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    Preparation of electrophoresis gels, and related devices, systems, and methods
    2.
    发明授权
    Preparation of electrophoresis gels, and related devices, systems, and methods 有权

    公开(公告)号：US10359396B2

    公开(公告)日：2019-07-23

    申请号：US15349106

    申请日：2016-11-11

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： Kyle Bulloch ,  Thomas Diller

    IPC: G01N27/447

    Abstract: An apparatus for preparation of an electrophoresis slab gel may include a base having an opening configured to receive a cassette configured to contain an electrophoresis slab gel, a clamping mechanism configured to move relative to the base between an open position in which the clamping mechanism permits insertion of a cassette into the base, and a closed position in which the clamping mechanism is configured to clamp a cassette received in the base, a compressible pad operatively coupled to the clamping mechanism in a position to compress against a cassette received in the base in the closed position of the clamping mechanism. The cassette may include a first plate and a second plate, and a spacer mechanism separate from each of the first and second plates, the spacer mechanism configured to be positioned between the inner faces of the first plate and the second plate. When subjected to a clamping force exerted on the outer faces of the first and second plates, the spacer mechanism is configured to maintain a separation distance between the inner faces of the first and second plates, and provide a seal to prevent leakage of an electrophoresis gel solution introduced between the plates.

    Electrophoresis gel cassette
    6.
    外观设计
    Electrophoresis gel cassette 有权

    公开(公告)号：USD1041679S1

    公开(公告)日：2024-09-10

    申请号：US29733570

    申请日：2020-05-04

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Designer： Kyle Bulloch ,  Thomas Diller ,  Xin Mathers

    Abstract: This application is related to U.S. Design patent application Ser. No. 29/545,629 file Nov. 13, 2015; and to U.S. Design patent application Ser. No. 29/545,637 filed Nov. 13, 2015 (now U.S. Design Pat. No. D792,603 issued Jul. 18, 2017), and U.S. Design patent application Ser. No. 29/596,358 filed Mar. 7, 2017, the entire contents of each of which are incorporated by reference herein.
    FIG. 1 is a front perspective view of an electrophoresis gel cassette showing our new design.
    FIG. 2 is a back perspective thereof.
    FIG. 3 is a front view thereof.
    FIG. 4 is a back view thereof.
    FIG. 5 is a right side view thereof.
    FIG. 6 is a left side view thereof.
    FIG. 7 is a top view thereof; and,
    FIG. 8 is a bottom view thereof.
    The broken lines in the figures show unclaimed portions of the electrophoresis gel cassette and form no part of the claimed design.
    The oblique shade lines depict surface transparency.

    RAPID PROTEIN LABELING AND ANALYSIS
    8.
    发明申请
    RAPID PROTEIN LABELING AND ANALYSIS 审中-公开

    公开(公告)号：US20160054327A1

    公开(公告)日：2016-02-25

    申请号：US14688986

    申请日：2015-04-16

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： Thomas Diller ,  Bethany Sutton ,  George Hanson ,  Timothy Updyke

    IPC: G01N33/58

    CPC classification number: G01N33/582 ,  B33Y80/00 ,  G01N33/6803 ,  G01N2550/00

    Abstract: The present invention provides methods and compositions for labeling, separating and analyzing proteins, particularly a specific protein of interest within a cell lysate or in a mixture of proteins. The proteins are labeled with an amine reactive or thiol reactive fluorescent dye, or an amine reactive fluorogenic reagent that becomes fluorescent upon reacting to amine groups located on the protein. Following the labeling step, the proteins within the mixture can be separated and analyzed. In a further embodiment, a tag binding fluorogenic reagent that can bind to a tag on a tagged protein is added to specifically label the protein of interest.

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