公开(公告)号：US5235459A

公开(公告)日：1993-08-10

申请号：US883144

申请日：1992-05-14

Applicant: Manfred Meyer ,  Walter Geis

Inventor： Manfred Meyer ,  Walter Geis

IPC: G02B21/00 ,  G02B21/18 ,  G02B21/24

CPC classification number: G02B21/24 ,  G02B21/0088 ,  G02B21/18

Abstract: The invention is an inverted microscope with a housing having multiple integrated ray paths leading from the specimen being examined to (a) the viewer/operator and (b) one or more auxiliary ports used for image recording and/or measurement by accessories such as cameras and video recorders. The microscope lens is positioned below the specimen stage; and, positioned below the lens, is a simple reflector which deflects the combined rays from the lens diagonally upward toward the viewer at exactly the same angle at which the viewer looks into the microscope's binocular eyepieces. The position of this simple reflector is the lowest point in the unit's paths of rays, thereby significantly lowering the lens turret and, therefore, the specimen stage to a relatively low, ergonomically-appropriate position. The optical arrangement is simple and compact, minimizing the number of deflections in the path of the viewing rays. Further, light from the microscope lens is deflected along the second path to the auxiliary port and the recording camera by an optical element which is positioned above the reflector in the diagonally-upward path of rays, thereby providing ample room at the auxiliary port to permit use of a recording camera having an automatic-rewind housing. The invention also includes removable and interchangeable tubes which include viewing binoculars and/or an additional auxiliary image port positioned along a vertical path of rays and/or a further additional auxiliary image port positioned along a horizontal path of rays.

Abstract translation: 本发明是具有壳体的倒置显微镜，其具有从被检查样本引导的多个集成射线路径（a）观察者/操作者，以及（b）用于通过诸如照相机的附件进行图像记录和/或测量的一个或多个辅助端口 和录像机。 显微镜镜片位于样品台下方; 并且位于透镜下方的是一个简单的反射器，其将来自镜头的组合光线以相对于观察者看到显微镜的双目目镜的相同角度朝向观察者向观察者偏转。 这个简单的反射器的位置是单位光线路径中的最低点，从而显着降低了镜头转盘，因此将样品台显着降低到相对较低的符合人体工程学的适当位置。 光学布置简单紧凑，使观察光线的路径中的偏转次数最小化。 此外，来自显微镜镜片的光沿着第二路径偏转到辅助端口和记录照相机，该光学元件位于反射器上方的对角线向上的光线路径中，从而在辅助端口处提供足够的空间以允许 使用具有自动倒带外壳的记录照相机。 本发明还包括可移除和可互换的管，其包括观察双筒望远镜和/或沿着垂直的光线路径定位的附加辅助图像端口和/或沿着水平光线路径定位的另外的附加辅助图像端口。

公开(公告)号：US5138486A

公开(公告)日：1992-08-11

申请号：US614706

申请日：1990-11-16

Applicant: Manfred Meyer ,  Walter Geis

Inventor： Manfred Meyer ,  Walter Geis

IPC: G02B21/00 ,  G02B21/18

CPC classification number: G02B21/0088 ,  G02B21/18

Abstract: The invention is an inverted microscope with a housing having multiple integrated ray paths leading from the specimen being examined to (a) the viewer/operator and (b) one or more auxiliary ports used for image recording and/or measurement by accessories such as cameras and video recorders. The microscope lens is positioned below the specimen stage; and, positioned below the lens is a simple reflector which deflects the combined rays from the lens diagonally upward toward the viewer at exactly the same angle at which the viewer looks into the microscope's binocular eyepieces. The position of this simple reflector is the lowest point in the unit's paths of rays, thereby significantly lowering the lens turret and, therefore, the specimen stage to a relatively low, ergonomically-appropriate position. The optical arrangement is simple and compact, minimizing the number of deflections in the path of the viewing rays. Further, light from the microscope lens is deflected along the second path to the auxiliary port and the recording camera by an optical element which is positioned above the reflector in the diagonally-upward path of rays, thereby providing ample room at the auxiliary port to permit use of a recording camera having an automatic-rewind housing. The invention also includes removable and interchangeable tubes which include viewing binoculars and/or an additional auxiliary image port positioned along a vertical path of rays and/or a further additional auxiliary image port positioned along a horizontal path of rays.

