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    Apparatus and method incorporating an ultrasound transducer onto a delivery member
    6.
    发明授权
    Apparatus and method incorporating an ultrasound transducer onto a delivery member 有权
    将超声换能器并入到输送部件上的装置和方法

    公开(公告)号：US06607502B1

    公开(公告)日：2003-08-19

    申请号：US09435280

    申请日：1999-11-05

    申请人： Mark A. Maguire ,  James C. Peacock, III

    发明人： Mark A. Maguire ,  James C. Peacock, III

    IPC分类号： A61B1720

    CPC分类号： A61N7/02 ,  A61B17/2202 ,  A61B2017/00243 ,  A61B2017/22051 ,  A61B2017/22062 ,  A61B2017/22069 ,  A61B2017/320072 ,  A61B2017/320088 ,  B06B1/0625

    摘要： A medical device assembly and method provides an ultrasound transducer mounted onto a delivery member, such the elongate body of a catheter shaft, without a support structure bridging between a separation area between the transducer and the shaft. Mounting flanges are extend from either end of the transducer and are mounted at first and second locations along the catheter shaft such that the transducer is suspended over the catheter shaft between those mounting locations. The flanges may be connected by an intermediate member, with the transducer supported on either an outer surface or an inner surface of the intermediate member. The intermediate member may also provide a housing with an enclosed space that houses the transducer, wherein the flanges extend from the housing for mounting to the catheter shaft. In an overall tissue coupling system, a cylindrical ultrasound transducer are mounted onto a catheter shaft by use of such mounting flanges extending from the transducer's ends and such that the ultrasound transducer is enclosed within a balloon also provided on the catheter. The balloon is ideally adapted to engage a circumferential region of tissue where a pulmonary vein extends from an atrium such that the cylindrical ultrasound transducer is able to couple through the balloon inflation fluid and to the circumferential region of tissue surrounding the balloon for ablation. The transducer is substantially “airbacked” when mounted onto a delivery member according to the present assembly and method.

    摘要翻译： 医疗装置组件和方法提供了安装在输送构件（例如导管轴的细长主体）上的超声换能器，而不需要在换能器和轴之间的分离区域之间桥接的支撑结构。 安装法兰从换能器的任一端延伸并沿着导管轴安装在第一和第二位置处，使得换能器悬挂在导管轴之间的这些安装位置之间。 凸缘可以由中间构件连接，换能器支撑在中间构件的外表面或内表面上。 中间构件还可以提供具有容纳换能器的封闭空间的壳体，其中凸缘从壳体延伸以用于安装到导管轴。 在整体组织连接系统中，通过使用从换能器端部延伸的这种安装凸缘将圆柱形超声换能器安装到导管轴上，并且使得超声换能器被包围在也设置在导管上的球囊内。 气球理想地适于接合肺静脉从心房延伸的组织的圆周区域，使得圆柱形超声换能器能够耦合穿过球囊充气流体并且耦合到围绕球囊的组织的周边区域以进行消融。 当根据本组件和方法将传感器安装到传送部件上时，传感器基本上被“空背”。

    Circumferential ablation device assembly and methods of use and manufacture providing an ablative circumferential band along an expandable member
    9.
    发明授权
    Circumferential ablation device assembly and methods of use and manufacture providing an ablative circumferential band along an expandable member 有权

    公开(公告)号：US06500174B1

    公开(公告)日：2002-12-31

    申请号：US09435283

    申请日：1999-11-05

    申请人： Mark A. Maguire ,  James C. Peacock, III

    发明人： Mark A. Maguire ,  James C. Peacock, III

    IPC分类号： A61B1818

    CPC分类号： A61B18/1492 ,  A61B2017/00243 ,  A61B2017/00256 ,  A61B2017/00318 ,  A61B2018/00023 ,  A61B2018/00065 ,  A61B2018/00136 ,  A61B2018/00214 ,  A61B2018/00238 ,  A61B2018/00369 ,  A61B2018/00815 ,  A61B2018/00821 ,  A61B2018/044 ,  A61B2090/3966 ,  A61N7/02 ,  Y10T29/49169 ,  Y10T29/49888 ,  Y10T29/49982

