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公开(公告)号：US07658886B2
公开(公告)日：2010-02-09
申请号：US10838588
申请日：2004-05-04
IPC分类号： B01L1/00
CPC分类号： B01L3/50255 , B01L2200/02 , B01L2200/12 , B01L2300/0829 , B01L2400/0409 , B01L2400/0487
摘要： The present invention relates to a multiwell plate having a series of wells, each well having an inner bore, an open top and a bottom, the bottom being sealed with a liquid permeable filter, and an insert contained within the inner bore of each well, each insert having an outer dimension the same or larger than that of the inner bore and a through bore of a dimension less than that of the outer dimension of the insert. The use of inserts allows one to take a standard one-piece plate design with a heat sealed membrane and arrange for a universal plate format. The insert may act as a base for an extension plate that can be adhered, heat sealed or overmolded over the plate top and insert top to form a deep well plate. The plate conforms to the Society of Biological Standards Microplate Standards. Additionally, the inserts may be configured to give one a different well diameter (smaller, tapered, etc), to include various media such as chromatography resins, to include multiple layers of membrane and the like. A variety of inserts may be used in the same plate to create a minilab on a plate that is capable of conducting several steps of a process on the same (e.g (e.g. filter, wash, bind, elute, label, etc).
摘要翻译： 本发明涉及具有一系列井的多孔板，每个孔具有内孔，开口顶部和底部，底部用液体可渗透的过滤器密封，以及包含在每个孔的内孔内的插入件， 每个插入件具有与内孔相同或更大的外部尺寸和尺寸小于插入件的外部尺寸尺寸的通孔。 使用插入件可以使用带有热密封膜的标准单片板设计，并安排通用板格式。 插入件可以用作延伸板的基部，该延伸板可以在板顶上粘附，热密封或包覆成型，并且插入顶部以形成深孔板。 该板符合生物标准微孔板标准协会。 此外，插入件可以被配置成给出一个不同的孔直径（更小，锥形等），以包括各种介质，例如色谱树脂，以包括多层膜等。 可以在同一板中使用各种插入物以在板上产生能够在相同的过程上进行几个步骤（例如过滤器，洗涤，结合，洗脱，标记等）的小拉伸。
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公开(公告)号：US20100233034A1
公开(公告)日：2010-09-16
申请号：US12658569
申请日：2010-02-08
IPC分类号： B01L99/00
CPC分类号： B01L3/50255 , B01L2200/02 , B01L2200/12 , B01L2300/0829 , B01L2400/0409 , B01L2400/0487
摘要： The present invention relates to a multiwell plate having a series of wells, each well having an inner bore, an open top and a bottom, the bottom being sealed with a liquid permeable filter, and an insert contained within the inner-bore of each well, each insert having an outer dimension the same or larger than that of the inner bore and a through bore of a dimension less than that of the outer dimension of the insert. The use of inserts allows one to take a standard one-piece plate design with a heat sealed membrane and arrange for a universal plate format. The insert may act as a base for an extension plate that can be adhered, heat sealed or overmolded over the plate top and insert top to form a deep well plate. The plate conforms to the Society of Biological Standards Microplate Standards. Additionally, the inserts may be configured to give one a different well diameter (smaller, tapered, etc), to include various media such as chromatography resins, to include multiple layers of membrane and the like. A variety of inserts may be used in the same plate to create a minilab on a plate that is capable of conducting several steps of a process on the same (e.g (e.g. filter, wash, bind, elute, label, etc).
