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    Transcatheter delivery system and method with controlled expansion and contraction of prosthetic heart valve
    1.
    发明授权
    Transcatheter delivery system and method with controlled expansion and contraction of prosthetic heart valve 有权

    公开(公告)号：US11020223B2

    公开(公告)日：2021-06-01

    申请号：US15387071

    申请日：2016-12-21

    Applicant: Medtronic, Inc.

    Inventor： Matthew Rust ,  Savage Padraig ,  Gianfranco Pellegrini ,  Finn Rinne

    IPC: A61F2/24 ,  A61F2/95 ,  A61F2/966

    Abstract: A delivery system for use with a prosthetic heart valve having a stent frame to which a valve structure is attached, includes a shaft assembly including a distal end and a coupling structure disposed near the distal end and configured to be coupled to a distal end of the prosthetic heart valve. The system includes a sheath assembly defining a lumen sized to slidably receive the shaft assembly. The delivery system is configured to transition from a loaded state in which the sheath assembly encompasses the prosthetic heart valve to a deployed state in which the sheath assembly is withdrawn from the prosthetic heart valve. The coupling structure is configured to provide a controlled expansion or contraction of the distal end of the prosthetic heart valve based on longitudinal movement of the distal end of the shaft assembly.

    Stents for prosthetic heart valves
    2.
    发明授权
    Stents for prosthetic heart valves 有权

    公开(公告)号：US10231832B2

    公开(公告)日：2019-03-19

    申请号：US15482032

    申请日：2017-04-07

    Applicant: Medtronic, Inc.

    Inventor： Padraig Savage ,  Gianfranco Pellegrini ,  Finn Rinne ,  Matthew Rust ,  Michael Krivoruchko

    IPC: A61F2/24

    Abstract: A stented valve including a stent structure having a generally tubular body portion, an interior area, a longitudinal axis, an first end, an second end, and an outer surface; at least one outflow barb extending from the outer surface of the stent adjacent to the first end of the stent structure and toward the second end of the stent structure; at least one inflow barb extending from the outer surface of the stent adjacent to the second end of the stent structure and toward the first end of the stent structure; and a valve structure attached within the interior area of the stent structure.

    Anti-paravalvular leakage component for a transcatheter valve prosthesis
    3.
    发明授权
    Anti-paravalvular leakage component for a transcatheter valve prosthesis 有权
    用于经导管瓣膜假体的抗瓣膜泄漏组件

    公开(公告)号：US08986375B2

    公开(公告)日：2015-03-24

    申请号：US13795066

    申请日：2013-03-12

    Applicant: Medtronic, Inc.

    Inventor： Kshitija Garde ,  Philip Haarstad ,  Igor Kovalsky ,  Stephen Nash ,  Gianfranco Pellegrini ,  Finn Rinne ,  Matthew Rust ,  Jeffrey Sandstrom ,  Padraig Savage ,  William Steinberg

    IPC: A61F2/24

    CPC classification number: A61F2/2445 ,  A61F2/2403 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2250/0069

    Abstract: A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the stent which includes a plurality of self-expanding struts and an annular sealing membrane. Each strut has a first end coupled to a distal end of the stent and a second end not coupled to the stent. Each anti-paravalvular leakage component is moveable between a compressed configuration and a deployed configuration. In the compressed configuration, each strut extends distally away from the distal end of the stent. In the deployed configuration, each strut extends proximally away from the distal end of the stent. In an embodiment hereof, the deployed strut has a C-shape and is twisted such that the C-shape lies in a plane substantially along or tangential with the outer surface of the stent. In another embodiment hereof, the deployed strut is rolled-up and extends radially away from the outer surface of the stent.

    Abstract translation: 经导管瓣膜假体包括可扩张的管状支架，支架内的假体瓣膜，以及耦合到环绕支架并包围多个自膨胀支柱和环形密封膜的抗瓣膜泄漏部件。 每个支柱具有联接到支架的远端的第一端和未联接到支架的第二端。 每个反paravalvular泄漏组件可在压缩配置和部署配置之间移动。 在压缩构型中，每个支柱远离支架远端延伸。 在展开的构造中，每个支柱向近端延伸远离支架的远端。 在本发明的一个实施例中，所展开的支柱具有C形并且被扭曲，使得C形位于与支架的外表面基本上沿或相切的平面中。 在本发明的另一个实施例中，部署的支柱被卷起并且从支架的外表面径向延伸。

    Transcatheter prosthetic heart valve delivery system with funnel recapturing feature and method
    4.
    发明授权
    Transcatheter prosthetic heart valve delivery system with funnel recapturing feature and method 有权
    经导管假体心脏瓣膜输送系统，具有漏斗回收特征和方法

    公开(公告)号：US08986372B2

    公开(公告)日：2015-03-24

    申请号：US13969784

    申请日：2013-08-19

    Applicant: Medtronic, Inc.

