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公开(公告)号:US20100233034A1
公开(公告)日:2010-09-16
申请号:US12658569
申请日:2010-02-08
IPC分类号: B01L99/00
CPC分类号: B01L3/50255 , B01L2200/02 , B01L2200/12 , B01L2300/0829 , B01L2400/0409 , B01L2400/0487
摘要: The present invention relates to a multiwell plate having a series of wells, each well having an inner bore, an open top and a bottom, the bottom being sealed with a liquid permeable filter, and an insert contained within the inner-bore of each well, each insert having an outer dimension the same or larger than that of the inner bore and a through bore of a dimension less than that of the outer dimension of the insert. The use of inserts allows one to take a standard one-piece plate design with a heat sealed membrane and arrange for a universal plate format. The insert may act as a base for an extension plate that can be adhered, heat sealed or overmolded over the plate top and insert top to form a deep well plate. The plate conforms to the Society of Biological Standards Microplate Standards. Additionally, the inserts may be configured to give one a different well diameter (smaller, tapered, etc), to include various media such as chromatography resins, to include multiple layers of membrane and the like. A variety of inserts may be used in the same plate to create a minilab on a plate that is capable of conducting several steps of a process on the same (e.g (e.g. filter, wash, bind, elute, label, etc).
摘要翻译: 本发明涉及具有一系列井的多孔板,每个孔具有内孔,开口顶部和底部,底部用液体可渗透过滤器密封,并且包含在每个孔的内孔内的插入件 每个插入件具有与内孔相同或更大的外部尺寸和尺寸小于插入件的外部尺寸尺寸的通孔。 使用插入件可以使用带有热密封膜的标准单片板设计,并安排通用板格式。 插入件可以用作延伸板的基部,该延伸板可以在板顶上粘附,热密封或包覆成型,并且插入顶部以形成深孔板。 该板符合生物标准微孔板标准协会。 此外,插入件可以被配置成给出一个不同的孔直径(更小,锥形等),以包括各种介质,例如色谱树脂,以包括多层膜等。 可以在同一板中使用各种插入物以在板上产生能够在相同的过程上进行几个步骤(例如过滤器,洗涤,结合,洗脱,标记等)的小拉伸。
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公开(公告)号:US07658886B2
公开(公告)日:2010-02-09
申请号:US10838588
申请日:2004-05-04
IPC分类号: B01L1/00
CPC分类号: B01L3/50255 , B01L2200/02 , B01L2200/12 , B01L2300/0829 , B01L2400/0409 , B01L2400/0487
摘要: The present invention relates to a multiwell plate having a series of wells, each well having an inner bore, an open top and a bottom, the bottom being sealed with a liquid permeable filter, and an insert contained within the inner bore of each well, each insert having an outer dimension the same or larger than that of the inner bore and a through bore of a dimension less than that of the outer dimension of the insert. The use of inserts allows one to take a standard one-piece plate design with a heat sealed membrane and arrange for a universal plate format. The insert may act as a base for an extension plate that can be adhered, heat sealed or overmolded over the plate top and insert top to form a deep well plate. The plate conforms to the Society of Biological Standards Microplate Standards. Additionally, the inserts may be configured to give one a different well diameter (smaller, tapered, etc), to include various media such as chromatography resins, to include multiple layers of membrane and the like. A variety of inserts may be used in the same plate to create a minilab on a plate that is capable of conducting several steps of a process on the same (e.g (e.g. filter, wash, bind, elute, label, etc).
摘要翻译: 本发明涉及具有一系列井的多孔板,每个孔具有内孔,开口顶部和底部,底部用液体可渗透的过滤器密封,以及包含在每个孔的内孔内的插入件, 每个插入件具有与内孔相同或更大的外部尺寸和尺寸小于插入件的外部尺寸尺寸的通孔。 使用插入件可以使用带有热密封膜的标准单片板设计,并安排通用板格式。 插入件可以用作延伸板的基部,该延伸板可以在板顶上粘附,热密封或包覆成型,并且插入顶部以形成深孔板。 该板符合生物标准微孔板标准协会。 此外,插入件可以被配置成给出一个不同的孔直径(更小,锥形等),以包括各种介质,例如色谱树脂,以包括多层膜等。 可以在同一板中使用各种插入物以在板上产生能够在相同的过程上进行几个步骤(例如过滤器,洗涤,结合,洗脱,标记等)的小拉伸。
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公开(公告)号:US07112281B2
公开(公告)日:2006-09-26
申请号:US11289082
申请日:2005-11-29
IPC分类号: B01D29/92
CPC分类号: B01L3/50255 , B01D61/18 , B01D61/20 , B01L2200/0615 , B01L2300/0829 , B01L2400/0406 , B01L2400/049 , G01N2035/00485 , Y10S210/919
摘要: A device and method for removal of liquid from the downstream side of a membrane or a well, such as a well of a multiwell plate. More specifically, the present invention is directed to a wicking structure, which channels droplets of liquid away from a membrane in communication with a plurality of wells. In the preferred embodiment, the wicking structure is placed in a manifold.
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公开(公告)号:US06989099B2
公开(公告)日:2006-01-24
申请号:US11061202
申请日:2005-02-18
IPC分类号: B01D29/92
CPC分类号: B01L3/50255 , B01D61/18 , B01D61/20 , B01L2200/0615 , B01L2300/0829 , B01L2400/0406 , B01L2400/049 , G01N2035/00485 , Y10S210/919
摘要: A device and method for removal of liquid from the downstream side of a membrane or a well, such as a well of a multiwell plate. More specifically, the present invention is directed to a wicking structure, which channels droplets of liquid away from a membrane in communication with a plurality of wells. In the preferred embodiment, the wicking structure is placed in a manifold.
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公开(公告)号:US06893562B2
公开(公告)日:2005-05-17
申请号:US09565963
申请日:2000-05-05
IPC分类号: G01N33/48 , B01D61/18 , B01L3/00 , C12M1/00 , C12M1/12 , C12N15/09 , G01N1/10 , G01N1/28 , G01N35/00 , B01D29/92
CPC分类号: B01L3/50255 , B01D61/18 , B01D61/20 , B01L2200/0615 , B01L2300/0829 , B01L2400/0406 , B01L2400/049 , G01N2035/00485 , Y10S210/919
摘要: A device and method for removal of liquid from the downstream side of a membrane or a well, such as a well of a multiwell plate. More specifically, the present invention is directed to a wicking structure, which channels droplets of liquid away from a membrane in communication with a plurality of wells. In the preferred embodiment, the wicking structure is placed in a manifold.
摘要翻译: 一种用于从膜或井的下游侧除去液体的装置和方法,例如多孔板的孔。 更具体地,本发明涉及芯吸结构,其将液体的液滴远离与多个孔连通的膜。 在优选实施例中,芯吸结构被放置在歧管中。
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