Abstract translation: 本发明是具有壳体的倒置显微镜，其具有从被检查样本引导的多个集成射线路径（a）观察者/操作者，以及（b）用于通过诸如照相机的附件进行图像记录和/或测量的一个或多个辅助端口 和录像机。 显微镜镜片位于样品台下方; 并且位于透镜下方的是一个简单的反射器，其将来自镜头的组合光线沿着对角线向上朝向观察者偏转，其角度与观察者看到显微镜的双目目镜完全相同。 这个简单的反射器的位置是单位光线路径中的最低点，从而显着降低了镜头转盘，因此将样品台显着降低到相对较低的符合人体工程学的适当位置。 光学布置简单紧凑，使观察光线的路径中的偏转次数最小化。 此外，来自显微镜镜片的光沿着第二路径偏转到辅助端口和记录照相机，该光学元件位于反射器上方的对角线向上的光线路径中，从而在辅助端口处提供足够的空间以允许 使用具有自动倒带外壳的记录照相机。 本发明还包括可移除和可互换的管，其包括观察双筒望远镜和/或沿着垂直的光线路径定位的附加辅助图像端口和/或沿着水平光线路径定位的另外的附加辅助图像端口。

公开(公告)号：US5831764A

公开(公告)日：1998-11-03

申请号：US742062

申请日：1996-10-31

Applicant: Hans Brinkmann ,  Walter Geis

Inventor： Hans Brinkmann ,  Walter Geis

IPC: F16H55/28 ,  F16M11/18 ,  G02B21/26 ,  F16C19/00 ,  F16H27/02

CPC classification number: F16H55/28 ,  G02B21/26 ,  Y10T74/18808 ,  Y10T74/18848

Abstract: A drive system for the conversion of a rotary motion into a linear motion contains a belt drive similar to a block and pulley system, and a system of a rack and pinion that is driven synchronously with the belt drive. The pinion and the rack are adjusted with respect to each other such that the teeth of the pinion engage with relatively large play in the rack. When driving under normal load, the drive takes place without loading of the rack and pinion system by the belt drive, so that the reversal backlash and the play of the rack and pinion system remain without effect on the displacement motion. When an overloading of the moving part and a corresponding stretching of the drive belt occur, the tooth flanks of the pinion and of the rack are supported against each other and in this manner prevent tearing or overloading of the drive belt. The drive system has a high reproducibility and a small reversal back-lash, and is particularly applicable for the drive of the focusing motion in microscopes with automatic repositioning by means of a drive motor.

Abstract translation: 用于将旋转运动转换成直线运动的驱动系统包括类似于块和滑轮系统的带驱动器，以及与带驱动器同步地驱动的齿条和小齿轮的系统。 小齿轮和齿条相对于彼此调节，使得小齿轮的齿与齿条中的相对较大的间隙啮合。 当在正常负载下行驶时，传动是通过皮带传动装置进行齿条和小齿轮系统的装载而进行的，因此反转间隙和齿条与齿轮系统的运动保持不影响位移运动。 当发生运动部件的过载和相应的传动带的拉伸时，小齿轮和齿条的齿面彼此支撑并且以这种方式防止传动带的撕裂或过载。 驱动系统具有很高的再现性和小的反转间隙，特别适用于通过驱动电机自动重新定位的显微镜中的聚焦运动的驱动。

公开(公告)号：US6123459A

公开(公告)日：2000-09-26

申请号：US999780

申请日：1996-10-31

Applicant: Hans Brinkmann ,  Walter Geis

Inventor： Hans Brinkmann ,  Walter Geis

IPC: B23Q1/01 ,  B23Q1/58 ,  F16C29/04 ,  F16C33/61 ,  G02B21/24 ,  G02B21/26

CPC classification number: B23Q1/58 ,  B23Q1/017 ,  F16C29/04 ,  F16C29/041 ,  F16C33/61 ,  G02B21/24 ,  G02B21/241 ,  G02B21/26

Abstract: A linear guide includes rolling bodies that are inserted into mutually corresponding grooves of mutually guided parts. The guide surfaces for the rolling bodies are partially formed by plane surfaces of rotatable beveled round rods that are positioned in the grooves. The linear guide is constructed as a double guide on both sides with respectively two spaced-apart guide grooves on mutually opposed sides of the mutually guided parts. Because the guide surfaces are partially formed by the plane surfaces of the rotatable beveled round rods, wedge angles between the mutually guided parts are compensated. Manufacturing technical requirements regarding the matching of the distances of the guide grooves to each other are thereby greatly reduced.

