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1.发明授权Apparatus, method and operating method of apparatus for excluding non-target-region of fluorescence 有权用于排除非目标区荧光的装置的方法和操作方法公开(公告)号：US09519967B2
公开(公告)日：2016-12-13
申请号：US14312956
申请日：2014-06-24
Applicant: OLYMPUS CORPORATION
Inventor： Hiromi Shida , Yasushige Ishihara , Satoshi Takekoshi , Kei Kubo
CPC classification number: G06T7/0014 , A61B1/00009 , A61B1/043 , G02B21/16 , G02B23/2461 , G02B23/2484 , G06K9/46 , G06K2009/4666
Abstract: Fluorescence generated at a lesion is distinguished from fluorescence generated at portions other than the lesion, and thus, observation is performed by using only the fluorescence generated at the lesion. Provided is a fluorescence observation apparatus including a light radiating portion that radiates excitation light onto an examination subject; a fluorescence-distribution acquiring portion that acquires an intensity distribution of fluorescence generated at the examination subject due to irradiation with the excitation light from the light radiating portion; and a non-target-region excluding portion that, in the fluorescence-intensity distribution acquired by the fluorescence-distribution acquiring portion, excludes regions in which a spectrum in a specific wavelength band has changed due to a specific biological component whose concentration in a lesion is lower than in other portions.
Abstract translation: 在损伤处产生的荧光与病变以外的部分产生的荧光不同，因此仅使用在病变处产生的荧光进行观察。 本发明提供一种荧光观察装置，其包括将激发光照射到检查对象上的光照射部， 荧光分布获取部分，其获取由于来自所述光辐射部分的激发光的照射而在所述检查对象产生的荧光的强度分布; 以及在由荧光分布获取部获取的荧光强度分布中排除由特定生物成分在特定波长带中的光谱变化的区域的非靶区域排除部分， 低于其他部分。
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公开(公告)号：US09532719B2
公开(公告)日：2017-01-03
申请号：US14154243
申请日：2014-01-14
Applicant: OLYMPUS CORPORATION
Inventor： Hiromi Shida
CPC classification number: A61B5/0071 , A61B1/00009 , A61B1/043 , A61B1/0638 , A61B1/0646 , A61B1/0661 , G02B21/16 , G02B21/244 , G02B23/2469 , G06T5/50 , G06T2207/10064 , G06T2207/10068 , G06T2207/30004
Abstract: A fluorescence endoscope apparatus includes a light source that radiates excitation light and reference light onto an examination target; a fluorescence-image generating portion that generates a fluorescence image by capturing fluorescence generated at the examination target due to irradiation with the excitation light; a reference-image generating portion that generates a reference image by capturing return light that returns from the examination target due to irradiation with the reference light; a division-image generating portion that generates a division image by dividing the fluorescence image generated by the fluorescence-image generating portion by the reference image generated by the reference-image generating portion; and a corrected-image generating portion that generates a corrected image based on the division image and the fluorescence image, wherein the corrected-image generating portion generates a corrected image in which a region that has relatively high luminance and that the division image and the fluorescence image have in common is emphasized.
Abstract translation: 荧光内窥镜装置包括将激发光和参考光照射到检查对象物上的光源; 荧光图像生成部，其通过利用激发光的照射捕获在检查对象物上产生的荧光来生成荧光图像; 参考图像生成部，其通过捕获由于被参考光的照射而从检查对象返回的返回光来生成参照图像; 分割图像生成部，其通过将由所述荧光图像生成部生成的荧光图像除以由所述参照图像生成部生成的参照图像而生成分割图像; 以及校正图像生成部，其基于所述分割图像和所述荧光图像生成校正图像，其中，所述校正图像生成部生成其中具有相对高的亮度的区域以及所述分割图像和所述荧光的校正图像 图像有共同点。
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公开(公告)号：US09313388B2
公开(公告)日：2016-04-12
申请号：US13869210
申请日：2013-04-24
Applicant: OLYMPUS CORPORATION
Inventor： Hiromi Shida
CPC classification number: H04N5/2256 , A61B1/00009 , A61B1/00186 , A61B1/043 , A61B1/05 , A61B1/0646 , A61B1/0669
Abstract: Provided is a fluorescence observation device comprising an illuminating section that emits excitation light and illumination light onto a subject; a fluorescence-image capturing section that acquires a fluorescence image by image-capturing fluorescence generated in the subject by irradiation with the excitation light from the illuminating section; a return-light-image capturing section that acquires a return-light image by image-capturing return light that returns from the subject by irradiation with the illumination light from the illuminating section; a region extracting section that extracts a high-luminance region in which the fluorescence image acquired by the fluorescence-image capturing section has a gradation level higher than or equal to a set threshold value; and a threshold setting section that sets the threshold value higher as the gradation level of the return-light image acquired by the return-light-image capturing section increases.
