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公开(公告)号:US20190169058A1
公开(公告)日:2019-06-06
申请号:US16267553
申请日:2019-02-05
Applicant: Research Triangle Institute
Inventor: Jeffrey Robert Piascik , Charles David Stokes , Ethan Klem , Brian Rhys Stoner , Christopher Gregory , Nicholas G. Baldasaro , Katelyn Lea Sellgren , David E. Rogers , Brian Grant , Brian Thomas Hawkins , Enzo Cellini
Abstract: A solid waste treatment system includes: a solid-liquid separator module configured to receive mixed solid and liquid waste and separating solid material from the mixed solid and liquid waste; an accumulator and macerator module configured to receive and macerate the solid material from the solid-liquid separator module; a drying module configured to receive and dry the macerated solid material from the accumulator and macerator module; and a combustion module configured to receive and combust the dried macerated solid material from the drying module.
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公开(公告)号:US20190169054A1
公开(公告)日:2019-06-06
申请号:US16267420
申请日:2019-02-05
Applicant: Research Triangle Institute
Inventor: Jeffrey Robert Piascik , Charles David Stokes , Ethan Klem , Brian Rhys Stoner , Christopher Gregory , Nicholas G. Baldasaro , Katelyn Lea Sellgren , David E. Rogers , Brian Grant , Brian Thomas Hawkins , Enzo Cellini
Abstract: A liquid waste treatment system includes: a baffle tank subsystem for particle settling; a preprocess tank subsystem downstream of the baffle tank subsystem; a process tank subsystem downstream of the preprocess tank subsystem; and a storage tank subsystem downstream of the process tank subsystem for the storage of treated liquid. A Microbial Fuel Cell (MFC) processing module may be included and may be inserted into the preprocess tank subsystem or implemented in a second process tank downstream of the process tank subsystem. A faster disinfection may occur in the process tank subsystem, and a slower disinfection may occur in the second process tank according to distinct respective kill curves. An electrochemical cell may be operated in a pulse mode in liquid waste in a pulsed mode.
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公开(公告)号:US11213869B2
公开(公告)日:2022-01-04
申请号:US16267553
申请日:2019-02-05
Applicant: Research Triangle Institute
Inventor: Jeffrey Robert Piascik , Charles David Stokes , Ethan Klem , Brian Rhys Stoner , Christopher Gregory , Nicholas G. Baldasaro , Katelyn Lea Sellgren , David E. Rogers , Brian Grant , Brian Thomas Hawkins , Enzo Cellini
Abstract: A solid waste treatment system includes: a solid-liquid separator module configured to receive mixed solid and liquid waste and separating solid material from the mixed solid and liquid waste; an accumulator and macerator module configured to receive and macerate the solid material from the solid-liquid separator module; a drying module configured to receive and dry the macerated solid material from the accumulator and macerator module; and a combustion module configured to receive and combust the dried macerated solid material from the drying module.
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公开(公告)号:US10947139B2
公开(公告)日:2021-03-16
申请号:US16267420
申请日:2019-02-05
Applicant: Research Triangle Institute
Inventor: Jeffrey Robert Piascik , Charles David Stokes , Ethan Klem , Brian Rhys Stoner , Christopher Gregory , Nicholas G. Baldasaro , Katelyn Lea Sellgren , David E. Rogers , Brian Grant , Brian Thomas Hawkins , Enzo Cellini
IPC: C02F1/32 , C02F3/00 , C02F9/00 , C02F1/461 , C02F1/467 , C02F1/48 , C02F3/28 , C02F1/44 , C02F1/00 , C02F103/00 , C02F1/04
Abstract: A liquid waste treatment system includes: a baffle tank subsystem for particle settling; a preprocess tank subsystem downstream of the baffle tank subsystem; a process tank subsystem downstream of the preprocess tank subsystem; and a storage tank subsystem downstream of the process tank subsystem for the storage of treated liquid. A Microbial Fuel Cell (MFC) processing module may be included and may be inserted into the preprocess tank subsystem or implemented in a second process tank downstream of the process tank subsystem. A faster disinfection may occur in the process tank subsystem, and a slower disinfection may occur in the second process tank according to distinct respective kill curves. An electrochemical cell may be operated in a pulse mode in liquid waste in a pulsed mode.