摘要翻译： 本发明涉及具有一系列井的多孔板，每个孔具有内孔，开口顶部和底部，底部用液体可渗透过滤器密封，并且包含在每个孔的内孔内的插入件 每个插入件具有与内孔相同或更大的外部尺寸和尺寸小于插入件的外部尺寸尺寸的通孔。 使用插入件可以使用带有热密封膜的标准单片板设计，并安排通用板格式。 插入件可以用作延伸板的基部，该延伸板可以在板顶上粘附，热密封或包覆成型，并且插入顶部以形成深孔板。 该板符合生物标准微孔板标准协会。 此外，插入件可以被配置成给出一个不同的孔直径（更小，锥形等），以包括各种介质，例如色谱树脂，以包括多层膜等。 可以在同一板中使用各种插入物以在板上产生能够在相同的过程上进行几个步骤（例如过滤器，洗涤，结合，洗脱，标记等）的小拉伸。
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公开(公告)号：US08668673B2
公开(公告)日：2014-03-11
申请号：US11258478
申请日：2005-10-25
申请人： Stephane Olivier , Jerome Geyer , Gerard Muller
发明人： Stephane Olivier , Jerome Geyer , Gerard Muller
IPC分类号： A61M5/178
CPC分类号： B23P19/04 , A61B17/3417 , A61B17/3421 , A61M5/158 , A61M5/162 , A61M25/06 , A61M25/065 , A61M2005/1623 , Y10T29/49826 , Y10T29/49892 , Y10T29/49895 , Y10T29/49897 , Y10T29/49899 , Y10T29/49947
摘要： A take-off needle comprises a hollow lance having a distal end adapted to perform a insertion operation, said hollow lance being connected to at least one pipe provided with a spigot for it to be connected to a tube, and comprising a body for holding the hollow lance and pipe relative to each other such that the spigot projects from the holding body, said needle further comprising two flanges held on respective sides of and spaced from the holding body by virtue of a spacer disposed between each flange and the holding body, said flanges extending in a longitudinal direction from the spigot to the vicinity of the proximal end of the hollow lance, the width of each flange being greater than the width of the portion of the holding body facing the flanges.
摘要翻译： 起飞针包括具有适于执行插入操作的远端的中空喷枪，所述中空喷枪连接到至少一个设置有插口的管子，以将其连接到管，并且包括用于保持 相对于彼此的中空喷枪和管道，使得插口从保持体突出，所述针还包括两个凸缘，该两个凸缘由于设置在每个凸缘和保持体之间的间隔件而保持在保持体的相应侧并与其间隔开，所述 凸缘从纵向方向延伸到中空喷枪的近端附近，每个凸缘的宽度大于保持体面对凸缘的部分的宽度。
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公开(公告)号：US4795249A
公开(公告)日：1989-01-03
申请号：US90468
申请日：1987-08-28
申请人： Gerard Muller
发明人： Gerard Muller
摘要： The contact lens comprises a central optical zone and a peripheral zone for fastening the lens. For centering said lens the peripheral zone comprises two stabilizing bosses which are disposed on the horizontal stabilization axis of the lens. For large palpebral openings it may be preferable to use two pairs of bosses, whereby each pair comprises two bosses, disposed symmetrically to said axis of stabilization. For multifocal corrections it is possible to use a third boss, disposed on the vertical axis of the lens. These stabilizers allow a perfect centering of the lens, hindering its rotation and the use of very thin lenses.
摘要翻译： 隐形眼镜包括中心光学区域和用于紧固透镜的周边区域。 为了对准所述透镜，周边区域包括设置在透镜的水平稳定轴线上的两个稳定凸台。 对于大的睑缘开口，可能优选使用两对凸起部，由此每对凸起部包括与所述稳定轴对称设置的两个凸台。 对于多焦点校正，可以使用设置在透镜的垂直轴上的第三凸台。 这些稳定器可以使镜头完美对中，阻碍其旋转和使用非常薄的透镜。
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5.发明授权Method and instrument for unlocking a device having two axially latched bodies 失效用于解锁具有两个轴向锁定体的装置的方法和装置公开(公告)号：US07062833B2
公开(公告)日：2006-06-20
申请号：US10491058
申请日：2002-10-09
CPC分类号： B25B27/00 , Y10T29/49815 , Y10T29/49822 , Y10T29/49824 , Y10T29/5367 , Y10T29/53683
摘要： The method includes the step of positioning the device on a sheath (94) having, for each latching tab (7), a portion adapted to be housed between this tab and a cylindrical wall of the device; the step of making the sheath enter between each tab and the cylindrical wall until means preventing the withdrawal of the tabs are released; and the step of moving the two bodies (2,3) away from each other. The instrument has, in addition to the sheath (94), a guidance slide (77).