Abstract translation: 本发明提供一种荧光观察装置，其包括将激发光和照明光发射到被检体上的照明部; 荧光图像拍摄部，其通过用来自所述照明部的激发光照射而对所述被检体内的荧光进行图像捕捉来获取荧光图像; 返回光图像拍摄部，其通过利用来自所述照明部的照明光的照射从所述被摄体返回的图像拍摄返回光获取所述返回光图像; 区域提取部，其提取由所述荧光图像拍摄部获取的荧光图像具有高于或等于设定阈值的灰度级的高亮度区域; 以及阈值设定部，其随着由返回光图像拍摄部获取的返回光图像的灰度级增加而将阈值设定得较高。
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公开(公告)号：US09588046B2
公开(公告)日：2017-03-07
申请号：US14198671
申请日：2014-03-06
Applicant: OLYMPUS CORPORATION , OLYMPUS MEDICAL SYSTEMS CORP.
Inventor： Yasushige Ishihara , Hiromi Shida , Kei Kubo , Satoshi Takekoshi
CPC classification number: G01N21/64 , A61B1/00009 , A61B1/0005 , A61B1/043 , G01N21/6456 , G06T5/50 , G06T2207/20216
Abstract: Provided is a fluorescence observation apparatus including: a fluorescence image acquisition section and a reference image acquisition section that acquire a fluorescence image and a reference image of a subject, respectively; a division image generation section that generates a division image by dividing an image based on the fluorescence image by an image based on the reference image; a display section that displays a corrected fluorescence image based on the division image; a correction processing section that applies correction processing to at least one of the reference image and the fluorescence image and/or to the division image prior to the generation of the division image or prior to the display of the corrected fluorescence image; an observation condition determination section that determines observation conditions of the subject; and a correction condition setting section that sets parameters regarding the correction processing according to the observation conditions.
Abstract translation: 本发明提供一种荧光观察装置，包括：荧光图像获取部和参考图像获取部，分别获取被检体的荧光图像和参照图像; 分割图像生成部，其通过基于所述参照图像将基于所述荧光图像的图像分割为图像来生成分割图像; 显示部，其基于所述分割图像显示校正的荧光图像; 校正处理部，其在所述分割图像的生成之前或所述校正后的荧光图像的显示之前，对所述参考图像和所述荧光图像和/或所述分割图像中的至少一个进行校正处理; 观察条件确定部，其确定被检体的观察条件; 以及校正条件设定部，其根据观察条件设定关于校正处理的参数。
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Patent Agency Ranking
公开(公告)号：US09392942B2
公开(公告)日：2016-07-19
申请号：US13952954
申请日：2013-07-29
Applicant: OLYMPUS CORPORATION
Inventor： Hiromi Shida , Yasushige Ishihara , Satoshi Takekoshi , Kei Kubo
CPC classification number: A61B5/0033 , A61B1/00009 , A61B1/0005 , A61B1/00055 , A61B1/043 , G06T5/50 , G06T7/0014 , G06T2207/10121 , G06T2207/30088
Abstract: Provided is a fluoroscopy apparatus including a light source that irradiates an observation target with reference light and excitation light; a fluorescence-image generating unit that captures fluorescence emitted from the observation target X irradiated with the excitation light to generate a fluorescence image; a reference-image generating unit that captures return light returning from the observation target irradiated with the reference light to generate a reference image; an image-combining unit that superimposes the fluorescence image on the reference image to generate a combined image; a determining unit that determines whether there is a position with a luminance at or below a predetermined threshold in the reference image; and a notifying unit that, if the determining unit determines that there is a position with a luminance at or below the predetermined threshold, provides notification thereof.
Abstract translation: 本发明提供一种荧光透视设备，包括：用参考光和激发光照射观察目标的光源; 荧光图像生成单元，其捕获从所述观察对象物X发射的荧光，所述荧光被激发光照射，以产生荧光图像; 参考图像生成单元，其捕获从所述观察对象返回的照射了所述基准光的返回光，生成参照图像; 图像合成单元，其将所述荧光图像叠加在所述参考图像上以生成组合图像; 确定单元，确定参考图像中是否存在亮度在预定阈值以下的位置; 以及通知单元，如果所述确定单元确定存在具有或低于所述预定阈值的亮度的位置，则提供通知。
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公开(公告)号：US09949645B2
公开(公告)日：2018-04-24
申请号：US14033687
申请日：2013-09-23
Applicant: OLYMPUS CORPORATION
Inventor： Hiromi Shida , Yasushige Ishihara
CPC classification number: A61B5/0071 , A61B1/00009 , A61B1/0005 , A61B1/043 , G02B23/2469 , G02B2207/113
Abstract: A fluorescence imaging apparatus including: a processor comprising hardware, configured to: specify a processing condition to be used to process a fluorescence image in accordance with treatment-details information indicating specifics of a treatment to be performed on a biological tissue; in a case where a first processing condition is specified, identify a first fluorescence region in the fluorescence image having a predetermined first fluorescence intensity based on the first processing condition; in a case where a second processing condition is specified, identify a second fluorescence region in the fluorescence image having a predetermined second fluorescence intensity based on the second processing condition; and generate a superimposed image by superimposing the first fluorescence region or the second fluorescence region that is identified, with a return-light image at a region in the return-light image corresponding to the first fluorescence region or the second fluorescence region, respectively, that is identified.
