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公开(公告)号：US12233059B2
公开(公告)日：2025-02-25
申请号：US18670637
申请日：2024-05-21
Applicant: Alto Neuroscience, Inc.
Inventor： Amit Etkin , Wei Wu , Chao Wang , Nicholas Cooper , Joshua Jordan , Adam Savitz
Abstract: This invention relates to the use of (4-benzylpiperazin-1-yl)-[2-(3-methylbutylamino)pyridin-3-yl]methanone (NSI-189) or a pharmaceutically acceptable salt thereof in the treatment of a psychiatric condition in which depressive symptoms are prominent, including major depressive disorder (MDD), bipolar disorder, post-traumatic stress disorder, substance use disorder, and depression-related aspects of schizophrenia (e.g. negative symptoms) in select patients who exhibit impaired learning and/or memory. The invention also relates to the use of NSI-189 or a pharmaceutically acceptable salt thereof in the treatment of a psychiatric condition in which depressive symptoms are prominent, including major depressive disorder (MDD), in select patients who exhibit impaired learning and/or memory or certain EEG characteristics.
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公开(公告)号：US20250049378A1
公开(公告)日：2025-02-13
申请号：US18933040
申请日：2024-10-31
Applicant: Christine Ramos
Inventor： Christine Ramos
IPC: A61B5/374 , A61B5/00 , A61B5/0205 , A61B90/00
Abstract: A system for increasing neural synchrony by using biofeedback includes first and second EEG headsets configured to detect neural activity in first and second users, respectively, during at least one biofeedback monitoring session. A computer is in communication with the first and second EEG headsets. The computer is configured to receive a first data set from the first EEG headset. The first data set includes data of the neural activity of the first user. The computer is configured to receive a second data set from the second EEG headset. The second data set includes data of the neural activity of the second user. The computer is configured to compare the first data set with the second data set. The computer is configured to identify an occurrence of neural synchrony between a parent and child, display neural synchrony data in real-time, and to increase parent-child neural synchrony by utilizing biofeedback.
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公开(公告)号：US20250009280A1
公开(公告)日：2025-01-09
申请号：US18893592
申请日：2024-09-23
Applicant: The Trustees of Columbia University in the City of New York , The Nathan S. Kline Institute for Psychiatric Research
Inventor： Daniel Javitt , Antigona Martinez , Yaakov Stern
Abstract: An exemplary system, method, and computer-accessible medium for generating diagnostic data associated with a likelihood a patient(s) developing a mental disease(s) can be provided, which can include, for example, providing a visual patterns to the patient(s), receiving electroencephalogram (EEG) information from the patient(s) that can be based on the visual pattern(s); and generating the diagnostic data based on the EEG information.
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公开(公告)号：US12186089B2
公开(公告)日：2025-01-07
申请号：US18329476
申请日：2023-06-05
Applicant: Synchron Australia Pty Limited
Inventor： Idan Tal , Peter Eli Yoo
Abstract: Systems, methods, and apparatus for controlling a device based on the detection of transient oscillatory or pseudo-oscillatory bursts are disclosed. For example, a method can comprise detecting one or more transient oscillatory or pseudo-oscillatory bursts from an ongoing neural signal recording of a subject. The method can also comprise extracting one or more burst features from the one or more transient oscillatory or pseudo-oscillatory bursts detected within a detection period. The method can also comprise predicting a thought generated or conjured by the subject or a change in mental state evoked by the subject by applying at least one of a machine learning algorithm and a feature threshold to the one or more burst features extracted within the detection period. An input command associated with the prediction can be transmitted to the device in order to control the device.
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公开(公告)号：US20250000429A1
公开(公告)日：2025-01-02
申请号：US18883987
申请日：2024-09-12
Applicant: Universiteit van Amsterdam , Okazolab Ltd
Inventor： Lucia Maddalena TALAMINI , Ilia Korjoukov
Abstract: The invention provides an assembly comprising: a recording assembly for recording a time-based brain-related signal; a stimulus generator for providing a stimulus, and a computer assembly, functionally coupled to said recording assembly and to said stimulus generator, said computer assembly comprising: a memory for storing at least a data segment of said time-based brain-related signal during recording of said time-based brain-related signal, and a computer program which, when running on said computer assembly, functionally real-time performs: retrieving a most-recent data segment of said stored data segment of said time-based brain-related signal; fitting at least one curve to said retrieved most-recent data segment; predicting a future continuation of said most-recent data segment using said at least one curve fitted to said most-recent data segment; detecting a predefined pattern in said predicted future continuation for predicting occurrence of said predefined pattern, and defining a predicted event time of said predefined pattern, said predicted event time being in the future with respect to said most-recent data segment, and actuating said stimulus generator for providing a stimulus within a predefined event time window of said predicted event time.
