公开(公告)号：US20130131496A1

公开(公告)日：2013-05-23

申请号：US13749351

申请日：2013-01-24

Applicant: MRI Interventions, Inc.

Inventor： Kimble L. Jenkins ,  Peter Piferi ,  Kamal Vij ,  Daniele Ghidoli ,  Jesse Flores ,  Parag V. Karmarkar ,  Rajesh Pandey

IPC: A61B5/06 ,  A61B5/00 ,  A61B5/053 ,  A61B18/02 ,  A61M25/01 ,  A61M5/00 ,  A61B5/055 ,  A61B18/18

CPC classification number: A61B5/062 ,  A61B5/0044 ,  A61B5/042 ,  A61B5/0422 ,  A61B5/053 ,  A61B5/055 ,  A61B5/065 ,  A61B5/415 ,  A61B5/418 ,  A61B18/02 ,  A61B18/18 ,  A61B34/10 ,  A61B34/20 ,  A61B2090/365 ,  A61B2090/374 ,  A61B2090/3954 ,  A61M5/00 ,  A61M25/01 ,  A61M25/0127 ,  A61M29/00 ,  A61M2025/0089 ,  A61M2025/0166 ,  A61M2025/0681 ,  A61M2025/09175 ,  G01R33/286 ,  G01R33/287

Abstract: An MRI-compatible catheter that reduces localized heating due to MR scanner-induced currents includes an elongated flexible shaft having a distal end portion and an opposite proximal end portion. A handle is attached to the proximal end portion and includes an electrical connector interface configured to be in electrical communication with an MRI scanner. One or more RF tracking coils are positioned adjacent the distal end portion of the shaft. Each RF tracking coil includes a conductive lead, such as a coaxial cable, that extends between the RF tracking coil and the electrical connector interface and electrically connects the RF tracking coil to an MRI scanner. In some embodiments of the present invention, the conductive lead has a length sufficient to define an odd harmonic/multiple of a quarter wavelength of the operational frequency of the MRI Scanner, and/or includes a series of pre-formed back and forth segments along its length.

Abstract translation: 减少由于MR扫描器感应电流引起的局部加热的MRI兼容导管包括具有远端部分和相对近端部分的细长柔性轴。 手柄附接到近端部分并且包括被配置为与MRI扫描仪电连通的电连接器接口。 一个或多个RF跟踪线圈定位在轴的远端部分附近。 每个RF跟踪线圈包括在RF跟踪线圈和电连接器接口之间延伸的导电引线，例如同轴电缆，并将RF跟踪线圈电连接到MRI扫描器。 在本发明的一些实施例中，导电引线具有足以限定MRI扫描器的工作频率的四分之一波长的奇次谐波/倍数的长度，和/或包括一系列预先形成的前后段 它的长度。

公开(公告)号：US09192393B2

公开(公告)日：2015-11-24

申请号：US13788647

申请日：2013-03-07

Applicant: MRI Interventions, Inc.

Inventor： Peter Piferi ,  Daniele Ghidoli

IPC: A61B17/16

CPC classification number: A61B17/16 ,  A61B17/1624 ,  B23B45/06

Abstract: A surgical, manually operated, hand-held MRI-compatible drill for drilling though target bone of a patient includes: a housing; a ring gear held in the housing; a hand crank attached to ring gear and the housing; a pinion gear held in the housing in cooperating alignment with the ring gear; an elongate shaft attached to the pinion on one end portion and to a chuck support on an opposing end portion; a chuck attached to the chuck support held; and jaws attached to the chuck support and residing in the chuck adapted to hold a drill bit. The drill is light-weight. The components can all be polymeric.

Abstract translation: 一种外科手动操作的手持式MRI兼容钻头，用于穿过患者的目标骨骼，包括：壳体; 保持在壳体中的齿圈; 连接到齿圈和壳体的手动曲柄; 保持在壳体中的与齿圈配合对准的小齿轮; 在一个端部附接到小齿轮的细长轴和在相对的端部上的卡盘支撑件; 夹持在卡盘支架上的卡盘; 以及附接到卡盘支撑件并且驻留在适于保持钻头的卡盘中的卡爪。 钻头重量轻。 组分都可以是聚合物。

公开(公告)号：US20130123598A1

公开(公告)日：2013-05-16

申请号：US13738621

申请日：2013-01-10

Applicant: MRI Interventions, Inc.

