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    REACTION MONITORING
    2.
    发明申请
    REACTION MONITORING 审中-公开

    公开(公告)号：US20180047552A1

    公开(公告)日：2018-02-15

    申请号：US15672862

    申请日：2017-08-09

    Applicant: Purdue Research Foundation

    Inventor： Robert Graham Cooks ,  Xin Yan ,  Christopher Pulliam ,  Ryan M. Bain ,  Tawnya Flick

    IPC: H01J49/00 ,  H01J49/04 ,  G01N33/68 ,  H01J49/16

    CPC classification number: H01J49/0031 ,  G01N33/6848 ,  H01J49/0409 ,  H01J49/165

    Abstract: The invention generally relates to systems and methods for on-line reaction monitoring. In certain embodiments, the invention provides systems that include a reaction vessel having an outlet, a quantitation unit coupled to the outlet and configured to introduce internal standard and solvent into reaction solution flowed from the reaction vessel, one or more ion generating devices that receive flow from the quantitation unit, and a mass spectrometer. In certain embodiments, the invention provides systems for multiple reaction monitoring that include a plurality of reaction vessels, a plurality of ion generating devices, a plurality of channels, each channel coupling a reaction vessel to an ion generating device, an actuator coupled to the plurality of ion generating devices to thereby allow movement of the plurality of ion generating devices, and a mass spectrometer

    REACTION MONITORING
    4.
    发明申请
    REACTION MONITORING 有权

    公开(公告)号：US20220199383A1

    公开(公告)日：2022-06-23

    申请号：US17691294

    申请日：2022-03-10

    Applicant: Purdue Research Foundation

    Inventor： Robert Graham Cooks ,  Xin Yan ,  Christopher Pulliam ,  Ryan M. Bain ,  Tawnya Flick

    IPC: H01J49/00 ,  H01J49/16 ,  H01J49/04 ,  G01N33/68

    Abstract: The invention generally relates to systems and methods for on-line reaction monitoring. In certain embodiments, the invention provides systems that include a reaction vessel having an outlet, a quantitation unit coupled to the outlet and configured to introduce internal standard and solvent into reaction solution flowed from the reaction vessel, one or more ion generating devices that receive flow from the quantitation unit, and a mass spectrometer. In certain embodiments, the invention provides systems for multiple reaction monitoring that include a plurality of reaction vessels, a plurality of ion generating devices, a plurality of channels, each channel coupling a reaction vessel to an ion generating device, an actuator coupled to the plurality of ion generating devices to thereby allow movement of the plurality of ion generating devices, and a mass spectrometer

    PRECURSOR AND NEUTRAL LOSS SCAN IN AN ION TRAP
    6.
    发明申请
    PRECURSOR AND NEUTRAL LOSS SCAN IN AN ION TRAP 审中-公开

    公开(公告)号：US20190066989A1

    公开(公告)日：2019-02-28

    申请号：US15772738

    申请日：2016-11-02

    Applicant: Purdue Research Foundation

    Inventor： Robert Graham Cooks ,  Dalton Snyder ,  Christopher Pulliam

    IPC: H01J49/00 ,  H01J49/42

    Abstract: The invention generally relates to systems and methods for precursor and neutral loss scan in an ion trap. In certain aspects, the invention provides a system that includes a mass spectrometer having an ion trap, and a central processing unit (CPU). The CPU includes storage coupled to the CPU for storing instructions that when executed by the CPU cause the system to excite a precursor ion and eject a product ion in the single ion trap.

    PRECURSOR AND NEUTRAL LOSS SCAN IN AN ION TRAP
    10.
    发明申请
    PRECURSOR AND NEUTRAL LOSS SCAN IN AN ION TRAP 有权

    公开(公告)号：US20220254620A1

    公开(公告)日：2022-08-11

    申请号：US17730830

    申请日：2022-04-27

    Applicant: Purdue Research Foundation

    Inventor： Robert Graham Cooks ,  Dalton Snyder ,  Christopher Pulliam

    IPC: H01J49/00 ,  H01J49/42

    Abstract: The invention generally relates to systems and methods for precursor and neutral loss scan in an ion trap. In certain aspects, the invention provides a system that includes a mass spectrometer having an ion trap, and a central processing unit (CPU). The CPU includes storage coupled to the CPU for storing instructions that when executed by the CPU cause the system to excite a precursor ion and eject a product ion in the single ion trap.

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