includes i) an upper frame in which a pair of through holes is disposed so that a buffer solution flows therethrough, ii) a buffer tube which is inserted in the through holes and in which the buffer solution flows, iii) a positive electrode disposed on the upper frame, iv) a porous membrane located below the upper frame, v) a spacer which is located below the porous membrane and has a hollow space disposed therein, vi) a plurality of guide tubes through which a blood flows in the hollow space, vii) a lower frame which is coupled to the upper frame to be opposite to the upper frame and receives the porous membrane and the spacer therein, and viii) a negative electrode provided below the lower frame. Extracellular vesicles contained in the blood are collected by the porous membrane.

公开(公告)号：US09753027B2

公开(公告)日：2017-09-05

申请号：US14575129

申请日：2014-12-18

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Kyoseon Hwang ,  Tae Song Kim ,  Rhokyun Kwak ,  Won Woo Cho ,  Myung Sic Chae

IPC: G01N29/00 ,  G01H11/08 ,  H01L41/08 ,  G01N33/53 ,  G01N33/543 ,  G01N29/02 ,  G01N29/036

CPC classification number: G01N33/5302 ,  G01N29/022 ,  G01N29/036 ,  G01N33/54373 ,  G01N33/5438 ,  G01N2291/0427

Abstract: The present disclosure relates to a cantilever sensor, and a biosensor having the same, wherein the cantilever sensor including a slit formed on a flat board and a cantilever formed by the slit, a first electrode formed on the cantilever, and a second electrode formed on the flat board countered to the first electrode about the slit, wherein the electrodes are formed on the cantilever sensor having the slit, whereby sensing can be conducted by an electric method, through which the sensor can be effectively miniaturized.