Inventor： Kimble L. Jenkins ,  Peter Piferi ,  Kamal Vij ,  Daniele Ghidoli ,  Jesse Flores

IPC: A61B5/042 ,  A61B5/00 ,  A61B18/18 ,  A61B5/055

CPC classification number: A61B5/062 ,  A61B5/0044 ,  A61B5/042 ,  A61B5/0422 ,  A61B5/053 ,  A61B5/055 ,  A61B5/065 ,  A61B5/415 ,  A61B5/418 ,  A61B18/02 ,  A61B18/18 ,  A61B34/10 ,  A61B34/20 ,  A61B2090/365 ,  A61B2090/374 ,  A61B2090/3954 ,  A61M5/00 ,  A61M25/01 ,  A61M25/0127 ,  A61M29/00 ,  A61M2025/0089 ,  A61M2025/0166 ,  A61M2025/0681 ,  A61M2025/09175 ,  G01R33/286 ,  G01R33/287

Abstract: An MRI-compatible catheter includes an elongated flexible shaft having opposite distal and proximal end portions. A handle is attached to the proximal end portion and includes an actuator in communication with the shaft distal end portion that is configured to articulate the shaft distal end portion. The distal end portion of the shaft may include an ablation tip and includes at least one RF tracking coil positioned adjacent the ablation tip that is electrically connected to an MRI scanner. The at least one RF tracking coil is electrically connected to a circuit that reduces coupling when the at least one RF tracking coil is exposed to an MRI environment. Each RF tracking coil is a 1-10 turn solenoid coil, and has a length along the longitudinal direction of the catheter of between about 0.25 mm and about 4 mm.

Abstract translation: MRI兼容导管包括具有相对的远端和近端部分的细长柔性轴。 手柄附接到基端部，并且包括与轴远端部连通的致动器，该致动器构造成铰接轴远端部。 轴的远端部分可以包括消融尖端，并且包括邻近消融尖端定位的至少一个RF跟踪线圈，其被电连接到MRI扫描器。 当至少一个RF跟踪线圈暴露于MRI环境时，至少一个RF跟踪线圈电连接到减少耦合的电路。 每个RF跟踪线圈是1-10圈电磁线圈，并且沿着导管的纵向方向具有在约0.25mm和约4mm之间的长度。

公开(公告)号：US08886288B2

公开(公告)日：2014-11-11

申请号：US13738621

申请日：2013-01-10

Applicant: MRI Interventions, Inc.

Inventor： Kimble L. Jenkins ,  Peter Piferi ,  Kamal Vij ,  Daniele Ghidoli ,  Jesse Flores

IPC: A61B5/05 ,  A61B5/06 ,  A61B5/055 ,  A61B5/00 ,  A61M25/01 ,  G01R33/28 ,  A61B5/042 ,  A61B18/18 ,  A61B5/053 ,  A61B18/02 ,  A61M5/00 ,  A61B19/00 ,  A61M29/00 ,  A61M25/00 ,  A61M25/06 ,  A61M25/09

CPC classification number: A61B5/062 ,  A61B5/0044 ,  A61B5/042 ,  A61B5/0422 ,  A61B5/053 ,  A61B5/055 ,  A61B5/065 ,  A61B5/415 ,  A61B5/418 ,  A61B18/02 ,  A61B18/18 ,  A61B34/10 ,  A61B34/20 ,  A61B2090/365 ,  A61B2090/374 ,  A61B2090/3954 ,  A61M5/00 ,  A61M25/01 ,  A61M25/0127 ,  A61M29/00 ,  A61M2025/0089 ,  A61M2025/0166 ,  A61M2025/0681 ,  A61M2025/09175 ,  G01R33/286 ,  G01R33/287

Abstract: An MRI-compatible catheter includes an elongated flexible shaft having opposite distal and proximal end portions. A handle is attached to the proximal end portion and includes an actuator in communication with the shaft distal end portion that is configured to articulate the shaft distal end portion. The distal end portion of the shaft may include an ablation tip and includes at least one RF tracking coil positioned adjacent the ablation tip that is electrically connected to an MRI scanner. The at least one RF tracking coil is electrically connected to a circuit that reduces coupling when the at least one RF tracking coil is exposed to an MRI environment. Each RF tracking coil is a 1-10 turn solenoid coil, and has a length along the longitudinal direction of the catheter of between about 0.25 mm and about 4 mm.

