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公开(公告)号：US20210330234A1
公开(公告)日：2021-10-28
申请号：US17366397
申请日：2021-07-02
Applicant: Medtronic, Inc.
Inventor： Dwight E. Nelson , Jianping Wu , Rahul Gupta , Yan Zhao
Abstract: In some examples, a processor determines a patient state based on activity of a bioelectrical brain signal of a patient in one or more frequency sub-bands of a frequency band of interest. For example, a processor may determine a patient state based on the power level of a bioelectrical brain signal of the patient in one or more frequency sub-bands of a frequency band, or based on a spectral pattern of a bioelectrical brain signal in a frequency band, such as a shift in a power distribution between sub-bands, a change in the peak frequency within one or more sub-bands, a pattern of the power distribution over one or more frequency sub-bands, or a width or a variability of one or more sub-bands exhibiting a relatively high or low level of activity.
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2.发明申请Method and Apparatus for Event-Triggered Reinforcement of a Favorable Brain State 有权用于事件触发加强有利脑部状态的方法和装置公开(公告)号：US20130245714A1
公开(公告)日：2013-09-19
申请号：US13892401
申请日：2013-05-13
Applicant: Medtronic, Inc.
Inventor： Rahul Gupta , Gabriela C. Molnar , Dwight E. Nelson
IPC: A61N1/36
CPC classification number: A61N1/3606 , A61B5/4064 , A61B5/4082 , A61B5/4094 , A61B5/6868 , A61N1/0529 , A61N1/36025 , A61N1/36064 , A61N1/36067 , A61N1/36071 , A61N1/36082 , A61N1/36139 , A61N1/36167
Abstract: Methods and apparatuses are disclosed for potentiating a favorable brain state that is associated with relief in symptoms of a brain condition. Techniques include monitoring one or more brain signals and detecting an episode of a favorable brain state based on the one or more brain signals, the favorable brain state associated with a decrease in one or more symptoms of a brain condition of the patient. Then, in response to the detection of the favorable brain state episode, electrical stimulation that potentiates the favorable brain state is delivered to the brain of the patient, the electrical stimulation delivered within a window of time opened for detection of each favorable brain state episode.
Abstract translation: 公开了用于增强与大脑状况症状缓解相关的有利的脑状态的方法和装置。 技术包括基于一个或多个脑信号监测一个或多个脑信号和检测有利的脑状态的发作，所述脑信号与患者的脑部状况的一个或多个症状的减少有关的有利的脑状态。 然后，响应于有利的脑状态发作的检测，将有利的脑状态的电刺激递送到患者的大脑，在打开每个有利的脑状态发作的时间窗口内递送电刺激。
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公开(公告)号：US20210369169A1
公开(公告)日：2021-12-02
申请号：US17394355
申请日：2021-08-04
Applicant: Medtronic, Inc.
Inventor： Dwight E. Nelson , Jianping Wu , Rahul Gupta , Yan Zhao
Abstract: In some examples, a processor determines a patient state based on activity of a bioelectrical brain signal of a patient in one or more frequency sub-bands of a frequency band of interest. For example, a processor may determine a patient state based on the power level of a bioelectrical brain signal of the patient in one or more frequency sub-bands of a frequency band, or based on a spectral pattern of a bioelectrical brain signal in a frequency band, such as a shift in a power distribution between sub-bands, a change in the peak frequency within one or more sub-bands, a pattern of the power distribution over one or more frequency sub-bands, or a width or a variability of one or more sub-bands exhibiting a relatively high or low level of activity.
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公开(公告)号：US20150306391A1
公开(公告)日：2015-10-29
申请号：US14685690
申请日：2015-04-14
Applicant: Medtronic, Inc.
