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公开(公告)号：US08449898B2
公开(公告)日：2013-05-28
申请号：US12679361
申请日：2008-10-23
IPC分类号： A01N43/40 , A01N43/78 , A01N43/80 , A01N43/56 , A01N43/653 , A01N43/90 , A01P3/00 , C07D211/00 , C07D239/00
CPC分类号： A01N43/90 , A01N43/40 , A01N43/56 , A01N43/653 , A01N43/78 , A01N43/80 , C07D413/14 , C07D417/14 , A01N37/34 , A01N37/36 , A01N37/46 , A01N37/50 , A01N43/42 , A01N43/50 , A01N43/54 , A01N43/76 , A01N47/04 , A01N47/12 , A01N47/14 , A01N47/24 , A01N47/34 , A01N57/12 , A01N59/20 , A01N2300/00
摘要： Disclosed is a fungicidal composition comprising (a) at least one compound selected from the compounds of Formula 1 N-oxides, and salts thereof, wherein R1, R2, A, G, W, Z1, X, J, and n are as defined in the disclosure, and (b) at least one additional fungicidal compound. Also disclosed is a method for controlling plant diseases caused by fungal plant pathogens comprising applying to the plant or portion thereof, or to the plant seed, a fungicidally effective amount of the aforesaid composition.Also disclosed is a composition comprising component (a) of aforesaid composition and at least one insecticide.Also disclosed are compounds of Formula 1A, 1B and 1C, wherein R1, R2, A, G, W, Z1, X, J, n, Z3, M and J1 are as defined in the disclosure.
摘要翻译： 公开了一种杀真菌组合物，其包含（a）至少一种选自式1化合物的化合物及其盐的化合物，其中R 1，R 2，A，G，W，Z 1，X，J和n如上定义 在本公开中，和（b）至少一种另外的杀真菌化合物。 还公开了一种控制由真菌植物病原体引起的植物病害的方法，包括向植物或其部分或植物种子施用杀真菌有效量的上述组合物。 还公开了包含上述组合物的组分（a）和至少一种杀虫剂的组合物。 还公开了式1A，1B和1C的化合物，其中R1，R2，A，G，W，Z1，X，J，n，Z3，M和J1如本公开中所定义。
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公开(公告)号：US08349870B2
公开(公告)日：2013-01-08
申请号：US12863875
申请日：2009-01-22
IPC分类号： A61K31/445 , C07D405/00
CPC分类号： C07D417/04 , C07D417/14
摘要： Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof, wherein E, R2, G, Z1, J and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling plant disease caused by a fungal pathogen comprising applying an effective amount of a compound or a composition of the invention.
摘要翻译： 公开了式1的化合物，包括所有几何和立体异构体，N-氧化物及其盐，其中E，R 2，G，Z 1，J和n如本公开所定义。 还公开了含有式1化合物的组合物和用于控制由真菌病原体引起的植物病害的方法，包括施用有效量的本发明化合物或组合物。
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公开(公告)号：US20100292275A1
公开(公告)日：2010-11-18
申请号：US12863875
申请日：2009-01-22
IPC分类号： A01N43/80 , C07D417/14 , A01P3/00
CPC分类号： C07D417/04 , C07D417/14
摘要： Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof, wherein E, R2, G, Z1, J and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling plant disease caused by a fungal pathogen comprising applying an effective amount of a compound or a composition of the invention.
摘要翻译： 公开了式1的化合物，包括所有几何和立体异构体，N-氧化物及其盐，其中E，R 2，G，Z 1，J和n如本公开所定义。 还公开了含有式1化合物的组合物和用于控制由真菌病原体引起的植物病害的方法，包括施用有效量的本发明化合物或组合物。
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公开(公告)号：US08642634B2
公开(公告)日：2014-02-04
申请号：US12303256
申请日：2007-07-27
IPC分类号： A61K31/422 , A61K31/427 , C07D263/10 , C07D277/10
CPC分类号： C07D495/10 , C07D211/62 , C07D263/14 , C07D401/06 , C07D401/14 , C07D413/04 , C07D417/04 , C07D417/14 , C07D498/10
摘要： Disclosed are compounds of Formulae 1, 1A, 1B and 1C including all geometric and stereoisomers, N-oxides, and salts thereof, wherein R1, R2, R4a1, R4a2, A, Aa, G, M, W, Z1, Z3, X, J, J1 and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling plant disease caused by a fungal pathogen comprising applying an effective amount of a compound or a composition of the invention.
