公开(公告)号：US20150374729A1

公开(公告)日：2015-12-31

申请号：US14315005

申请日：2014-06-25

Applicant: THE CLOROX COMPANY

Inventor： John Glauber ,  Matthew Harrington ,  Casper W. Chiang

IPC: A61K31/7004 ,  A61K31/045 ,  A01N25/08 ,  A61B19/02 ,  A01N37/02 ,  A01N31/02 ,  A61J1/05 ,  A61K31/191 ,  A01N47/44

CPC classification number: A61K31/7004 ,  A01N31/02 ,  A01N47/44 ,  A01N59/12 ,  A61B50/30 ,  A61B50/33 ,  A61B50/39 ,  A61B2050/0056 ,  A61B2050/0065 ,  A61B2050/3008 ,  A61K31/045 ,  A61K31/191 ,  A01N25/34

Abstract: The invention relates to methods and kits for use in reducing microbial counts on a patient's skin prior to surgery. Such a kit may be sealed, and include a dry substrate, a container of antiseptic composition, a tray with recessed portion(s), and a cover in sealing contact with a top rim of the tray to seal the contents in the tray. Such a kit may include two (e.g., identical) trays, which are initially attached to one another, each tray providing contents sufficient for one use (e.g., one use within 2 hours of the scheduled surgery, and a prior use done earlier (e.g., the night before). The related method may include providing the kit, removing the cover, dosing the substrate with the antiseptic composition in the tray's recessed region, and using the dosed substrate to apply the composition to skin proximate a location of the invasive procedure to be performed.

Abstract translation: 本发明涉及用于在手术之前减少患者皮肤上的微生物计数的方法和试剂盒。 这样的试剂盒可以是密封的，并且包括干燥的基材，防腐剂组合物的容器，具有凹陷部分的托盘，以及与托盘的顶部边缘密封接触以密封托盘中的内容物的盖子。 这样的工具包可以包括两个（例如，相同的）托盘，其最初彼此附接，每个托盘提供足以用于一次使用的内容物（例如，在预定的手术的2小时内使用一次使用，以及先前使用的先前使用（例如， 相关方法可以包括提供试剂盒，去除盖子，在托盘的凹陷区域中用防腐剂组合物给基质计量，并且使用给药的基质将组合物施用于接近侵入性程序的位置的皮肤 被执行。

公开(公告)号：US20140371695A1

公开(公告)日：2014-12-18

申请号：US14286509

申请日：2014-05-23

Applicant: THE CLOROX COMPANY

Inventor： Casper W. Chiang ,  BENJAMIN MA ,  BRADLEY L. KIRSCH

IPC: A61M35/00

CPC classification number: A61M35/006 ,  B29C49/04 ,  B29K2101/12 ,  B29K2509/00 ,  B29K2995/0029 ,  B29L2031/712 ,  B29L2031/7158 ,  B29L2031/7546

Abstract: The invention relates to applicators for applying a solution or other composition (e.g., an antiseptic composition) to skin of a patient. The applicator may include a container body having a proximal end, a distal end, and a frangible member disposed at the distal end of the body. The applicator includes a first position where the container body and frangible member are a unitary piece (e.g., blow molded as a single piece), and a second position when the frangible member is rotated relative to the body to irreversibly break a weak point therebetween, releasing the composition in the hollow body through an opening. A porous applicator head may be positioned adjacent the distal end of the body and frangible member, so that the composition flows out the body, through the opening, and onto the head. The applicator may be formed in a blow-fill-seal process for improved sterility and ease of manufacture.