Inventor： Jianping Wu , Rahul Gupta , Dwight E. Nelson
IPC: A61N1/36
CPC classification number: A61N1/36078 , A61B5/048 , A61B5/4809 , A61B5/4812 , A61B5/4836 , A61N1/0534 , A61N1/36132 , A61N1/36139 , A61N1/36167
Abstract: In some examples, a medical device delivers electrical stimulation to the external portion of the globus pallidus of a brain of a patient in order to treat a sleep impairment of the patient. In some examples, the electrical stimulation may be delivered via one or more electrodes implanted in the GPe of the brain. In some examples, an electrical stimulation device is configured to deliver electrical stimulation therapy to the GPe based on detection of a sleep state of a patient. The sleep state may include, for example, a state in which the patient is awake and intending on sleeping, is awake and attempting to sleep or has initiated sleep. In addition, in some examples, an electrical stimulation device is configured to deliver electrical stimulation therapy to the GPe based on detection of an awake state of a patient.
Abstract translation: 在一些示例中，医疗装置向患者脑部的苍白球外部递送电刺激，以便治疗患者的睡眠障碍。 在一些示例中，电刺激可以通过植入在脑的GPe中的一个或多个电极递送。 在一些示例中，电刺激装置被配置为基于对患者的睡眠状态的检测将电刺激治疗递送给GPe。 睡眠状态可以包括例如患者清醒并打算睡觉的状态，清醒并尝试睡眠或已经开始睡眠。 此外，在一些示例中，电刺激装置被配置为基于检测到患者的清醒状态来向GPe递送电刺激治疗。
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公开(公告)号：US09821162B2
公开(公告)日：2017-11-21
申请号：US14685690
申请日：2015-04-14
Applicant: Medtronic, Inc.
Inventor： Jianping Wu , Rahul Gupta , Dwight E. Nelson
CPC classification number: A61N1/36078 , A61B5/048 , A61B5/4809 , A61B5/4812 , A61B5/4836 , A61N1/0534 , A61N1/36132 , A61N1/36139 , A61N1/36167
Abstract: In some examples, a medical device delivers electrical stimulation to the external portion of the globus pallidus of a brain of a patient in order to treat a sleep impairment of the patient. In some examples, the electrical stimulation may be delivered via one or more electrodes implanted in the GPe of the brain. In some examples, an electrical stimulation device is configured to deliver electrical stimulation therapy to the GPe based on detection of a sleep state of a patient. The sleep state may include, for example, a state in which the patient is awake and intending on sleeping, is awake and attempting to sleep or has initiated sleep. In addition, in some examples, an electrical stimulation device is configured to deliver electrical stimulation therapy to the GPe based on detection of an awake state of a patient.
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Patent Agency Ranking
公开(公告)号：US11083402B2
公开(公告)日：2021-08-10
申请号：US13955367
申请日：2013-07-31
Applicant: Medtronic, Inc.
Inventor： Dwight E. Nelson , Jianping Wu , Rahul Gupta , Yan Zhao
Abstract: In some examples, a processor determines a patient state based on activity of a bioelectrical brain signal of a patient in one or more frequency sub-bands of a frequency band of interest. For example, a processor may determine a patient state based on the power level of a bioelectrical brain signal of the patient in one or more frequency sub-bands of a frequency band, or based on a spectral pattern of a bioelectrical brain signal in a frequency band, such as a shift in a power distribution between sub-bands, a change in the peak frequency within one or more sub-bands, a pattern of the power distribution over one or more frequency sub-bands, or a width or a variability of one or more sub-bands exhibiting a relatively high or low level of activity.
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7.发明授权Method and apparatus for event-triggered reinforcement of a favorable brain state 有权事件触发强化有利脑状态的方法和装置公开(公告)号：US08954152B2
公开(公告)日：2015-02-10
申请号：US13892401
申请日：2013-05-13
Applicant: Medtronic, Inc.