摘要翻译： 该方法包括将装置定位在护套（94）上的步骤，对于每个卡扣片（7）具有适于容纳在该突片和该装置的圆柱形壁之间的部分; 使护套进入每个翼片和圆柱形壁之间的步骤直到防止翼片撤回的手段被释放; 以及将两个物体（2,3）彼此移开的步骤。 除了护套（94）之外，仪器具有导向滑块（77）。
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公开(公告)号：US4859049A
公开(公告)日：1989-08-22
申请号：US90468
申请日：1987-08-28
申请人： Gerard Muller
发明人： Gerard Muller
摘要： The contact lens comprises a central optical zone and a peripheral zone for fastening the lens. For centering said lens the peripheral zone comprises two stabilizing bosses which are disposed on the horizontal stabilization axis of the lens. For large palpebral openings it may be preferable to use two pairs of bosses, whereby each pair comprises two bosses, disposed symmetrically to said axis of stabilization. For multifocal corrections it is possible to use a third boss, disposed on the vertical axis of the lens. These stabilizers allow a perfect centering of the lens, hindering its rotation and the use of very thin lenses.
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公开(公告)号：US08182766B2
公开(公告)日：2012-05-22
申请号：US12658569
申请日：2010-02-08
IPC分类号： B01L3/00
CPC分类号： B01L3/50255 , B01L2200/02 , B01L2200/12 , B01L2300/0829 , B01L2400/0409 , B01L2400/0487
摘要： The present invention relates to a multiwell plate having a series of wells, each well having an inner bore, an open top and a bottom, the bottom being sealed with a liquid permeable filter, and an insert contained within the inner bore of each well, each insert having an outer dimension the same or larger than that of the inner bore and a through bore of a dimension less than that of the outer dimension of the insert. The use of inserts allows one to take a standard one-piece plate design with a heat sealed membrane and arrange for a universal plate format. The insert may act as a base for an extension plate that can be adhered, heat sealed or overmolded over the plate top and insert top to form a deep well plate. The plate conforms to the Society of Biological Standards Microplate Standards. Additionally, the inserts may be configured to give one a different well diameter (smaller, tapered, etc), to include various media such as chromatography resins, to include multiple layers of membrane and the like. A variety of inserts may be used in the same plate to create a minilab on a plate that is capable of conducting several steps of a process on the same (e.g (e.g. filter, wash, bind, elute, label, etc).
摘要翻译： 本发明涉及具有一系列井的多孔板，每个孔具有内孔，开口顶部和底部，底部用液体可渗透的过滤器密封，以及包含在每个孔的内孔内的插入件， 每个插入件具有与内孔相同或更大的外部尺寸和尺寸小于插入件的外部尺寸尺寸的通孔。 使用插入件可以使用带有热密封膜的标准单片板设计，并安排通用板格式。 插入件可以用作延伸板的基部，该延伸板可以在板顶上粘附，热密封或包覆成型，并且插入顶部以形成深孔板。 该板符合生物标准微孔板标准协会。 此外，插入件可以被配置成给出一个不同的孔直径（更小，锥形等），以包括各种介质，例如色谱树脂，以包括多层膜等。 可以在同一板中使用各种插入物以在板上产生能够在相同的过程上进行几个步骤（例如过滤器，洗涤，结合，洗脱，标记等）的小拉伸。
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公开(公告)号：US20060089047A1
公开(公告)日：2006-04-27
申请号：US11258478
申请日：2005-10-25
申请人： Stephane Olivier , Jerome Geyer , Gerard Muller
发明人： Stephane Olivier , Jerome Geyer , Gerard Muller
IPC分类号： H01R13/40
CPC分类号： B23P19/04 , A61B17/3417 , A61B17/3421 , A61M5/158 , A61M5/162 , A61M25/06 , A61M25/065 , A61M2005/1623 , Y10T29/49826 , Y10T29/49892 , Y10T29/49895 , Y10T29/49897 , Y10T29/49899 , Y10T29/49947
摘要： A take-off needle comprises a hollow lance having a distal end adapted to perform a insertion operation, said hollow lance being connected to at least one pipe provided with a spigot for it to be connected to a tube, and comprising a body for holding the hollow lance and pipe relative to each other such that the spigot projects from the holding body, said needle further comprising two flanges held on respective sides of and spaced from the holding body by virtue of a spacer disposed between each flange and the holding body, said flanges extending in a longitudinal direction from the spigot to the vicinity of the proximal end of the hollow lance, the width of each flange being greater than the width of the portion of the holding body facing the flanges.