Abstract translation: MRI兼容导管包括具有相对的远端和近端部分的细长柔性轴。 手柄附接到基端部，并且包括与轴远端部连通的致动器，该致动器构造成铰接轴远端部。 轴的远端部分可以包括消融尖端，并且包括邻近消融尖端定位的至少一个RF跟踪线圈，其被电连接到MRI扫描器。 当至少一个RF跟踪线圈暴露于MRI环境时，至少一个RF跟踪线圈电连接到减少耦合的电路。 每个RF跟踪线圈是1-10圈电磁线圈，并且沿着导管的纵向方向具有在约0.25mm和约4mm之间的长度。

公开(公告)号：US20140257086A1

公开(公告)日：2014-09-11

申请号：US13789868

申请日：2013-03-08

Applicant: MRI INTERVENTIONS, INC.

Inventor： Daniele Ghidoli ,  Kamal Vij

IPC: A61B5/055

CPC classification number: A61B5/055 ,  A61M25/0015 ,  G01R33/287 ,  G01R33/34084 ,  Y10T29/49016

Abstract: Intrabody MRI-compatible medical devices with a rigid stylet body with opposing distal and proximal ends with a wall enclosing at least one cavity extending therebetween. The stylet body has first and second laterally spaced apart and opposing external longitudinally extending recessed surfaces and at least one pair of transversely spaced apart apertures extending through the wall and at least one conductor having a length that extends through the cavity then exits the cavity to define at least one external loop extending between the distal end of the stylet body and the pair of transversely spaced apart apertures. First and second legs of each loop snugly abut a respective first and second recessed surface of the stylet body to thereby cooperate with the stylet body to define a substantially cylindrical shape. The at least one conductor with the at least one loop is configured to act as an MRI antenna.

Abstract translation: 具有刚性探针本体的体内MRI兼容的医疗装置，其具有相对的远端和近端，其中包围至少一个在其间延伸的腔的壁。 探针体具有第一和第二横向间隔开并且相对的外部纵向延伸的凹面和延伸穿过该壁的至少一对横向间隔开的孔，并且具有延伸穿过空腔的长度的至少一个导体然后离开空腔以限定 至少一个在探针体主体的远端和一对横向间隔开的孔之间延伸的外环。 每个环的第一和第二腿紧密地邻接探针体的相应的第一和第二凹入表面，从而与探针体配合以限定基本上圆柱形的形状。 具有至少一个环的至少一个导体被配置为用作MRI天线。

公开(公告)号：US20130325012A1

公开(公告)日：2013-12-05

申请号：US13788647

申请日：2013-03-07

Applicant: MRI INTERVENTIONS, INC.

Inventor： Peter Piferi ,  Daniele Ghidoli

IPC: A61B17/16

CPC classification number: A61B17/16 ,  A61B17/1624 ,  B23B45/06

Abstract: A surgical, manually operated, hand-held MRI-compatible drill for drilling though target bone of a patient includes: a housing; a ring gear held in the housing; a hand crank attached to ring gear and the housing; a pinion gear held in the housing in cooperating alignment with the ring gear; an elongate shaft attached to the pinion on one end portion and to a chuck support on an opposing end portion; a chuck attached to the chuck support held; and jaws attached to the chuck support and residing in the chuck adapted to hold a drill bit. The drill is light-weight. The components can all be polymeric.

Abstract translation: 一种外科手动操作的手持式MRI兼容钻头，用于穿过患者的目标骨骼，包括：壳体; 保持在壳体中的齿圈; 连接到齿圈和壳体的手动曲柄; 保持在壳体中的与齿圈配合对准的小齿轮; 在一个端部附接到小齿轮的细长轴和在相对的端部上的卡盘支撑件; 夹持在卡盘支架上的卡盘; 以及附接到卡盘支撑件并且驻留在适于保持钻头的卡盘中的卡爪。 钻头重量轻。 组分都可以是聚合物。

公开(公告)号：US09078588B2

公开(公告)日：2015-07-14

申请号：US13789868

申请日：2013-03-08

Applicant: MRI Interventions, Inc.