Inventor： Rahul Gupta , Gabriela C. Molnar , Dwight E. Nelson
CPC classification number: A61N1/3606 , A61B5/4064 , A61B5/4082 , A61B5/4094 , A61B5/6868 , A61N1/0529 , A61N1/36025 , A61N1/36064 , A61N1/36067 , A61N1/36071 , A61N1/36082 , A61N1/36139 , A61N1/36167
Abstract: Methods and apparatuses are disclosed for potentiating a favorable brain state that is associated with relief in symptoms of a brain condition. Techniques include monitoring one or more brain signals and detecting an episode of a favorable brain state based on the one or more brain signals, the favorable brain state associated with a decrease in one or more symptoms of a brain condition of the patient. Then, in response to the detection of the favorable brain state episode, electrical stimulation that potentiates the favorable brain state is delivered to the brain of the patient, the electrical stimulation delivered within a window of time opened for detection of each favorable brain state episode.
Abstract translation: 公开了用于增强与大脑状况症状缓解相关的有利的脑状态的方法和装置。 技术包括基于一个或多个脑信号监测一个或多个脑信号和检测有利的脑状态的发作，所述脑信号与患者的脑部状况的一个或多个症状的减少有关的有利的脑状态。 然后，响应于有利的脑状态发作的检测，将有利的脑状态的电刺激递送到患者的大脑，在打开每个有利的脑状态发作的时间窗口内递送电刺激。
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公开(公告)号：US08761890B2
公开(公告)日：2014-06-24
申请号：US13748633
申请日：2013-01-24
Applicant: Medtronic, Inc.
Inventor： Rahul Gupta , Steven M. Goetz , Maciej T. Lazarewicz , Gabriela C. Molnar , Dwight E. Nelson , Jianping Wu
IPC: A61N1/36
CPC classification number: A61N1/36067 , A61N1/36082 , A61N1/36164 , A61N1/36185 , A61N1/37247
Abstract: In one example, the disclosure relates to a method comprising receiving at least one electrical stimulation parameter value defining electrical stimulation for delivery via one or more electrodes to a tissue site, and determining, via one or more processors, a volume of sub-activation threshold impact for tissue from the delivery of the electrical stimulation to the tissue site.
Abstract translation: 在一个示例中，本公开涉及一种方法，包括接收限定电刺激的至少一个电刺激参数值，用于经由一个或多个电极递送至组织部位，以及经由一个或多个处理器确定子激活阈值的量 对组织从电刺激递送到组织部位的影响。
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公开(公告)号：US20130268019A1
公开(公告)日：2013-10-10
申请号：US13748633
申请日：2013-01-24
Applicant: MEDTRONIC, INC.
Inventor： Rahul Gupta , Steven M. Goetz , Maciej T. Lazarewicz , Gabriela C. Molnar , Dwight E. Nelson , Jianping Wu
IPC: A61N1/36
CPC classification number: A61N1/36067 , A61N1/36082 , A61N1/36164 , A61N1/36185 , A61N1/37247
Abstract: In one example, the disclosure relates to a method comprising receiving at least one electrical stimulation parameter value defining electrical stimulation for delivery via one or more electrodes to a tissue site, and determining, via one or more processors, a volume of sub-activation threshold impact for tissue from the delivery of the electrical stimulation to the tissue site.
Abstract translation: 在一个示例中，本公开涉及一种方法，包括接收限定电刺激的至少一个电刺激参数值，用于经由一个或多个电极递送至组织部位，以及经由一个或多个处理器确定子激活阈值的量 对组织从电刺激递送到组织部位的影响。
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10.发明授权公开(公告)号：US12178603B2
公开(公告)日：2024-12-31
申请号：US17394355
申请日：2021-08-04
Applicant: Medtronic, Inc.
Inventor： Dwight E. Nelson , Jianping Wu , Rahul Gupta , Yan Zhao
Abstract: In some examples, a processor determines a patient state based on activity of a bioelectrical brain signal of a patient in one or more frequency sub-bands of a frequency band of interest. For example, a processor may determine a patient state based on the power level of a bioelectrical brain signal of the patient in one or more frequency sub-bands of a frequency band, or based on a spectral pattern of a bioelectrical brain signal in a frequency band, such as a shift in a power distribution between sub-bands, a change in the peak frequency within one or more sub-bands, a pattern of the power distribution over one or more frequency sub-bands, or a width or a variability of one or more sub-bands exhibiting a relatively high or low level of activity.
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