摘要翻译： 公开了具有所有几何和立体异构体，N-氧化物及其盐的式1A，1B和1C的化合物，其中R1，R2，R4a1，R4a2，A，Aa，G，M，W，Z1，Z3，X ，J，J1和n如本公开中所定义。 还公开了含有式1化合物的组合物和用于控制由真菌病原体引起的植物病害的方法，包括施用有效量的本发明化合物或组合物。
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公开(公告)号：US20130030002A1
公开(公告)日：2013-01-31
申请号：US13640092
申请日：2011-04-15
IPC分类号： A01N43/78 , C07D417/06 , A01N43/40 , C07D417/14 , A01N43/58 , A01P3/00 , C07D401/06 , A01N43/56 , C07D277/30 , A01N43/54
CPC分类号： C07D417/04 , C07D403/14 , C07D407/14 , C07D409/14 , C07D413/14 , C07D417/14
摘要： Disclosed are compounds of Formula 1, including all stereoisomers, N-oxides, and salts thereof, wherein E, X, G, W2 and Z are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling plant disease caused by a fungal pathogen comprising applying an effective amount of a compound or a composition of the invention.Also disclosed are compounds of Formula 1A including all stereoisomers, N-oxides, and salts thereof, wherein E, X, G and Z1 are as defined in the disclosure. Also disclosed is the use of the compounds of Formula 1A as intermediates for preparing compounds of Formula 1.
摘要翻译： 公开了式1的化合物，包括所有立体异构体，N-氧化物及其盐，其中E，X，G，W 2和Z如本公开所定义。 还公开了含有式1化合物的组合物和用于控制由真菌病原体引起的植物病害的方法，包括施用有效量的本发明化合物或组合物。 还公开了包括所有立体异构体，N-氧化物及其盐的式1A化合物，其中E，X，G和Z1如本公开所定义。 还公开了式1A化合物作为制备式1化合物的中间体的用途。
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公开(公告)号：US20120034315A1
公开(公告)日：2012-02-09
申请号：US13265138
申请日：2010-04-19
IPC分类号： A01N59/20 , A61K31/454 , A01N43/90 , A01N43/54 , A01P7/04 , A01N57/12 , A01N57/10 , A01N43/42 , A01P3/00 , C07D417/14 , A01N55/10
CPC分类号： C07D417/14 , A01N43/653 , A01N43/80 , A01N43/84 , A01N57/12 , A01N59/20
摘要： Disclosed are solid forms of 1-[4-[4-[5-(2,6-difluorophenyl)-4,5-dihydro-3-isoxazolyl]-2-thiazolyl]-1-piperidinyl]-2-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]ethanone (Compound 1). Methods for the preparation of solid forms of Compound 1 and for the conversion of one solid form of Compound 1 into another are disclosed.Disclosed are fungicidal compositions comprising a fungicidally effective amount of a solid form of Compound 1 and at least one additional component selected from the group consisting of surfactants, solid diluents and liquid carriers. Compositions comprising a mixture of a solid form of Compound 1 and at least one other fungicide or insecticide are also disclosed.Also disclosed are methods for controlling plant diseases caused by fungal plant pathogens comprising applying to a plant or portion thereof, or to a plant seed, a fungicidally effective amount of a solid form of Compound 1.
摘要翻译： 公开了1- [4- [4- [5-（2,6-二氟苯基）-4,5-二氢-3-异恶唑基] -2-噻唑基] -1-哌啶基] -2- [5- （三氟甲基）-1H-吡唑-1-基]乙酮（化合物1）。 公开了制备化合物1的固体形式和将一种固体形式的化合物1转化成另一种的方法。 公开了包含杀真菌有效量的固体形式的化合物1和至少一种选自表面活性剂，固体稀释剂和液体载体的另外的组分的杀真菌组合物。 还公开了包含固体形式的化合物1和至少一种其它杀真菌剂或杀虫剂的混合物的组合物。 还公开了用于控制由真菌植物病原体引起的植物疾病的方法，包括向植物或其部分或植物种子施用杀真菌有效量的化合物1的固体形式。
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公开(公告)号：US20100286147A1
公开(公告)日：2010-11-11
申请号：US12811126
申请日：2009-01-22
IPC分类号： A61K31/5377 , A61K31/497 , A61K31/454 , C07D417/14
CPC分类号： C07D417/14 , C07D417/04
摘要： Disclosed are compounds of Formulae 1 and 1A (including all geometric and stereoisomers), N-oxides, and salts thereof, wherein R1, R2, A, G, M, W, Z1, X, J, J1 and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling plant disease caused by a fungal pathogen comprising applying an effective amount of a compound or a composition of the invention.