Inventor： Daniele Ghidoli ,  Kamal Vij

IPC: A61B5/055 ,  A61M25/00 ,  G01R33/34 ,  H01P11/00 ,  H01Q13/00 ,  G01R33/28

CPC classification number: A61B5/055 ,  A61M25/0015 ,  G01R33/287 ,  G01R33/34084 ,  Y10T29/49016

Abstract: Intrabody MRI-compatible medical devices with a rigid stylet body with opposing distal and proximal ends with a wall enclosing at least one cavity extending therebetween. The stylet body has first and second laterally spaced apart and opposing external longitudinally extending recessed surfaces and at least one pair of transversely spaced apart apertures extending through the wall and at least one conductor having a length that extends through the cavity then exits the cavity to define at least one external loop extending between the distal end of the stylet body and the pair of transversely spaced apart apertures. First and second legs of each loop snugly abut a respective first and second recessed surface of the stylet body to thereby cooperate with the stylet body to define a substantially cylindrical shape. The at least one conductor with the at least one loop is configured to act as an MRI antenna.

Abstract translation: 具有刚性探针本体的体内MRI兼容的医疗装置，其具有相对的远端和近端，其中包围至少一个在其间延伸的腔的壁。 探针体具有第一和第二横向间隔开并且相对的外部纵向延伸的凹面和延伸穿过该壁的至少一对横向间隔开的孔，并且具有延伸穿过空腔的长度的至少一个导体然后离开空腔以限定 至少一个在探针体主体的远端和一对横向间隔开的孔之间延伸的外环。 每个环的第一和第二腿紧密地邻接探针体的相应的第一和第二凹入表面，从而与探针体配合以限定基本上圆柱形的形状。 具有至少一个环的至少一个导体被配置为用作MRI天线。

公开(公告)号：US20140066750A1

公开(公告)日：2014-03-06

申请号：US13801190

申请日：2013-03-13

Applicant: MRI INTERVENTIONS, INC.

Inventor： Peter Piferi ,  Daniele Ghidoli ,  Rajesh Pandey ,  Jesse Flores

IPC: A61B19/00 ,  A61B5/055

CPC classification number: A61B19/201 ,  A61B5/055 ,  A61B90/11 ,  A61B2017/00911 ,  A61B2017/3407 ,  A61B2090/3954

Abstract: An MRI-guided interventional system for use with a patient and an interventional device includes a base, a trajectory guide frame, and a mounting device. The base is configured to be secured to a body of the patient. The trajectory guide frame includes a targeting cannula. The targeting cannula has an elongate guide bore extending axially therethrough, defining a trajectory axis, and being configured to guide placement of the interventional device. The trajectory guide frame is operable to move the targeting cannula relative to the base to position the trajectory axis to a desired intrabody trajectory to guide placement of the interventional device in vivo. A plurality of patient engagement structures are provided on the base and are configured to penetrate tissue of the body and to space the base apart from the tissue. The system further includes a plurality of fasteners configured to secure the base to the body.

Abstract translation: 用于患者和介入装置的MRI引导介入系统包括基座，轨迹引导框架和安装装置。 基座构造成固定到患者的身体。 轨迹引导框架包括靶向插管。 靶向套管具有轴向延伸穿过其中的细长导向孔，其限定轨迹轴线，并且被配置为引导介入装置的放置。 轨迹引导框架可操作以相对于底座移动目标套管，以将轨迹轴定位到期望的体内轨迹，以引导介入装置在体内的放置。 多个患者接合结构设置在基座上并被构造成穿透身体的组织并且使基部与组织分开。 该系统还包括多个紧固件，其被配置成将基座固定到主体上。

公开(公告)号：US09192446B2

公开(公告)日：2015-11-24

申请号：US13801190

申请日：2013-03-13

Applicant: MRI Interventions, Inc.