摘要翻译： 起飞针包括具有适于执行插入操作的远端的中空喷枪，所述中空喷枪连接到至少一个设置有插口的管子，以将其连接到管，并且包括用于保持 相对于彼此的中空喷枪和管道，使得插口从保持体突出，所述针还包括两个凸缘，该两个凸缘由于设置在每个凸缘和保持体之间的间隔件而保持在保持体的相应侧并与其间隔开，所述 凸缘从纵向方向延伸到中空喷枪的近端附近，每个凸缘的宽度大于保持体面对凸缘的部分的宽度。
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公开(公告)号：US5782241A
公开(公告)日：1998-07-21
申请号：US537786
申请日：1995-10-23
IPC分类号： A61B5/0408 , A61B5/024 , A61B5/0402 , A61B5/0404 , A61B5/0428 , A61B5/0478 , A61B5/0492 , A61B5/055 , G01R33/567
CPC分类号： A61B5/6831 , A61B5/02438 , A61B5/0404 , A61B5/0428 , A61B5/055 , G01R33/5673 , A61B2562/182 , Y10S128/908
摘要： A sensor device intended to be implemented at the vicinity or inside a nuclear magnetic resonance apparatus, and more particularly on a patient inside the canal of the magnet of a magnetic resonance imager (MRI). The device includes at least two non-metal electrodes intended to be applied to the skin of a patient, and an electro-optical conversion, amplification and filtering module for the electric signals received from the heart by the electrodes. The module is arranged in a shielded casing forming a Faraday cage, and optically connected to a display and/or monitoring apparatus. A support body made of non-magnetic material carries the electrode and the shielded casing containing the module.
摘要翻译： PCT No.PCT / FR94 / 00454 Sec。 371日期1995年10月23日第 102（e）1995年10月23日PCT PCT 1994年4月21日PCT公布。 出版物WO94 / 23648 日期：1994年10月27日一种旨在在核磁共振装置附近或内部实施的传感器装置，更具体地说是在磁共振成像器（MRI）的磁体的管内的患者身上。 该装置包括旨在施加到患者皮肤的至少两个非金属电极，以及用于由电极从心脏接收的电信号的电光转换，放大和滤波模块。 模块布置在形成法拉第笼的屏蔽套管中，并与显示器和/或监视装置光学连接。 由非磁性材料制成的支撑体承载包含模块的电极和屏蔽壳体。
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10.发明授权Monitor for surveying the vital physiological parameters of a patient undergoing NMR imaging 失效监测用于测量经历NMR成像的患者的重要生理参数
公开(公告)号：US5394873A
公开(公告)日：1995-03-07
申请号：US181863
申请日：1994-01-13
申请人： Michel Kraemer , Gerard Muller , Michel Lanoux
发明人： Michel Kraemer , Gerard Muller , Michel Lanoux
IPC分类号： A61B5/00 , A61B5/055 , G01R33/28 , G01R33/567 , A61B5/024
CPC分类号： A61B5/0555 , G01R33/28 , G01R33/5673
摘要： A general surveillance monitor to monitor the vital physiological signs of patients undergoing examination by nuclear magnetic resonance imaging is constructed such that each functional module of the monitor is individually protected from the electromagnetic environment and high frequency parasitic currents and such that the control assembly is a computer system without any magnetic storage.
摘要翻译： 构建了通过核磁共振成像来监测正在进行检查的患者的重要生理体征的一般监视监视器，使得监视器的每个功能模块被单独地保护免受电磁环境和高频率寄生电流的影响，并且使得控制组件是计算机 系统没有任何磁存储。
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