公开(公告)号：US20220140341A1

公开(公告)日：2022-05-05

申请号：US17434540

申请日：2020-02-25

Applicant: NITTO DENKO CORPORATION ,  National Institute of Advanced Industrial Science and Technology

Inventor： Motoki HAISHI ,  Mitsunobu TAKEMOTO ,  Tatsuya KITAHARA ,  Kentaro TAKEDA ,  Dai KATO ,  Tomoyuki KAMATA

IPC: H01M4/583 ,  H01M4/62 ,  H01M4/36

Abstract: A carbon electrode includes a substrate, and a conductive carbon layer disposed at an upper side of the substrate and having an sp2 bond and an sp3 bond. On an upper surface of the conductive carbon layer, the concentration ratio of oxygen to carbon is 0.07 or more. The ratio of a number of sp3 bonded carbon atoms to the sum of a number of sp2 bonded carbon atoms and the number of sp3 bonded carbon atoms is 0.35 or more.

公开(公告)号：US20220214299A1

公开(公告)日：2022-07-07

申请号：US17598969

申请日：2020-03-25

Applicant: NITTO DENKO CORPORATION ,  NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY

Inventor： Kazuto YAMAGATA ,  Motoki HAISHI ,  Mitsunobu TAKEMOTO ,  Koya OSUKA ,  Dai KATO ,  Tomoyuki KAMATA

IPC: G01N27/30 ,  G01N27/48

Abstract: A carbon electrode includes a substrate, and a conductive carbon layer disposed at an upper side of the substrate and having an sp2 bond and an sp3 bond. On an upper surface of the conductive carbon layer, the concentration ratio of oxygen to carbon is 0.07 or more. The ratio of a number of sp3 bonded carbon atoms to the sum of a number of sp2 bonded carbon atoms and the number of sp3 bonded carbon atoms is 0.35 or more.

公开(公告)号：US20220026424A1

公开(公告)日：2022-01-27

申请号：US17431128

申请日：2020-02-26

Applicant: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY

Inventor： Hyonchol KIM ,  Dai KATO ,  Naoshi KOJIMA ,  Shohei YAMAMURA ,  Tomoyuki KAMATA

IPC: G01N33/543 ,  G01N21/66 ,  G01N33/574 ,  G01N33/553

Abstract: In order to provide a specific solution for producing a microstructure equipped with a mechanism for selectively detecting a marker molecule expressed by a target cell, or a specific biomolecule, and for detecting and identifying a molecule to be detected using the microstructure, the present invention provides a nearly hemispherical shell-shaped structure made of a first conductive material, and an electrode layer made of a second conductive material disposed on the concave side of the nearly hemispherical shell-shaped structure, wherein the first conductive material includes a magnetic material and the second conductive material includes an electrode material, and the size (diameter) of the cavity surrounded by the electrode layer on the concave side of the nearly hemispherical shell-shaped structure is in the range of about 10 nm to about 50 μm.

公开(公告)号：US20230294088A1

公开(公告)日：2023-09-21

申请号：US18017632

申请日：2021-07-29

Applicant: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY ,  KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION

Inventor： Hyonchol KIM ,  Dai KATO ,  Chikashi NAKAMURA ,  Man Bock GU ,  Cheul Min Joe

IPC: B01L3/00 ,  G01N33/543 ,  G01N33/553

CPC classification number: B01L3/502707 ,  G01N33/54326 ,  G01N33/553 ,  B01L2300/08 ,  G01N2021/6432

Abstract: To provide a microstructure equipped with a mechanism for selectively detecting marker molecules expressed or secreted by individual cells forming a cell population, a method for fabricating such a microstructure, and specific solutions for detecting and identifying molecules to be detected using such a microstructure, the present invention provides a method for fabricating a hemispherical shell-shaped microstructure made of a thin film of a desired thickness and diameter, in which a material surface capable of fixing a probe for detecting a biomolecule is arranged on the inner surface, and a method for detecting a target biomolecule using such a thin film.