-
公开(公告)号：US20230190930A1
公开(公告)日：2023-06-22
申请号：US17839029
申请日：2022-06-13
Applicant: MUSC Foundation for Research Development
Inventor： Daniel FERNANDES , Laura Schwartz , Natalie Sutkowski , Brian Hoel , Semyon Rubinchik
IPC: A61K39/395 , C07K16/18 , A61P35/00
CPC classification number: A61K39/395 , C07K16/18 , A61K39/3955 , A61P35/00 , C07K16/3015
Abstract: The present disclosure provides anti-nucleolin antibodies, methods of producing anti-nucleolin antibodies, and cells producing anti-nucleolin antibodies. Also provided are methods of using anti-nucleolin antibodies in treating malignant and non-malignant diseases.
-
Patent Agency Ranking
公开(公告)号：US11357849B2
公开(公告)日：2022-06-14
申请号：US16080720
申请日：2017-03-07
Inventor： Daniel Fernandes , Laura Schwartz , Natalie Sutkowski , Brian Hoel , Semyon Rubinchik
Abstract: The present disclosure provides anti-nucleolin antibodies, methods of producing anti-nucleolin antibodies, and cells producing anti-nucleolin antibodies. Also provided are methods of using anti-nucleolin antibodies in treating malignant and non-malignant diseases.
-
公开(公告)号：US10385128B2
公开(公告)日：2019-08-20
申请号：US14972698
申请日：2015-12-17
Applicant: MUSC Foundation for Research Development
Inventor： Natalie Sutkowski , Daniel Fernandes , Brian Hoel , Semyon Rubinchik
IPC: A61K39/395 , C07K16/28 , C07K16/18 , C07K16/30 , A61K47/68
Abstract: The present invention provides for methods of producing human monoclonal antibodies to human nucleolin, cells producing such antibodies, and the antibodies themselves. Also provided are methods of using the antibodies in diagnosing and treating malignant and non-malignant diseases wherein cells that express nucleolin on the cell surface contribute to the pathophysiology of the disease.
-
公开(公告)号：US20190382478A1
公开(公告)日：2019-12-19
申请号：US16454966
申请日：2019-06-27
Applicant: MUSC Foundation for Research Development
Inventor： Natalie Sutkowski , Daniel Fernandes , Brian Hoel , Semyon Rubinchik
Abstract: The present invention provides for methods of producing human monoclonal antibodies to human nucleolin, cells producing such antibodies, and the antibodies themselves. Also provided are methods of using the antibodies in diagnosing and treating malignant and non-malignant diseases wherein cells that express nucleolin on the cell surface contribute to the pathophysiology of the disease.
-
公开(公告)号：US20190194334A1
公开(公告)日：2019-06-27
申请号：US16080720
申请日：2017-03-07
Inventor： Daniel Fernandes , Laura Schwarts , Natalie Sutkowski , Brian Hoel , Semyon Rubinchik
CPC classification number: C07K16/2857 , A61K38/00 , A61K39/395 , A61K2039/505 , A61P35/00 , C07K16/18 , C07K16/28 , C07K16/3015 , C07K16/3061 , C07K2317/21 , C07K2317/56 , C07K2317/565 , C07K2317/73
Abstract: The present disclosure provides anti-nucleolin antibodies, methods of producing anti-nucleolin antibodies, and cells producing anti-nucleolin antibodies. Also provided are methods of using anti-nucleolin antibodies in treating malignant and non-malignant diseases.
-
公开(公告)号：US09709574B2
公开(公告)日：2017-07-18
申请号：US14205983
申请日：2014-03-12
Applicant: MUSC Foundation for Research Development
Inventor： Natalie Sutkowski , Semyon Rubinchik
IPC: C12N5/10 , C12N5/00 , C12N5/02 , G01N33/68 , C07K16/00 , C07K16/10 , C07K16/12 , C07K16/16 , C07K16/22 , C07K16/24 , C12N5/0781 , A61K39/00
CPC classification number: G01N33/6854 , A61K2039/505 , C07K16/00 , C07K16/1018 , C07K16/1271 , C07K16/16 , C07K16/22 , C07K16/244 , C07K2317/21 , C07K2317/75 , C07K2317/92 , C12N5/0635 , C12N2510/04 , Y02A50/407
Abstract: The present invention provides for methods of producing human monoclonal antibodies against a wide variety of antigens including bacterial and viral antigens, as well as tumor antigens, and various autoantigens. Also provided are the antibodies themselves, nucleic acids encoding such antibodies, cells producing such antibodies, and methods of using such antibodies for diagnostic assays and passive immunity against disease states such as infection and cancer.
-
-
-
-
-
Search Results
6
records
(took 0.029 seconds)
