公开(公告)号：US10895580B2

公开(公告)日：2021-01-19

申请号：US15986210

申请日：2018-05-22

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Marco Maetzler ,  Christopher Schofield ,  Ole Lambaek ,  Moritz von Hopffgarten

IPC: G01N35/00 ,  G01N35/10 ,  B01L3/02 ,  G16H10/40

Abstract: A method for operating a laboratory system comprising instruments for processing samples and a control unit connected by a communication network is presented. The method comprises receiving and identifying a biological sample and retrieving an order list from a database. The list comprises a plurality of targets defining one or more processing steps to be carried out on the biological sample by one or more of the laboratory instruments. The method also comprises selecting a workflow strategy and retrieving workflow acceptance criterion corresponding to the workflow strategy. The control unit determines a sample workflow for processing the sample based on the workflow strategy and determines whether the sample workflow satisfies the workflow acceptance criterion. If the sample workflow does not satisfy the workflow acceptance criterion, workflow strategy and the workflow acceptance criterion is refined and the sample workflow is determined again until it satisfies the workflow acceptance criterion.

公开(公告)号：US20170350912A1

公开(公告)日：2017-12-07

申请号：US15600089

申请日：2017-05-19

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Marco Maetzler ,  Liutger Joannes Franzen ,  Florian Zwahlen ,  Hans Reischauer ,  Adrian Cojocaru ,  Stephan Topsakalian

IPC: G01N35/10 ,  G01N35/00 ,  G01N35/04

CPC classification number: G01N35/1002 ,  G01N35/00663 ,  G01N35/00871 ,  G01N35/0099 ,  G01N35/04 ,  G01N2035/0498 ,  G06Q10/087

Abstract: A method for supplying consumable items to an automated sample analyzer is presented. The automated analyzer comprises a consumable repository including two or more storage areas. Each area is configured to store a plurality of consumable items. The method comprises receiving one or more orders for analytical tests to be carried out by the analyzer, reserving consumable items corresponding to one or more sets of consumable items required for the analytical tests in a first area, switching to a second area for reserving consumable items in response to determining that a predetermined consumable item in the first area has been reserved, supplying the reserved consumable items for use in the one or more analytical tests and indicating that the first area can be replenished in response to determining that a particular consumable item of the first storage area has been used.

公开(公告)号：US11733253B2

公开(公告)日：2023-08-22

申请号：US17119307

申请日：2020-12-11

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Marco Maetzler

IPC: G01N35/00

CPC classification number: G01N35/0092 ,  G01N35/00871

Abstract: A method to optimize analyzer use in a laboratory having a plurality of analyzers based on laboratory workload is presented. The method comprises determining current laboratory workload, calculating workload capability of the plurality of analyzers minus one analyzer if the current laboratory workload is below a threshold criteria and if there are two or more analyzers in the plurality of analyzers, masking one of the plurality of analyzers if the current workload is met by the plurality of analyzers minus one analyzer, proceeding with current workload, and repeating the above steps until the current laboratory workload has been completed.

公开(公告)号：US11709172B2

公开(公告)日：2023-07-25

申请号：US17120874

申请日：2020-12-14

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Marco Maetzler ,  Christopher Schofield ,  Ole Lambaek ,  Moritz von Hopffgarten

IPC: G01N35/00 ,  G01N35/10 ,  B01L3/02 ,  G16H10/40

CPC classification number: G01N35/00871 ,  B01L3/021 ,  G01N35/0095 ,  G01N35/00722 ,  G01N35/1016 ,  G16H10/40 ,  B01L2200/14 ,  G01N2035/009 ,  G01N2035/00881

Abstract: A method for operating a laboratory system comprising instruments for processing samples and a control unit connected by a communication network is presented. The method comprises receiving and identifying a biological sample and retrieving an order list from a database. The list comprises a plurality of targets defining one or more processing steps to be carried out on the biological sample by one or more of the laboratory instruments. The method also comprises selecting a workflow strategy and retrieving workflow acceptance criterion corresponding to the workflow strategy. The control unit determines a sample workflow for processing the sample based on the workflow strategy and determines whether the sample workflow satisfies the workflow acceptance criterion. If the sample workflow does not satisfy the workflow acceptance criterion, workflow strategy and the workflow acceptance criterion is refined and the sample workflow is determined again until it satisfies the workflow acceptance criterion.

公开(公告)号：US20180340949A1

公开(公告)日：2018-11-29

申请号：US15986210

申请日：2018-05-22

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Marco Maetzler ,  Christopher Schofield ,  Ole Lambaek ,  Moritz von Hopffgarten

IPC: G01N35/00 ,  G01N35/10 ,  B01L3/02

Abstract: A method for operating a laboratory system comprising instruments for processing samples and a control unit connected by a communication network is presented. The method comprises receiving and identifying a biological sample and retrieving an order list from a database. The list comprises a plurality of targets defining one or more processing steps to be carried out on the biological sample by one or more of the laboratory instruments. The method also comprises selecting a workflow strategy and retrieving workflow acceptance criterion corresponding to the workflow strategy. The control unit determines a sample workflow for processing the sample based on the workflow strategy and determines whether the sample workflow satisfies the workflow acceptance criterion. If the sample workflow does not satisfy the workflow acceptance criterion, workflow strategy and the workflow acceptance criterion is refined and the sample workflow is determined again until it satisfies the workflow acceptance criterion.