Inventor： Peter Piferi ,  Daniele Ghidoli ,  Rajesh Pandey ,  Jesse Flores

IPC: A61B19/00 ,  A61B5/055 ,  A61B17/00 ,  A61B17/34

CPC classification number: A61B19/201 ,  A61B5/055 ,  A61B90/11 ,  A61B2017/00911 ,  A61B2017/3407 ,  A61B2090/3954

Abstract: An MRI-guided interventional system for use with a patient and an interventional device includes a base, a trajectory guide frame, and a mounting device. The base is configured to be secured to a body of the patient. The trajectory guide frame includes a targeting cannula. The targeting cannula has an elongate guide bore extending axially therethrough, defining a trajectory axis, and being configured to guide placement of the interventional device. The trajectory guide frame is operable to move the targeting cannula relative to the base to position the trajectory axis to a desired intrabody trajectory to guide placement of the interventional device in vivo. A plurality of patient engagement structures are provided on the base and are configured to penetrate tissue of the body and to space the base apart from the tissue. The system further includes a plurality of fasteners configured to secure the base to the body.

Abstract translation: 用于患者和介入装置的MRI引导介入系统包括基座，轨迹引导框架和安装装置。 基座构造成固定到患者的身体。 轨迹引导框架包括靶向插管。 靶向套管具有轴向延伸穿过其中的细长导向孔，其限定轨迹轴线，并且被配置为引导介入装置的放置。 轨迹引导框架可操作以相对于底座移动目标套管，以将轨迹轴定位到期望的体内轨迹，以引导介入装置在体内的放置。 多个患者接合结构设置在基座上并被构造成穿透身体的组织并且使基部与组织分开。 该系统还包括多个紧固件，其被配置成将基座固定到主体上。

公开(公告)号：US08825133B2

公开(公告)日：2014-09-02

申请号：US13749351

申请日：2013-01-24

Applicant: MRI Interventions, Inc.

Inventor： Kimble L. Jenkins ,  Peter Piferi ,  Kamal Vij ,  Daniele Ghidoli ,  Jesse Flores ,  Parag V. Karmarkar ,  Rajesh Pandey

IPC: A61B5/05 ,  A61B5/00 ,  A61B5/06 ,  A61B18/18 ,  A61B5/053 ,  G01R33/28 ,  A61M5/00 ,  A61B5/042 ,  A61B5/055 ,  A61B18/02 ,  A61M25/06 ,  A61B19/00 ,  A61M25/00 ,  A61M29/00 ,  A61M25/01 ,  A61M25/09

CPC classification number: A61B5/062 ,  A61B5/0044 ,  A61B5/042 ,  A61B5/0422 ,  A61B5/053 ,  A61B5/055 ,  A61B5/065 ,  A61B5/415 ,  A61B5/418 ,  A61B18/02 ,  A61B18/18 ,  A61B34/10 ,  A61B34/20 ,  A61B2090/365 ,  A61B2090/374 ,  A61B2090/3954 ,  A61M5/00 ,  A61M25/01 ,  A61M25/0127 ,  A61M29/00 ,  A61M2025/0089 ,  A61M2025/0166 ,  A61M2025/0681 ,  A61M2025/09175 ,  G01R33/286 ,  G01R33/287

Abstract: An MRI-compatible catheter that reduces localized heating due to MR scanner-induced currents includes an elongated flexible shaft having a distal end portion and an opposite proximal end portion. A handle is attached to the proximal end portion and includes an electrical connector interface configured to be in electrical communication with an MRI scanner. One or more RF tracking coils are positioned adjacent the distal end portion of the shaft. Each RF tracking coil includes a conductive lead, such as a coaxial cable, that extends between the RF tracking coil and the electrical connector interface and electrically connects the RF tracking coil to an MRI scanner. In some embodiments of the present invention, the conductive lead has a length sufficient to define an odd harmonic/multiple of a quarter wavelength of the operational frequency of the MRI Scanner, and/or includes a series of pre-formed back and forth segments along its length.

Abstract translation: 减少由于MR扫描器感应电流引起的局部加热的MRI兼容导管包括具有远端部分和相对近端部分的细长柔性轴。 手柄附接到近端部分并且包括被配置为与MRI扫描仪电连通的电连接器接口。 一个或多个RF跟踪线圈定位在轴的远端部分附近。 每个RF跟踪线圈包括在RF跟踪线圈和电连接器接口之间延伸的导电引线，例如同轴电缆，并将RF跟踪线圈电连接到MRI扫描器。 在本发明的一些实施例中，导电引线具有足以限定MRI扫描器的工作频率的四分之一波长的奇次谐波/倍数的长度，和/或包括一系列预先形成的前后段 它的长度。