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公开(公告)号：US09518924B2
公开(公告)日：2016-12-13
申请号：US14499813
申请日：2014-09-29
Applicant: OLYMPUS CORPORATION
Inventor： Kei Kubo , Yasushige Ishihara , Hiromi Shida , Satoshi Takekoshi
CPC classification number: G01N21/6456 , A61B1/00009 , A61B1/0005 , A61B1/00055 , A61B1/043 , A61B1/045 , F04C2270/041 , G01N2201/124 , G06K9/4604 , G06T7/0012 , G06T2207/30004
Abstract: The invention provides a fluoroscopy apparatus including an image-capturing device that acquires a fluorescence image of a subject; a sensitivity adjusting portion that sets a sensitivity of the image-capturing device to fluorescence on the basis of a gradation value of the fluorescence image; a notifying portion that extracts a lesion part from the fluorescence image acquired by the image-capturing device with the sensitivity set by the sensitivity adjusting portion and presents it to an operator; and a display switching portion that displays the fluorescence image on a display unit when the sensitivity in the image-capturing device is equal to or less than a predetermined threshold and that presents information showing the existence of the lesion part on the notifying portion when the sensitivity is greater than the predetermined threshold.
Abstract translation: 本发明提供一种荧光透视装置，其包括获取被检体的荧光图像的图像捕获装置; 灵敏度调整部，其基于荧光图像的灰度值，将图像拍摄装置的感光度设定为荧光; 通知部，其以由灵敏度调节部设定的灵敏度从由摄像装置获取的荧光图像中提取病变部，并将其呈现给操作者; 以及显示切换部，当所述图像拍摄装置的灵敏度为规定阈值以下时，在所述显示部显示所述荧光图像，并且当所述灵敏度为灵敏度时，在所述通知部显示所述病变部的存在信息 大于预定阈值。
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公开(公告)号：US09516235B2
公开(公告)日：2016-12-06
申请号：US14091673
申请日：2013-11-27
Applicant: OLYMPUS CORPORATION
Inventor： Hiromi Shida
CPC classification number: H04N5/235 , A61B1/00009 , A61B1/0005 , A61B1/043 , G01N21/6456 , G06T7/12 , G06T7/174 , G06T7/246 , G06T2207/10064 , G06T2207/10068 , G06T2207/30004 , G06T2207/30241
Abstract: Provided is a fluorescence observation apparatus including a fluorescence-image generating portion that generates a plurality of fluorescence images by capturing fluorescence from an observation subject at a time interval; a position identifying portion that, in the individual fluorescence images generated by the fluorescence-image generating portion, identifies high-luminance positions having gradation values equal to or greater than a predetermined threshold; a storage portion that stores the high-luminance positions identified by the position identifying portion; a track-image generating portion that generates a track image that has gradation values at the plurality of high-luminance positions stored in the storage portion; and a display portion that displays the track image generated by the track-image generating portion.
Abstract translation: 本发明提供一种荧光观察装置，其包括通过以时间间隔捕获来自观察对象的荧光而生成多个荧光图像的荧光图像生成部， 位置识别部，其在由所述荧光图像生成部生成的各个荧光图像中识别具有等于或大于预定阈值的灰度值的高亮度位置; 存储部，其存储由所述位置识别部识别的高亮度位置; 轨道图像生成部，其生成在存储部中存储的多个高亮度位置具有灰度值的轨迹图像; 以及显示部，显示由轨迹图像生成部生成的轨迹图像。
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公开(公告)号：US09332909B2
公开(公告)日：2016-05-10
申请号：US13942933
申请日：2013-07-16
Applicant: OLYMPUS CORPORATION
Inventor： Kei Kubo , Yasushige Ishihara , Hiromi Shida , Satoshi Takekoshi
CPC classification number: A61B5/0071 , A61B1/00009 , A61B1/043 , A61B1/0638 , A61B1/0646
Abstract: Provided is a fluoroscopy apparatus including a fluorescence-image generating portion that generates a fluorescence image; an identifying portion that identifies a position of a high-luminance region in the fluorescence image; a storage portion that stores the position of the high-luminance region; a detecting portion that detects an amount of change in a physical quantity, which can possibly act as a cause of changes in a property of the high-luminance region, starting from a time at which the position of the high-luminance region is identified by the identifying portion; a confidence-level calculating portion that calculates a confidence level of the property of the high-luminance region based on the detected amount of change; and a display-image generating portion that generates a display image in which the display mode at the position of the high-luminance region is set in accordance with the confidence level.
Abstract translation: 本发明提供一种荧光透视设备，包括产生荧光图像的荧光图像产生部分; 识别部，其识别所述荧光图像中的高亮度区域的位置; 存储部，其存储高亮度区域的位置; 检测部分，其从高亮度区域的位置的时间开始，从高亮度区域的位置开始，检测出物理量的变化量，其可能充当高亮度区域的性质变化的原因， 识别部分; 置信度计算部，其基于检测出的变化量来计算高亮度区域的属性的置信度; 以及显示图像生成部，其生成根据置信水平设定高亮度区域的位置的显示模式的显示图像。
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