公开(公告)号：US20230197212A1

公开(公告)日：2023-06-22

申请号：US18168082

申请日：2023-02-13

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Armin Birrer ,  Marco Maetzler ,  André Peter ,  Ole Lambaek

IPC: G16H10/40 ,  G01N35/00 ,  G06F16/245 ,  G06F16/23

CPC classification number: G16H10/40 ,  G01N35/00732 ,  G06F16/245 ,  G06F16/2365 ,  G01N2035/009 ,  G16H10/60

Abstract: A laboratory system for analyzing biological samples is presented. The laboratory system comprises a plurality of laboratory instruments configured to receive and identify biological samples and to query a laboratory control unit for a processing order indicative of processing steps to be carried out on the biological sample. The laboratory control unit is configured to validate sequence of queries from the plurality of laboratory instruments against a valid query sequence pattern.

公开(公告)号：US20220206023A1

公开(公告)日：2022-06-30

申请号：US17699514

申请日：2022-03-21

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Frederic Furrer ,  Marco Maetzler

IPC: G01N35/00

Abstract: A method of operating an analytical laboratory is presented. The method comprises the steps of: setting a load limit for each laboratory instrument at maximum instrument capacity; dispatching biological samples to laboratory instrument(s) at a dispatch rate not greater than the instrument load limit; each laboratory instrument sending test order queries to the laboratory middleware upon identifying a biological sample; in response to the test order queries transmitting test orders to the laboratory instruments corresponding to the biological samples; the laboratory middleware monitoring a query rate of the plurality of laboratory instruments in order to determine an effective flow rate corresponding to each laboratory instrument; decreasing the load limit of a first laboratory instrument if its effective flow rate is lower than the dispatch rate; increasing the load limit for the first laboratory instrument if its effective flow rate is greater than or equal to the dispatch rate.

公开(公告)号：US20210140987A1

公开(公告)日：2021-05-13

申请号：US17120874

申请日：2020-12-14

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Marco Maetzler ,  Christopher Schofield ,  Ole Lambaek ,  Moritz von Hopffgarten

IPC: G01N35/00 ,  G01N35/10 ,  B01L3/02 ,  G16H10/40

Abstract: A method for operating a laboratory system comprising instruments for processing samples and a control unit connected by a communication network is presented. The method comprises receiving and identifying a biological sample and retrieving an order list from a database. The list comprises a plurality of targets defining one or more processing steps to be carried out on the biological sample by one or more of the laboratory instruments. The method also comprises selecting a workflow strategy and retrieving workflow acceptance criterion corresponding to the workflow strategy. The control unit determines a sample workflow for processing the sample based on the workflow strategy and determines whether the sample workflow satisfies the workflow acceptance criterion. If the sample workflow does not satisfy the workflow acceptance criterion, workflow strategy and the workflow acceptance criterion is refined and the sample workflow is determined again until it satisfies the workflow acceptance criterion.

公开(公告)号：US20160154621A1

公开(公告)日：2016-06-02

申请号：US15018006

申请日：2016-02-08

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Marco Maetzler ,  Juergen Wiemer

IPC: G06F3/14 ,  G06F3/0484

CPC classification number: G06F3/1454 ,  G06F3/04842 ,  G06F3/04845 ,  G06F19/26 ,  G06F19/28

Abstract: Embodiments related to analysis system for analyzing biological samples, a data processing method and a computer program product are disclosed. An analyzer is coupled to an control computer and has a control application program which receives control data, sends analytical data, and generates a host screen image. A remote computer is coupled to the control computer, and provides a data manager application program which sends the control data to the control computer, receives the analytical data, and generates a first window. A remote application program interoperates with a host application program which generates a second window containing a duplicate of the host screen image. A user interface program displays a first display window and a second display window, the first display window being one of the first and second windows and the second display window containing a screen shot of the other one of the first and second windows.

Abstract translation: 公开了与用于分析生物样品的分析系统，数据处理方法和计算机程序产品相关的实施例。 分析器耦合到控制计算机，并且具有控制应用程序，其接收控制数据，发送分析数据并生成主屏幕图像。 远程计算机耦合到控制计算机，并且提供数据管理器应用程序，其将控制数据发送到控制计算机，接收分析数据，并生成第一窗口。 远程应用程序与主机应用程序交互操作，该主机应用程序生成包含主屏幕图像的副本的第二窗口。 用户界面程序显示第一显示窗口和第二显示窗口，第一显示窗口是第一窗口和第二窗口之一，第二显示窗口包含第一窗口和第二窗口中另一窗口的屏幕截图。

公开(公告)号：US20210215731A1

公开(公告)日：2021-07-15

申请号：US17142359

申请日：2021-01-06

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Alejandro Morcillo Montejo ,  Marco Maetzler ,  Juan Bacardit

IPC: G01N35/10

Abstract: A computer-implemented method for processing biological samples in an environment including multiple automated analyzers having multiple modules is presented. The method includes receiving data related to a plurality of orders for processing biological samples at a main workflow engine. The main workflow engine receives and processes data for each of the multiple automated analyzers having multiple modules. The method further includes providing a data snapshot to at least one shadow workflow engine associated with a subset of one or more modules of the multiple modules. The data snapshot comprises only a portion of the data related to the plurality of orders that is necessary to determine actions of the module of the multiple modules. The method further includes determining, by the shadow workflow engine, a plurality of actions for the subset of modules to process the plurality of orders based on the data snapshot.