    Inventor： Robert Murry, III ,  Susheel Deshmukh ,  Padraig Savage ,  Matthew Rust

    IPC: A61F2/24 ,  A61F2/95

    CPC classification number: A61F2/2436 ,  A61F2002/9517 ,  A61F2002/9534

    Abstract: A delivery device for percutaneously deploying a stented prosthetic heart valve. The device includes a delivery capsule and a recapture sheath. The capsule is configured to compressively retain the prosthesis. The recapture sheath includes a funnel segment having a plurality of circumferentially spaced runners and a polymer overlay. The runners are attached to a shaft and terminate at a distal tip. The overlay surrounds the runners, and is bonded to the shaft but not to at least the tips. The funnel segment is transitionable from a normal condition to an expanded condition forming a funnel shape with a distally increasing diameter, and self-transitionable back toward the normal condition. The funnel segment facilitates sliding of the capsule over a partially deployed region of the prosthesis as part of a recapturing operation. The runners provide columnar strength, with the overlay controlling a shape of the funnel segment.

    Abstract translation: 用于经皮部署支架假体心脏瓣膜的输送装置。 该装置包括递送胶囊和再捕获护套。 胶囊被构造成压缩地保持假体。 重新捕获鞘包括具有多个周向间隔的流道和聚合物覆盖层的漏斗段。 流道附着在轴上，并终止于远端。 覆盖物围绕流道，并且结合到轴，但至少不是尖端。 漏斗段可以从正常状态转变成扩展状态，形成具有向远端增加的直径的漏斗形状，并且可自由转变回正常状态。 漏斗段有助于将胶囊滑动在假体的部分展开的区域上，作为重新捕获操作的一部分。 跑步者提供柱状强度，覆盖层控制漏斗段的形状。

    PROSTHETIC VALVES AND ASSOCIATED APPARTUSES, SYSTEMS AND METHODS
    8.
    发明申请
    PROSTHETIC VALVES AND ASSOCIATED APPARTUSES, SYSTEMS AND METHODS 审中-公开
    前置阀和相关配件，系统和方法

    公开(公告)号：US20160287384A1

    公开(公告)日：2016-10-06

    申请号：US15162909

    申请日：2016-05-24

    Applicant: Medtronic, Inc.

    Inventor： Michael Gloss ,  Timothy Groen ,  Carolyn Majkrzak ,  Matthew Rust ,  Timothy Ryan ,  Matthew Weston

    IPC: A61F2/24 ,  A61F2/07

    CPC classification number: A61F2/2418 ,  A61F2/07 ,  A61F2/24 ,  A61F2/2409 ,  A61F2/2469 ,  A61F2/82 ,  A61F2220/0075 ,  A61F2230/0069 ,  A61F2250/0039

    Abstract: A valve prosthesis includes an expandable frame comprising an outflow portion and an inflow portion connected to the outflow portion. The frame defines a central lumen extending between the outflow portion and the inflow portion. The frame is generally cylindrical in a fully expanded configuration. When the frame is in the fully expanded configuration, an outer surface of the inflow portion is concave. The inflow portion has an upper inflow portion and a lower inflow portion. When the frame is in the fully expanded configuration, the upper inflow portion flares outwardly from the central lumen of the frame to greater extent than the lower inflow portion.

    Abstract translation: 瓣膜假体包括可扩张框架，其包括流出部分和连接到流出部分的流入部分。 框架限定在流出部分和流入部分之间延伸的中心腔。 框架通常为圆柱形，处于完全展开的构型。 当框架处于完全展开的构型时，流入部分的外表面是凹的。 流入部具有上流入部和下流入部。 当框架处于完全展开的构造时，上流入部分从框架的中央腔向外扩展到比下流入部分更大的程度。

    STENTS FOR PROSTHETIC HEART VALVES
    9.
    发明申请
    STENTS FOR PROSTHETIC HEART VALVES 有权

    公开(公告)号：US20210077256A1

    公开(公告)日：2021-03-18

    申请号：US17086511

    申请日：2020-11-02

    Applicant: Medtronic, Inc.

    Inventor： Gianfranco M. Pellegrini ,  Mike Krivoruchko ,  Finn Rinne ,  Matthew Rust

    IPC: A61F2/24

    Abstract: A prosthetic valve including a wire frame having a generally tubular body portion, an interior area, a longitudinal axis, a first end comprising a plurality of crowns, and a second end comprising a greater number of crowns than the first end. The wire frame includes a plurality of adjacent rows of modified diamond-shaped structures extending between the first and second ends. The prosthetic valve further includes a valve structure that includes a plurality of leaflets and that is attached within the interior area of the wire frame.

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