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公开(公告)号:US11147763B2
公开(公告)日:2021-10-19
申请号:US15770722
申请日:2016-10-25
Applicant: RESEARCH TRIANGLE INSTITUTE
Inventor: Leah Marie Johnson , Stephanie Lynn Swarner , Ginger Denison Rothrock , Ariane Van Der Straten Ponthoz , Brian Rhys Stoner
Abstract: The disclosure provides biomedical devices comprising indicator agents sensitive to the environment of use, methods of using same to enhance adherence to a treatment or usage regimen, and systems for monitoring compliance of use of the biomedical device. The biomedical device may be an intravaginal ring comprised of biocompatible polymeric material having indicator agent incorporated therein capable of producing a detectable change in response to a stimulus within the vaginal environment.
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公开(公告)号:US20190070104A1
公开(公告)日:2019-03-07
申请号:US15770722
申请日:2016-10-25
Applicant: RESEARCH TRIANGLE INSTITUTE
Inventor: Leah Marie Johnson , Stephanie Lynn Swarner , Ginger Denison Rothrock , Ariane Van Der Straten Ponthoz , Brian Rhys Stoner
Abstract: The disclosure provides biomedical devices comprising indicator agents sensitive to the environment of use, methods of using same to enhance adherence to a treatment or usage regimen, and systems for monitoring compliance of use of the biomedical device. The biomedical device may be an intravaginal ring comprised of biocompatible polymeric material having indicator agent incorporated therein capable of producing a detectable change in response to a stimulus within the vaginal environment.
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7.
公开(公告)号:US20140308688A1
公开(公告)日:2014-10-16
申请号:US14362942
申请日:2012-12-07
Applicant: Research Triangle Institute
Inventor: Sonia Grego , Brian Rhys Stoner , Kristin Hedgepath Gilchrist , Timothy Raymond Fennell , Ann Pitruzzello
IPC: G01N33/50
CPC classification number: G01N33/5014 , B01L3/502715 , B01L3/50273 , B01L2200/028 , B01L2300/0645 , B01L2400/0481 , B01L2400/0487 , C12M21/08 , C12M23/16 , C12M23/44 , C12M35/08 , G01N33/5082
Abstract: A multiple flow-based microfluidic cell culture system that emulates mammalian physiology is provided. Tissue-mimicking cell cultures are connected by flow within a physiologically meaningful arrangement so that the pharmacokinetics of various agents to be tested in the system emulate in vivo conditions. The system includes at least two organ tissue modules, each organ tissue module including a first chamber containing an organ tissue cell, the first chamber including an inlet and an outlet for flow of an organ tissue cell-specific culture medium; a second chamber including an inlet and an outlet for flow of a blood material; and a semi-permeable membrane separating the first and second chambers. The flow of blood material through each organ tissue module is interconnected and the flow of tissue-cell specific culture medium is directed to a single organ tissue module.
Abstract translation: 提供了一种模拟哺乳动物生理学的基于多流的微流体细胞培养系统。 组织模拟细胞培养物在生理上有意义的排列下通过流动连接,使得在系统中待测试的各种试剂的药代动力学模拟体内条件。 所述系统包括至少两个器官组织模块,每个器官组织模块包括含有器官组织细胞的第一腔室,所述第一腔室包括用于器官组织细胞特异性培养基流动的入口和出口; 第二室,包括用于血液材料流动的入口和出口; 以及分离第一和第二室的半透膜。 通过每个器官组织模块的血液材料的流动相互连接,并且组织细胞特异性培养基的流动被引导到单个器官组织模块。
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