    摘要： A medical balloon catheter assembly includes a balloon having a permeable region and a non-permeable region. The balloon is constructed at least in part from a fluid permeable tube such that the permeable region is formed from a porous material which allows a volume of pressurized fluid to pass from within a chamber formed by the balloon and into the permeable region sufficiently such that the fluid may be ablatively coupled to tissue engaged by the permeable region. The non-permeable region is adapted to substantially block the pressurized fluid from passing from within the chamber and outwardly from the balloon. The porous material may be a porous fluoropolymer, such as porous polytetrafluoroethylene, and the pores may be created by voids which are inherently formed between an interlocking node-fibril network which makes up the fluoropolymer. Such voids may be created according to one mode by expanding the fluoropolymer. The balloon may be formed such that the porous material extends along both the permeable and non-permeable regions. In one mode of this construction, the porous material is porous along the permeable region but is non-porous along the non-permeable region, such as for example by expanding only the permeable region in order to render sufficient voids in the node-fibril network to provide permeable pores in that section. The voids or pores in the porous material may also be provided along both permeable and non-permeable sections but are substantially blocked with an insulator material along the non-permeable section in order to prevent fluid from passing therethrough. The insulator material may be dip coated, deposited, or extruded with the porous material in order to fill the voids. The insulator material may in one mode be provided along the entire working length of the balloon and then selectively removed along the permeable section, or may be selectively exposed to only the non-permeable sections in order to fill the voids or pores there.

    Method for ablation of heart tissue
    10.
    发明授权
    Method for ablation of heart tissue 有权
    心脏组织消融方法

    公开(公告)号：US6156034A

    公开(公告)日：2000-12-05

    申请号：US218769

    申请日：1998-12-22

    申请人： Francisco G. Cosio ,  Frank Nguyen ,  Mark A. Maguire

    发明人： Francisco G. Cosio ,  Frank Nguyen ,  Mark A. Maguire

    IPC分类号： A61B18/14 ,  A61M25/00 ,  A61M25/01 ,  A61B5/042

    CPC分类号： A61M25/0141 ,  A61M25/0144 ,  A61M25/0147 ,  A61B18/14 ,  A61B2018/00946 ,  A61B2018/00952 ,  A61M2025/015 ,  A61M2025/0161 ,  A61M25/0054

    摘要： A dual curve ablation catheter (2), especially suited for treating atrial flutter, includes a shaft (4) with a deflectable tip (20) at the distal end (6) and a handle (10) at the proximal end (8). The tip includes a highly flexible distal segment (30), a relatively stiff intermediate segment (28) and a flexible proximal segment (26) so that pulling on a manipulator wire (16) attached to the distal segment causes the distal segment to curve and engage, for example, an isthmus of tissue (106) adjacent the tricuspid valve (104) and the inferior vena cava (98) and causes the proximal segment to curve and press against the wall (110) of the inferior vena cava so to stabilize the catheter. Ablation energy can be supplied through the ablation electrodes (48, 68) simultaneously or one at a time to ablate tissue at the isthmus without the need for moving the catheter.

    摘要翻译： 特别适用于治疗心房扑动的双曲线消融导管（2）包括在远端（6）处具有可偏转尖端（20）的轴（4）和在近端（8）处的手柄（10）。 尖端包括高度柔性的远侧段（30），相对刚性的中间段（28）和柔性近端段（26），使得牵引附接到远端段的操纵杆（16）导致远端段弯曲，并且 接合例如邻近三尖瓣（104）和下腔静脉（98）的组织（106）的峡部，并使近端段弯曲并压靠下腔静脉的壁（110）以便稳定 导管。 可以同时或一次一次地通过消融电极（51,68）提供消融能量以在峡部上烧蚀组织，而不需要移动导管。