Abstract translation: 线性引导件包括被插入相互引导部件的相互对应的槽中的滚动体。 用于滚动体的引导表面部分地由定位在凹槽中的可旋转的倾斜圆棒的平面表面形成。 线性引导件被构造为两侧的双引导件，并且在相互引导的部件的相对的相对侧上分别具有两个间隔开的引导槽。 由于导向表面部分地由可旋转的倒角圆棒的平面表面形成，所以相互引导的部分之间的楔角被补偿。 因此，引导槽的距离匹配的制造技术要求大大降低。

公开(公告)号：US4907158A

公开(公告)日：1990-03-06

申请号：US198294

申请日：1988-05-25

Applicant: Albrecht Kettler ,  Hubert Nasse ,  Walter Geis ,  Volker Wilke ,  Wilhelm Ansorge

Inventor： Albrecht Kettler ,  Hubert Nasse ,  Walter Geis ,  Volker Wilke ,  Wilhelm Ansorge

IPC: B25J7/00 ,  B25J9/00 ,  C12M1/00 ,  C12M1/26 ,  C12M3/00 ,  C12N5/02 ,  C12N15/89 ,  G01N33/48 ,  G02B21/32 ,  G02B21/36

CPC classification number: C12N15/89 ,  C12M35/00 ,  G02B21/32 ,  G02B21/365

Abstract: The invention is directed to a method for performing work on cells of a cell culture which includes microinjecting cells in the cell culture or drawing liquid from an individual cell or withdrawing whole cells with the aid of suction from the cell culture. The system is computer-supported and a marker movable in the image on a monitor is superposed on a television image of the cell culture. The marker is positioned in the television image on the cell to be injected by the operator by means of a relative movement of the marker with respect to the image. The coordinates of the cells marked in this way are stored by the computer which thereafter advances the capillary point automatically to the selected cells and penetrates the latter. Pursuant to a feature of an advantageous embodiment of the invention, the computer guides the penetration movement parallel to the longitudinal axis of the capillary by means of a superposed movement (k) of the object stage and through a superposed movement of the drive for the elevation displacement (z) of the capillary on the micromanipulator.

Abstract translation: 本发明涉及一种对细胞培养细胞进行工作的方法，该方法包括在细胞培养物中显微注射细胞或从单个细胞抽取液体或借助于来自细胞培养物的抽吸抽出全细胞。 该系统是计算机支持的，并且可以在监视器上的图像中移动的标记叠加在细胞培养物的电视图像上。 标记位于细胞上的电视图像中，以通过标记相对于图像的相对运动由操作者注射。 以这种方式标记的单元的坐标由计算机存储，然后计算机将毛细管点自动推进到所选择的单元并穿透其中。 根据本发明的有利实施例的特征，计算机借助于物体台的重叠运动（k）并通过用于高度的驱动器的叠加运动来引导平行于毛细管的纵向轴线的穿透运动 显微操纵器上毛细管的位移（z）。

公开(公告)号：US4330206A

公开(公告)日：1982-05-18

申请号：US117792

申请日：1980-02-01

Applicant: Hans Gausmann ,  Walter Geis

Inventor： Hans Gausmann ,  Walter Geis

IPC: G01N21/03 ,  G01N1/10

CPC classification number: G01N21/03 ,  G01N2021/0382 ,  G01N21/05

Abstract: The invention contemplates a cuvette or cell construction which is especially adapted to enable photometer or the like measurement of sample fluid admitted to the measurement chamber of the cell. The construction is applicable to fluid analysis under either the condition of a continuous-flow of specimen fluid, or under the condition that a single small sample has been vacuum-induced into the measurement chamber. The construction is inherently simple, is inherently self-clearing of air or gas bubbles in liquid samples, and provides inherently efficient cleansing of the measurement chamber when examined sample is withdrawn.

Abstract translation: 本发明考虑了一种比色皿或细胞结构，其特别适用于使得允许进入细胞测量室的样品流体的光度计等测量。 该结构适用于在样品流体连续流动的条件下或在单个小样品已被真空诱导到测量室中的条件下的流体分析。 该结构本质上是简单的，本质上是液体样品中空气或气泡的自清除，并且当检测样品被取出时，提供测量室的固有效率的清洁。