摘要翻译： 公开了式1和1A的化合物（包括所有几何和立体异构体），N-氧化物及其盐，其中R1，R2，A，G，M，W，Z1，X，J，J1和n如 披露。 还公开了含有式1化合物的组合物和用于控制由真菌病原体引起的植物病害的方法，包括施用有效量的本发明化合物或组合物。
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公开(公告)号：US20090156592A1
公开(公告)日：2009-06-18
申请号：US12303256
申请日：2007-07-27
IPC分类号： A01N43/80 , C07D417/14 , C07D231/12 , C07D231/16 , C07D401/14 , A01P3/00 , A01N43/78 , C07D413/00 , C07D413/14 , A01N43/84
CPC分类号： C07D495/10 , C07D211/62 , C07D263/14 , C07D401/06 , C07D401/14 , C07D413/04 , C07D417/04 , C07D417/14 , C07D498/10
摘要： Disclosed are compounds of Formulae 1, 1A, 1B and 1C including all geometric and stereoisomers, N-oxides, and salts thereof, wherein R1, R2, R4a1, R4a2, A, Aa, G, M, W, Z1, Z3, X, J, J1 and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling plant disease caused by a fungal pathogen comprising applying an effective amount of a compound or a composition of the invention.
摘要翻译： 公开了具有所有几何和立体异构体，N-氧化物及其盐的式1A，1B和1C的化合物，其中R1，R2，R4a1，R4a2，A，Aa，G，M，W，Z1，Z3，X ，J，J1和n如本公开中所定义。 还公开了含有式1化合物的组合物和用于控制由真菌病原体引起的植物病害的方法，包括施用有效量的本发明化合物或组合物。
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公开(公告)号：US20130261154A1
公开(公告)日：2013-10-03
申请号：US13990542
申请日：2011-12-12
申请人： Mary Ann Hanagan , Gilles Seburyamo
发明人： Mary Ann Hanagan , Gilles Seburyamo
IPC分类号： A01N43/80 , C07D417/14
CPC分类号： A01N43/80 , A01N43/78 , C07D417/14
摘要： Disclosed are compounds of Formula 1, including all stereoisomers, N-oxides, and salts thereof, wherein E, X, G, J, Z, and Q are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling plant disease caused by a fungal pathogen comprising applying an effective amount of a compound or a composition of the invention.
摘要翻译： 公开了式1的化合物，包括所有立体异构体，N-氧化物及其盐，其中E，X，G，J，Z和Q如本公开所定义。 还公开了含有式1化合物的组合物和用于控制由真菌病原体引起的植物病害的方法，包括施用有效量的本发明化合物或组合物。
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公开(公告)号：US20110045101A1
公开(公告)日：2011-02-24
申请号：US12988888
申请日：2009-05-07
申请人： Thomas Paul Selby , James Francis Bereznak , John Joseph Bisaha , Amy X. Ding , Mary Ann Hanagan , Jeffrey Keith Long , Andrew Edmund Taggi , Vijayagopal Gopalsamuthiram
发明人： Thomas Paul Selby , James Francis Bereznak , John Joseph Bisaha , Amy X. Ding , Mary Ann Hanagan , Jeffrey Keith Long , Andrew Edmund Taggi , Vijayagopal Gopalsamuthiram
IPC分类号： A01N59/20 , C07D233/68 , A01N43/50 , A01P3/00 , C07D233/64 , C07D401/04 , C07D403/04 , A01N43/78 , C07D417/04 , A01N43/56 , C07D231/12 , C07D231/20 , A01N43/647 , C07D249/04 , A01N43/828 , A01N43/653 , A01N43/66 , A01N43/54 , A01N43/88
CPC分类号： C07D233/68 , A01N43/50 , A01N43/78 , C07D231/12 , C07D231/16 , C07D231/20 , C07D233/64 , C07D233/90 , C07D249/06 , C07D401/04
摘要： Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof, wherein J is Q2 or R1; X is N, CR2 or CQ3; Y is N or CR3; Z is N or CR4; and Q1, Q2, Q3, R1 R2 and R3 are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling plant disease caused by a fungal pathogen comprising applying an effective amount of a compound or a composition of the invention.
摘要翻译： 公开了式1的化合物，包括所有几何和立体异构体的N-氧化物及其盐，其中J是Q2或R1; X为N，CR2或CQ3; Y为N或CR 3; Z是N或CR4; 并且Q1，Q2，Q3，R1R2和R3如本公开中所定义。 还公开了含有式1化合物的组合物和用于控制由真菌病原体引起的植物病害的方法，包括施用有效量的本发明化合物或组合物。
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