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Patent Agency Ranking
公开(公告)号：US20240416122A1
公开(公告)日：2024-12-19
申请号：US18762572
申请日：2024-07-02
Applicant: Newronika S.p.A.
Inventor： Daniel SENDEROWICZ , Mattia ARLOTTI , Nicolo´ VIENO , Lorenzo ROSSI
IPC: A61N1/36 , A61B5/00 , A61B5/30 , A61B5/305 , A61B5/31 , A61B5/316 , A61B5/374 , A61N1/05 , A61N1/16
Abstract: Disclosed herein are apparatuses and methods for treating neurological disorders by electro-stimulation. The apparatus (10) for treating neurological disorders includes at least one electrode (12) implantable in the brain of a patient, and a processing and stimulation device (14) connected to the at least one electrode (12). The processing and stimulation device (14) may include a stimulation module (16) configured to generate a stimulation signal to be sent to the at least one electrode (12), and an acquisition module (20) that measures cerebral activity coming from the brain of the patient. The acquisition module (20) may have a front-end block (27) configured to amplify the potential difference of its input signals (V1a, V2a) and to filter a stimulus artifact and may include a multi-stage fully-differential switched capacitor circuit (e.g., an integrated circuit) configured for discrete-time signal processing.
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公开(公告)号：US20240400114A1
公开(公告)日：2024-12-05
申请号：US18327635
申请日：2023-06-01
Inventor： Raymond P. Viviano
Abstract: A vehicle control system is provided for use with a semi-autonomous vehicle. The vehicle control system includes: a hazard-detection system configured to output a hazard-detection signal based on a detected hazard; an eye-tracking system configured to output an eye-tracking signal based on where the driver is looking; a brain-function system configured to output a brain-function signal based on a detected parameter; and a driving-control system configured to determine whether the driver comprehends the hazard based on the hazard-detection signal, the eye-tracking signal and the brain-function signal, and operate in a driver-controlled state so as to enable the driver to control at least one of steering of the semi-autonomous vehicle, breaking of the semi-autonomous vehicle, and a combination thereof, and a driving-control-system-controlled state so as to enable the driving-control system to control the at least one of steering of the semi-autonomous vehicle, breaking of the semi-autonomous vehicle, and a combination thereof.
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公开(公告)号：US20240374218A1
公开(公告)日：2024-11-14
申请号：US18781872
申请日：2024-07-23
Applicant: WAVE NEUROSCIENCE, INC.
Inventor： Yi JIN
Abstract: Described are novel systems for the diagnosis of specific mental disorders using neurometrics. EEG parameters are compared to thresholds to determine if a person is suffering from autism spectrum disorder. Alzheimer's disease, anxiety, depression, or schizophrenia.
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公开(公告)号：US12114964B2
公开(公告)日：2024-10-15
申请号：US16883387
申请日：2020-05-26
Applicant: TOHOKU UNIVERSITY
Inventor： Makoto Yoshizawa , Norihiro Sugita
CPC classification number: A61B5/02116 , A61B5/02416 , A61B5/347 , A61B5/374 , A61B5/7257 , A61B5/7278 , A61B5/7435
Abstract: A biological information measuring apparatus includes a distortion calculating unit that calculates, based on video pulse wave information representing a video pulse wave expressing a temporal change in a brightness value included in a video signal of a predetermined part of a subject, a waveform distortion obtained from a heartbeat basic component containing a frequency component of a heartbeat frequency band corresponding to a heart rate of the subject and a heartbeat high-frequency component related to a waveform of a pulse wave and containing a frequency component of a frequency band higher than the heartbeat frequency band, the heartbeat basic component and the heartbeat high-frequency component being included in the video pulse wave; and a measuring unit that measures a fluctuation in a blood pressure of the subject based on the waveform distortion calculated by the distortion calculating unit.
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10.发明公开公开(公告)号：US20240315635A1
公开(公告)日：2024-09-26
申请号：US18734876
申请日：2024-06-05
Applicant: Covidien LP
Inventor： Susanne Koch , Claudia Spies
Abstract: The present disclosure relates to methods and devices for providing parameters that indicate a higher likelihood of a postoperative delirium occurring. According to an aspect of the present disclosure, the following steps are provided: detecting at least one EEG signal at the head of the patient; determining the average amplitude of the “direct current” EEG signal; checking whether an increase in the determined average amplitude when entering anesthetic-induced loss of consciousness is above a predefined amount, and in the event of this, providing a corresponding information in the form of a parameter that shows a higher likelihood of a postoperative delirium occurring.
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